A Fluorescent Probe with Large Stokes Shift Based on Benzothiadiazole Scaffolds for Selective Detection of Hg2+ in Lysosomes and Its Application in Biological Imaging DOI Open Access

Lin Wang,

Ning Zhang,

Yuan He

et al.

Chemistry - An Asian Journal, Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 31, 2024

Abstract Mercury is highly toxic, and appropriate amounts of the mercury‐selenium complex can protect plasma. However, when excessive mercury (II) ions (Hg 2+ ) are exposed to human skin or ingested directly, it lead irreversible accumulation in body. Therefore, detecting presence Hg cells important. A novel fluorescent probe BTD‐Hg‐Lyso was designed constructed based on intramolecular charge transfer mechanism. Thiotaldehyde could specifically recognize so that produce a fluorescence enhancement effect. In addition, exhibited advantages large Stokes shift (210 nm) good selectivity. More importantly, be used for determination cellular lysosomes. able image HeLa cells, zebrafish, tobacco seedlings (rhizome stem) successfully.

Language: Английский

Near-infrared probes based on naphthyridine malononitrile units for monitoring the viscosity fluctuation of lysosomes and endoplasmic reticulum during autophagy and ferroptosis DOI
Hui Wang, Jingyu Zhao, Ru Sun

et al.

Microchemical Journal, Journal Year: 2025, Volume and Issue: unknown, P. 113344 - 113344

Published: March 1, 2025

Language: Английский

Citations

0
A Fluorescent Probe with Large Stokes Shift Based on Benzothiadiazole Scaffolds for Selective Detection of Hg2+ in Lysosomes and Its Application in Biological Imaging DOI Open Access

Lin Wang,

Ning Zhang,

Yuan He

et al.

Chemistry - An Asian Journal, Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 31, 2024

Abstract Mercury is highly toxic, and appropriate amounts of the mercury‐selenium complex can protect plasma. However, when excessive mercury (II) ions (Hg 2+ ) are exposed to human skin or ingested directly, it lead irreversible accumulation in body. Therefore, detecting presence Hg cells important. A novel fluorescent probe BTD‐Hg‐Lyso was designed constructed based on intramolecular charge transfer mechanism. Thiotaldehyde could specifically recognize so that produce a fluorescence enhancement effect. In addition, exhibited advantages large Stokes shift (210 nm) good selectivity. More importantly, be used for determination cellular lysosomes. able image HeLa cells, zebrafish, tobacco seedlings (rhizome stem) successfully.

Language: Английский

Citations

0