Pt-S Bond Stabilized Dnazyme Nanosensor With Thiol-Resistance Enabling High-Fidelity Biosensing DOI
Yanli Lei,

Xinyan He,

Yu Zeng

et al.

Published: Jan. 1, 2024

Download This Paper Open PDF in Browser Add to My Library Share: Permalink Using these links will ensure access this page indefinitely Copy URL DOI

Language: Английский

Exploration and Application of the Catalytic Superiority of Non-G-Quadruplex Hemin Aptamers DOI
Changjiang Li, Xiaolong Li, Shichao Wei

et al.

Analytical Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 5, 2025

A newly identified hemin aptamer with a non-G-quadruplex structure exhibits stronger peroxidase activity and selectivity than traditional G-quadruplex/hemin DNAzymes, addressing challenges such as weak binding, low catalytic activity, poor selectivity. In this study, we optimized ion activation conditions, refined reaction parameters, developed spontaneous recombination method via splitting to enhance DNAzyme enable regulation. The demonstrated superior performance in enzyme-free sensing, polymerase-assisted amplification, CRISPR/Cas12a systems, achieving higher sensitivity improved colorimetric thresholds compared G-quadruplexes. We have also comprehensive operational guide for aptamer/hemin which is poised revolutionize sensor signal generation elements.

Language: Английский

Citations

0
Highly-sensitive and logic platform based on spatially-constrained T7 transcription enhanced Cas13a for DNA repair enzyme detection and intracellular imaging DOI
Dongsheng Shen, Hongxia Guo, Fubin Zhang

et al.

Biosensors and Bioelectronics, Journal Year: 2025, Volume and Issue: unknown, P. 117406 - 117406

Published: March 1, 2025

Language: Английский

Citations

0
G-quadruplex/hemin DNAzyme mediated biosensor for colorimetric detection of trace aflatoxin B1 using entropy-driven catalytic reaction-facilitated catalytic hairpin assembly DOI
Dian Yu, Yingying Sun, Xin Lin

et al.

Journal of Food Composition and Analysis, Journal Year: 2025, Volume and Issue: unknown, P. 107622 - 107622

Published: April 1, 2025

Language: Английский

Citations

0
Structure-switchable dsDNA promoter regulates the activity of CRISPR-Cas12a for APE1 detection DOI

Xingrong Li,

Yumei Li,

Cuixiang Wang

et al.

Talanta, Journal Year: 2025, Volume and Issue: 294, P. 128161 - 128161

Published: April 15, 2025

Language: Английский

Citations

0
Pt–S bond stabilized DNAzyme nanosensor with thiol-resistance enabling high-fidelity biosensing DOI
Yanli Lei,

Xinyan He,

Yu Zeng

et al.

Talanta, Journal Year: 2024, Volume and Issue: 276, P. 126187 - 126187

Published: April 29, 2024

Language: Английский

Citations

3
A target-triggered colorimetric sensor for ultrasensitive detection of miRNAs based on self-powered three-dimensional DNA walker DOI
Yingxue Li, Tingrui Zhang, Gang Bai

et al.

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 279, P. 135370 - 135370

Published: Sept. 13, 2024

Language: Английский

Citations

1
Pt-S Bond Stabilized Dnazyme Nanosensor With Thiol-Resistance Enabling High-Fidelity Biosensing DOI
Yanli Lei,

Xinyan He,

Yu Zeng

et al.

Published: Jan. 1, 2024

Download This Paper Open PDF in Browser Add to My Library Share: Permalink Using these links will ensure access this page indefinitely Copy URL DOI

Language: Английский

Citations

0