Chemosensors,
Journal Year:
2023,
Volume and Issue:
11(4), P. 222 - 222
Published: April 4, 2023
The
emergence
of
the
SARS-CoV-2
virus
and
associated
pandemic
has
affected
entire
human
population.
Human
susceptibility
to
highlighted
a
tremendous
need
for
affordable
diagnostic
systems
manage
monitor
effectiveness
vaccination.
We
have
developed
simple
label-free
electrochemical
immunosensor
detection
anti-SARS-CoV-2
IgG
antibodies,
which
consists
supporting
screen-printed
carbon
electrode
(SPCE)
modified
with
an
electrodeposited
polyaniline
film
glutaraldehyde,
allowing
effective
immobilization
spike
glycoprotein
receptor-binding
domain
(RBD)
as
biorecognition
element.
impedimetric
showed
linear
response
over
wide
concentration
range
0.01–10
μg
mL−1,
that
is,
67
pM–6.7
nM,
low
limit
25.9
pM.
A
dual
working
configuration
built-in
negative
control
unit
was
demonstrated
practical
field
applications.
successfully
used
in
real
serum
sample
from
infected
patient
good
reproducibility
fair
agreement
ELISA.
An
optional
amplification
step
secondary
goat
anti-human
antibodies
demonstrated,
resulting
extended
0.93
Expert Opinion on Drug Delivery,
Journal Year:
2024,
Volume and Issue:
21(3), P. 457 - 477
Published: March 3, 2024
Introduction
Immediate
control
of
bleeding
and
anti-infection
play
important
roles
in
wound
management.
Multiple
organ
dysfunction
syndrome
death
may
occur
if
persistent
bleeding,
hemodynamic
instability,
hypoxemia
are
not
addressed.
The
combination
clay
hydrogel
provides
a
new
outlet
for
hemostasis.
In
this
review,
the
current
research
progress
hydrogel/clay
composite
hemostatic
agents
was
reviewed.
Advances in Natural Sciences Nanoscience and Nanotechnology,
Journal Year:
2023,
Volume and Issue:
14(3), P. 033001 - 033001
Published: Aug. 17, 2023
Abstract
A
critical
step
in
the
process
for
preventing
and
identifying
emergencies
relating
to
health,
safety,
welfare
is
testing
quick
diagnosis
of
microbial
pathogens.
Due
fast
spread
waterborne
food
borne
infections
society
high
costs
associated
with
them,
pathogen
identification
has
emerged
as
one
most
difficult
parts
water
sectors.
Since
turn
century,
pathogens
have
demonstrated
enormous
epidemiological
pandemic
potential.
The
emergence
dissemination
a
novel
virus
potential
endanger
livelihoods
well-being
individuals
worldwide.
severe
acute
respiratory
syndrome-coronavirus-2
(SARS-COV-2)
coronavirus
propagated
almost
every
country
on
Earth
had
considerable
negative
influence
economies
communities.
Despite
improvements
techniques
viral
diseases,
all
nations
must
now
execute
biosensing
speedy,
sensitive,
focused,
consistent
manner
order
address
pressing
global
issues.
Hence,
this
review,
we
critically
summarised
recent
advancement
electrochemical
well
optical
biosensors
monitoring
SARS-COV-2
various
Then,
began
by
providing
technical
overview
cutting-edge
strategies
utilised
combat
diseases
it,
including
utilisation
point-of-care
technology
(POCT),
artificial
intelligence
(AI),
internet
medical
things
(IoMT).
This
review
article
explores
integration
POC,
IoMT,
AI
technologies
context
personal
healthcare,
focusing
their
expedite
treatment
conditions,
ultimately
leading
improved
patient
outcomes.
Subsequently,
notion
execution
multiplex
are
presented
enhance
comprehension
detecting
multiple
analytes.
Finally,
conclusions
future
directions
been
presented.
Analytica Chimica Acta,
Journal Year:
2023,
Volume and Issue:
1278, P. 341614 - 341614
Published: July 11, 2023
Pathogens
cause
various
infectious
diseases
and
high
morbidity
mortality
which
is
a
global
public
health
threat.
The
highly
sensitive
specific
detection
of
significant
importance
for
the
effective
treatment
intervention
to
minimise
impact.
However,
conventional
methods
including
culture
molecular
method
gravely
depend
on
expensive
equipment
well-trained
skilled
personnel,
limiting
in
laboratory.
It
remains
challenging
adapt
resource-limiting
areas,
e.g.,
low
middle-income
countries
(LMICs).
To
this
end,
low-cost,
rapid,
tools
with
capability
field
testing
portable
device
identification
quantification
pathogens,
has
attracted
increasing
attentions.
Recently,
paper-based
microfluidic
analytical
devices
(μPADs)
have
shown
promising
tool
rapid
on-site
diagnosis,
providing
cost-effective
approach
pathogens
detection.
fast
turn-round
data
collection
may
also
contribute
better
understanding
risks
insights
mitigation
method.
In
paper,
critical
developments
μPADs
in-field
both
clinical
diagnostics
environmental
surveillance
are
reviewed.
future
development,
challenges
onsite
discussed,
using
cross-disciplinary
development
with,
emerging
techniques
such
as
deep
learning
Internet
Things
(IoT).
Biosensors,
Journal Year:
2023,
Volume and Issue:
13(7), P. 689 - 689
Published: June 28, 2023
The
utilization
of
electrochemical
detection
techniques
in
paper-based
analytical
devices
(PADs)
has
revolutionized
point-of-care
(POC)
testing,
enabling
the
precise
and
discerning
measurement
a
diverse
array
(bio)chemical
analytes.
application
sensing
paper
as
suitable
substrate
for
testing
platforms
led
to
emergence
(ePADs).
inherent
advantages
these
modified
have
gained
significant
recognition
POC
field.
In
response,
biosensors
assembled
from
materials
shown
great
promise
enhancing
sensitivity
improving
their
range
use.
addition,
numerous
advantageous
characteristics,
including
self-sufficient
conveyance
liquids,
reduced
resistance,
minimal
fabrication
cost,
environmental
friendliness.
This
study
seeks
provide
concise
summary
present
state
uses
ePADs
with
insightful
commentary
on
practicality
Future
developments
include
developing
novel
systems,
system
performance
biocatalyst,
combining
biosensor
other
cutting-edge
tools
such
machine
learning
3D
printing.
Inorganics,
Journal Year:
2023,
Volume and Issue:
11(5), P. 197 - 197
Published: May 1, 2023
COVID-19,
a
viral
respiratory
illness,
is
caused
by
Severe
Acute
Respiratory
Syndrome
Corona
Virus
2
(SARS-CoV-2),
which
was
first
identified
in
Wuhan,
China,
2019
and
rapidly
spread
worldwide.
Testing
isolation
were
essential
to
control
the
virus’s
transmission
due
severity
of
disease.
In
this
context,
there
global
interest
feasibility
employing
nano-biosensors,
especially
those
using
graphene
as
key
material,
for
real-time
detection
virus.
The
exceptional
properties
outstanding
performance
nano-biosensors
identifying
various
viruses
prompted
check
on
technology.
This
paper
focuses
recent
advances
graphene-based
electrochemical
biosensors
sensing
SARS-CoV-2
Specifically,
it
reviews
types
biosensors,
including
amperometric,
potentiometric,
impedimetric
discusses
current
challenges
associated
with
detection.
conclusion
review
future
directions
field
detection,
underscoring
importance
continued
research
development
domain.
