Delaying liver aging: Analysis of structural and functional alterations DOI
Yuqin Yao,

Qiong-Yue Cao,

Zheng Li

et al.

World Journal of Gastroenterology, Journal Year: 2025, Volume and Issue: 31(15)

Published: April 17, 2025

This article is based on a recent bibliometric analysis of research progress liver aging. The notable for its extraordinary ability to rejuvenate, thereby safeguarding and maintaining the organism’s integrity. With advancing age, there noteworthy reduction in both liver’s size blood circulation. Furthermore, wide range physiological alterations driven by aging may foster development illnesses. Previous studies indicate that linked impaired lipid metabolism abnormal gene expression associated with chronic inflammation. Factors such as mitochondrial dysfunction telomere shortening accumulate, which result increased hepatic steatosis, impacts regeneration, metabolism, other functions. Knowing structural functional changes could help elderly adults delay Increasing public awareness anti-aging interventions essential. Besides use dietary supplements, lifestyle, including habits physical exercise routines, are most efficacious means decelerate process liver. highlights advances mechanism summarizes promising intervention options preventing related diseases.

Language: Английский

Nanosensors Based on Breathomics for Human Disease Diagnosis: a New Frontier in Personalized Healthcare DOI Creative Commons
Bakr Ahmed Taha, Ali J. Addie, Adawiya J. Haider

et al.

BioNanoScience, Journal Year: 2025, Volume and Issue: 15(2)

Published: March 14, 2025

Language: Английский

Citations

0
A Review on Optical Biosensors for Monitoring of Uric Acid and Blood Glucose Using Portable POCT Devices: Status, Challenges, and Future Horizons DOI Creative Commons
Kermue Vasco Jarnda, Heng Dai, Anwar Ali

et al.

Biosensors, Journal Year: 2025, Volume and Issue: 15(4), P. 222 - 222

Published: March 31, 2025

The growing demand for real-time, non-invasive, and cost-effective health monitoring has driven significant advancements in portable point-of-care testing (POCT) devices. Among these, optical biosensors have emerged as promising tools the detection of critical biomarkers such uric acid (UA) blood glucose. Different transduction methods, like fluorescence, surface plasmon resonance (SPR), colorimetric approaches, are talked about, with a focus on how sensitive, specific, they are. Despite considerable advancements, several challenges persist, including sensor stability, miniaturization, interference effects, need calibration-free operation. This review also explores issues related to cost-effectiveness, data integration, wireless connectivity remote monitoring. further examines regulatory considerations commercialization aspects biosensors, addressing gap between research developments clinical implementation. Future perspectives emphasize integration artificial intelligence (AI) healthcare improved diagnostics, alongside development wearable implantable continuous Innovative potential change way people manage their by quickly accurately measuring glucose levels. is especially true decentralized solutions grows. By critically evaluating existing work exploring limitations opportunities field, this will help guide more efficient, accessible, reliable POCT devices that can improve patient outcomes quality life.

Language: Английский

Citations

0
Artificial Intelligence Advancements in Oncology: A Review of Current Trends and Future Directions DOI Creative Commons

Ellen N. Huhulea,

Lillian Huang,

Shirley Eng

et al.

Biomedicines, Journal Year: 2025, Volume and Issue: 13(4), P. 951 - 951

Published: April 13, 2025

Cancer remains one of the leading causes mortality worldwide, driving need for innovative approaches in research and treatment. Artificial intelligence (AI) has emerged as a powerful tool oncology, with potential to revolutionize cancer diagnosis, treatment, management. This paper reviews recent advancements AI applications within research, focusing on early detection through computer-aided personalized treatment strategies, drug discovery. We survey AI-enhanced diagnostic explore techniques such deep learning, well integration nanomedicine immunotherapy care. Comparative analyses AI-based models versus traditional methods are presented, highlighting AI’s superior potential. Additionally, we discuss importance integrating social determinants health optimize Despite these advancements, challenges data quality, algorithmic biases, clinical validation remain, limiting widespread adoption. The review concludes discussion future directions emphasizing its reshape care by enhancing personalizing treatments targeted therapies, ultimately improving patient outcomes.

Language: Английский

Citations

0
Delaying liver aging: Analysis of structural and functional alterations DOI
Yuqin Yao,

Qiong-Yue Cao,

Zheng Li

et al.

World Journal of Gastroenterology, Journal Year: 2025, Volume and Issue: 31(15)

Published: April 17, 2025

This article is based on a recent bibliometric analysis of research progress liver aging. The notable for its extraordinary ability to rejuvenate, thereby safeguarding and maintaining the organism’s integrity. With advancing age, there noteworthy reduction in both liver’s size blood circulation. Furthermore, wide range physiological alterations driven by aging may foster development illnesses. Previous studies indicate that linked impaired lipid metabolism abnormal gene expression associated with chronic inflammation. Factors such as mitochondrial dysfunction telomere shortening accumulate, which result increased hepatic steatosis, impacts regeneration, metabolism, other functions. Knowing structural functional changes could help elderly adults delay Increasing public awareness anti-aging interventions essential. Besides use dietary supplements, lifestyle, including habits physical exercise routines, are most efficacious means decelerate process liver. highlights advances mechanism summarizes promising intervention options preventing related diseases.

Language: Английский

Citations

0