Tracing nitroxyl in vivo with a high fluorescence quantum yield and large Stokes shift near-infrared fluorescent probe

Sensors and Actuators B Chemical, Journal Year: 2024, Volume and Issue: 418, P. 136310 - 136310

Published: July 16, 2024

Language: Английский

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Optimization of Ultrasonic-Assisted Extraction of Phenolic Compounds and Antioxidant Activity from Araticum Peel Using Response Surface Methodology

Plants, Journal Year: 2024, Volume and Issue: 13(18), P. 2560 - 2560

Published: Sept. 12, 2024

The peel represents a significant portion of the araticum fruit (about 40%), which becomes waste after its consumption or processing. Previous studies have shown that is rich in phenolic compounds; however, little known about ideal conditions for recovering these compounds. Therefore, response surface methodology, using central composite rotatable design, was employed to optimize extraction process maximize total compounds (TPCs) and enhance Trolox equivalent antioxidant capacity (TEAC) from peel. variables optimized were ethanol concentration (EC; 20-80%,

Language: Английский

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Root Exudates Mediate the Production of Reactive Oxygen Species in Rhizosphere Soil: Formation Mechanisms and Ecological Effects

Plants, Journal Year: 2025, Volume and Issue: 14(9), P. 1395 - 1395

Published: May 6, 2025

Reactive oxygen species (ROS), as redox messengers, play an important role in regulating plant growth, sensing biotic and abiotic stresses, integrating different environmental signals. As the microenvironment of interaction between root, soil microorganism, rhizosphere is hotspot ROS production action. Root exudates are medium for communication roots environment, they have a significant regulatory effect on rhizosphere. At same time, formation determined by coupling various factors, it also affected stresses such temperature, humidity, disease. This review summarizes how root affect growth induce defense mechanisms generation distribution ROS. It discusses promoting decomposition organic matter, nutrient cycling, pollutant degradation transformation. In-depth study regulation mechanism not only helps to reveal molecular adaptation stress but provides theoretical support practical guidance sustainable agricultural development ecological environment protection.

Language: Английский

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Possible Molecular Mechanisms of Hypertension Induced by Sleep Apnea Syndrome/Intermittent Hypoxia

Life, Journal Year: 2024, Volume and Issue: 14(1), P. 157 - 157

Published: Jan. 22, 2024

Intermittent hypoxia (IH) is a central characteristic of sleep apnea syndrome (SAS), and it subjects cells in the body to repetitive apnea, chronic hypoxia, oxygen desaturation, hypercapnia. Since SAS linked various serious cardiovascular complications, especially hypertension, many studies have been conducted elucidate mechanism hypertension induced by SAS/IH. Hypertension associated with numerous disorders. As most common complication SAS, cell animal models study SAS/IH developed provided lots hints for elucidating molecular mechanisms IH. However, detailed are obscure under investigation. This review outlines IH, which include regulation systems reactive species (ROS) that activate renin-angiotensin system (RAS) catecholamine biosynthesis sympathetic nervous system, resulting hypertension. And hypoxia-inducible factors (HIFs), Endotheline 1 (ET-1), inflammatory also mentioned. In addition, we will discuss influences dysfunction relationship microRNA (miRNA)s regulate key molecules each mechanism, has become more apparent recent years. These findings provide insight into pathogenesis help development future treatments.

Language: Английский

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A fluorescence probe with targeted mitochondria was developed for detecting H2O2 in vitro and vivo

Microchemical Journal, Journal Year: 2024, Volume and Issue: 201, P. 110656 - 110656

Published: April 30, 2024

Language: Английский

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Recent progress in small-molecule fluorescent probes for the detection of superoxide anion, nitric oxide, and peroxynitrite anion in biological systems

Chemical Science, Journal Year: 2024, Volume and Issue: unknown

Published: Jan. 1, 2024

In this review, we summarized the latest progress (2020–2023) in small-molecule fluorescent probes for monitoring superoxide anion (O 2 ˙ − ), nitric oxide (NO), and peroxynitrite (ONOO ) biological systems.

Language: Английский

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Oxidative cyclization of N-(2-oxo-4-phenyl-1,2-dihydropyridin-3-yl)thioureas to 7-phenyloxazolo[5,4-b]pyridin-2-amines

Russian Chemical Bulletin, Journal Year: 2024, Volume and Issue: 73(7), P. 2004 - 2013

Published: July 1, 2024

Language: Английский

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Fluorescence lifetime imaging of human pancreatic lipase activity using a novel probe for early diagnosis of severe acute pancreatitis

Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy, Journal Year: 2024, Volume and Issue: 326, P. 125171 - 125171

Published: Sept. 21, 2024

Language: Английский

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A protein structure-dependent fluorescent probe for hemoglobin monitoring and controllable imaging in living cells

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 283, P. 137868 - 137868

Published: Nov. 19, 2024

Language: Английский

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Peroxynitrite as biomarker to evaluate the rehabilitation of cisplatin in the resistant cells with miR-125a-5p by using fluorescent assay

Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy, Journal Year: 2024, Volume and Issue: 330, P. 125663 - 125663

Published: Dec. 27, 2024

Reactive oxygen species (ROS) play a dual role in the chemotherapy of cancer with cisplatin, providing both anti-tumor effects and contributing to drug resistance at various stages treatment which seriously affects effectiveness. The detailed mechanism ROS is urgently necessary be explored. To address this issue non-small-cell lung (NSCLC) cisplatin-resistance, reliable assay was developed by synthesizing characterizing an interesting near-infrared (NIR) ONOO

Language: Английский

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