Enhanced Peroxidase-Mimic Catalytic Activity via Cerium Doping of Strontium-Based Metal–Organic Frameworks with Design of a Smartphone-Based Sensor for On-Site Salivary Total Antioxidant Capacity Detection in Lung Cancer Patients

ACS Applied Materials & Interfaces, Journal Year: 2023, Volume and Issue: 15(17), P. 21239 - 21251

Published: April 18, 2023

The development of artificial nanozymes with superior catalytic performance and excellent stability has been a long-standing objective for chemists. total antioxidant capacity (TAC) is one the most important bioanalytical measures oxidative stress in body. present work aims to develop smartphone-assisted visual detection sensor using cerium-doped strontium-based metal-organic frameworks (Ce-SrMOFs) as peroxidase-like rapid, low-cost, on-site TAC. pristine SrMOF functioned peroxidase nanozyme, its enzymatic activity was enhanced after doping it Ce(IV) ions because multivalent nature synergistic impact heteroatoms. Ce-SrMOFs were sensitive single electron transfer hydrogen atom processes, which implies that can serve an ideal nanozyme candidate TAC analysis. investigated mechanism revealed •OH active oxygen species activity. exhibited strong affinity 3,3',5,5'-tetramethylbenzidine (TMB) H2O2, Km values 0.082 0.427 mM, are 5.29- 8.67-fold lower than those horseradish (HRP), respectively. used ascorbic acid, cysteine, glutathione, limits 44, 53, 512 nM, proposed method proved effective measuring saliva samples from lung cancer patients, thereby yielding results satisfactory precision accuracy.

Language: Английский

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Intrinsic Dual-State Emission Zinc-Based MOF Rodlike Nanostructures with Applications in Smartphone Readout Visual-Based Detection for Tetracycline: MOF-Based Color Tonality

ACS Applied Materials & Interfaces, Journal Year: 2023, Volume and Issue: 15(39), P. 46098 - 46107

Published: Sept. 21, 2023

Dual-state emitters (DSEs) are entities that exhibit fluorescence in both the solution and solid state, which open up a wide range of possibilities for their utilization various fields. The development detection platforms using intrinsic luminescent metal-organic frameworks (LMOFs) is highly desirable variety applications. DSE MOFs as subclass LMOFs attractive due to no need encapsulation/functionalization by fluorophores and/or linkers. Herein, stable dual-state blue emission (λem = 425 nm) zinc-based MOF with rodlike nanostructures (denoted UoZ-2) was synthesized characterized. To best our knowledge, Zn-MOFs dispersed form solid-state have not been reported yet. When tetracycline (TC) added, continuous color evolution from greenish-yellow dramatic enhancement observed aggregation induced (AIE). Thus, sensitive ratiometry-based visual platform, on paper independently, designed TC exploiting AIE properties UoZ-2 alone UoZ-2:TC. limit estimated be 4.5 nM, considered one most ratiometric fluorescent probes sensing. ratiometry paper-based sensor displays reliable quantitative analysis recognizing RGB values on-site satisfactory recoveries.

Language: Английский

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Temperature-resilient and sustainable Mn-MOF oxidase-like nanozyme (UoZ-4) for total antioxidant capacity sensing in some citrus fruits: Breaking the temperature barrier

Food Chemistry, Journal Year: 2024, Volume and Issue: 448, P. 139170 - 139170

Published: March 29, 2024

Language: Английский

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Recent Advances of Bimetallic-Metal Organic Frameworks: Preparation, Properties, and Fluorescence-Based Biochemical Sensing Applications

ACS Applied Materials & Interfaces, Journal Year: 2024, Volume and Issue: 16(25), P. 31895 - 31921

Published: June 13, 2024

Bimetallic-metal organic frameworks (BiM-MOFs) or bimetallic represent an innovative and promising class of porous materials, distinguished from traditional monometallic MOFs by their incorporation two metal ions alongside linkers. BiM-MOFs, with unique crystal structure, physicochemical properties, composition, demonstrate distinct advantages in the realm biochemical sensing applications, displaying improvements optical stability, selectivity, sensitivity. This comprehensive review explores into recent advancements leveraging BiM-MOFs for fluorescence-based sensing, providing insights design, synthesis, practical applications both chemical biological sensing. Emphasizing fluorescence emission as a transduction mechanism, aims to guide researchers maximizing potential across broader spectrum investigations. Furthermore, it prospective research directions addresses challenges, offering valuable perspectives on evolving landscape probes rooted BiM-MOFs.

Language: Английский

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Merging Dual Antenna Effect with Target-Insensitive Behavior in Bimetal Biligand MOFs to Form Efficient Internal Reference Signal: Color Tonality-Ratiometric Designs

ACS Materials Letters, Journal Year: 2024, Volume and Issue: 6(6), P. 2339 - 2349

Published: May 14, 2024

The construction of a highly luminescent, stable, and target-insensitive internal reference signal is significant in ratiometric color tonality applications. Improvement the antenna effect, efficient mechanism that enhances luminescence emission via sensitization, an effective route to obtain bright luminescence. Additionally, manipulation crystal structure morphology key issue control reactivity, especially metal–organic frameworks (MOFs). In present work, novel red emitter Eu/Zn bimetal biligand MOF (UoZ-5) was synthesized used as signal. A dual-antenna from triplet states (T1) ligands 5Do Eu3+ ion, observed explained on basis energy levels. With UoZ-5 serving reference, blue-emitting carbon quantum dots (CQDs) selective for Ag+ ions nonfluorescent composite, CQDs@Ag+, probe vitamin B1, tonality-based platform analysis were developed.

Language: Английский

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A novel ratiometric design of microfluidic paper-based analytical device for the simultaneous detection of Cu²⁺ and Fe³⁺ in drinking water using a fluorescent MOF@tetracycline nanocomposite

Lab on a Chip, Journal Year: 2024, Volume and Issue: 24(8), P. 2306 - 2316

Published: Jan. 1, 2024

On-site monitoring of ions in drinking water is essential for safeguarding public health, ensuring high quality, and preserving the ecological balance aquatic ecosystems.

Language: Английский

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Sensitive dual-signal detection and effective removal of tetracycline antibiotics in honey based on a hollow triple-metal organic framework nanozymes

Food Chemistry, Journal Year: 2024, Volume and Issue: 442, P. 138383 - 138383

Published: Jan. 10, 2024

Language: Английский

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Three in one: coordination-induced emission for inherent fluorescent Al-MOF synthesis combined with inner filter effect@aggregation-induced emission mechanisms for designing color tonality and ratiometric sensing platforms

Microchimica Acta, Journal Year: 2024, Volume and Issue: 191(8)

Published: July 11, 2024

Language: Английский

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Molecular imprinting-based triple-emission ratiometric fluorescence sensor with aggregation-induced emission effect for visual detection of doxycycline

Journal of Hazardous Materials, Journal Year: 2024, Volume and Issue: 470, P. 134218 - 134218

Published: April 4, 2024

Language: Английский

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Multifunctional MOF: Cold/hot adapted sustainable oxidase-like MOF nanozyme with ratiometric and color tonality for nitrite ions detection

Food Chemistry, Journal Year: 2024, Volume and Issue: 462, P. 141027 - 141027

Published: Aug. 28, 2024

Language: Английский

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