A novel ratiometric BenzoBODIPY-Based fluorescent probe for the detection and imaging of Cysteine in living cells and zebrafish models DOI

Jiangming Fan,

Bin Lin,

Shuqi Tang

et al.

Talanta, Journal Year: 2024, Volume and Issue: 285, P. 127332 - 127332

Published: Dec. 5, 2024

Language: Английский

A novel LD-targeting cysteine-activated fluorescent probe for diagnosis of APAP-induced liver injury and its application in food analysis DOI
Zhiqiang Yang, Xin Kang, Jia Li

et al.

Food Chemistry, Journal Year: 2024, Volume and Issue: 456, P. 140064 - 140064

Published: June 12, 2024

Language: Английский

Citations

10
A novel π-bridge rationally designed polarity-viscosity-sensitive probe for lipid imaging DOI

Mingzhen Chao,

Haitao Zhang,

Qingfei Hu

et al.

Dyes and Pigments, Journal Year: 2024, Volume and Issue: 225, P. 112088 - 112088

Published: March 15, 2024

Language: Английский

Citations

3
Construction of a mitochondrial targeted H2O2 fluorescence probe with a large Stokes shift and its application in bacterial infection DOI

Jindong Ai,

Yibo Cui,

Mingguang Ren

et al.

Dyes and Pigments, Journal Year: 2024, Volume and Issue: 225, P. 112103 - 112103

Published: March 22, 2024

Language: Английский

Citations

3
Visual monitoring of hydrazine in food and environmental samples by wearable probe DOI
Beibei Wang, Maurizio Quinto, Wenxiang He

et al.

Journal of Hazardous Materials, Journal Year: 2024, Volume and Issue: 480, P. 136384 - 136384

Published: Nov. 2, 2024

Language: Английский

Citations

2
Fabrication of a Near-Infrared-Emissive Probe for Detecting Dipeptidyl Peptidase 4 in the Liver of Diabetic Mice and Clinical Serum DOI

Minhui Liu,

Jiayu Zeng, Wanting Zhang

et al.

Analytical Chemistry, Journal Year: 2024, Volume and Issue: 96(29), P. 11890 - 11896

Published: July 10, 2024

Dipeptidyl peptidase 4 (DPP4) plays a key role in glucose metabolism, which has been close target for diabetes pathology and treatment. It is significant the evaluation of cellular DPP4 activity various biological systems. Fluorescence imaging technology currently popular method detecting enzymes living cells due to its advantages high selectivity, sensitivity, spatiotemporal resolution, real-time visualization. Herein, near-infrared (NIR)-emissive probe

Language: Английский

Citations

1
Zero background fluorescent probe for sensing and imaging of glutathione via the “covalent-assembly” approach DOI
Zheng Yang, Zhiyao Wang, Y. Y. Peng

et al.

Organic & Biomolecular Chemistry, Journal Year: 2024, Volume and Issue: 22(39), P. 8024 - 8031

Published: Jan. 1, 2024

Developing selective and sensitive fluorescent probes for the detection of glutathione (GSH) concentration intracellular distribution is great significance early diagnosis treatment diseases such as liver injury cancer since GSH plays irreplaceable roles in regulating redox homeostasis. Herein, we present a new probe that can be specifically activated by through conjugate addition hydrolysis induced covalent-assembly approach achieving zero-background interference fluorescence off-on sensing. Besides, exhibited prominent selectivity sensitivity, low limit cytotoxicity, thus successfully realizing specific real-time monitoring tracking levels living cells. As consequence, this work might provide potentially promising candidate validating function various physiological pathological processes, which beneficial therapeutics related diseases.

Language: Английский

Citations

1
A novel Golgi-targetable isocyano-based cysteine-specific fluorescent probe for the visualization of cysteine during drug-induced oxidative stress DOI
Caiyun Liu,

Xiaodi Rong,

Xin Zhao

et al.

Sensors and Actuators B Chemical, Journal Year: 2024, Volume and Issue: 422, P. 136565 - 136565

Published: Sept. 4, 2024

Language: Английский

Citations

1
TDDFT elucidating the PET-Inhibition Mediated fluorescence enhancement in a Cysteine probe DOI

You-Qian Ma,

Hang Zhang, Yan Zhang

et al.

Chemical Physics Letters, Journal Year: 2024, Volume and Issue: 856, P. 141683 - 141683

Published: Oct. 11, 2024

Language: Английский

Citations

1
Novel ruthenium(II) complex-based two-photon luminescent probe for visualizing biothiols in ferroptosis-mediated hepatic ischemia-reperfusion injury DOI
Lin Jiang, Chaolong Liu, Jie Wang

et al.

Talanta, Journal Year: 2024, Volume and Issue: 283, P. 127176 - 127176

Published: Nov. 7, 2024

Language: Английский

Citations

1
A Highly Effective Curcumin-Based Fluorescent Probe with Single-Wavelength Excitation for Simultaneous Detection and Bioimaging of Cys, Hcy and Gsh DOI
Wenhao Du, Xin Zhou, Chunjie Zhang

et al.

Published: Jan. 1, 2024

Cysteine (Cys), homocysteine (Hcy) and glutathione (GSH) act as significant roles in many physiological processes, their abnormal proliferation will cause multiple diseases including Alzheimer's disease, Parkinson's Cardiovascular atherosclerosis, soft tissue damage. However, It is challenging work to develop a efficient method for differentiating detecting GSH, Cys Hcy because of similarity structures functions. In this work, smart fluorescent probe FBCN based on curcumin was rationally devised developed by etherifying the phenol hydroxyl group FBC with NBD-Cl, which emitted strong green at 516 nm. distinguished from Cys/GSH naked eyes color variation solution sunlight. Meanwhile, GSH induced powerful fluorescence quenching solution, but transformed luminous yellow accompanied emission wavelength redshifted nm 540 or 553 existence Cys, respectively. Probe had outstanding sensitivity anti-interference, low detection limit (61.6 nM, 77.7 0.29 µM corresponded Hcy, respectively), short response time (the 1 min, 2 min 5 respectively). The DFT calculation HRMS verified sensing mechanism biothiols. addition, successfully utilized detect three biothiols levels living cell zebrafish.

Language: Английский

Citations

0