Triple-Standard Hypochlorite Quantitative Array Enabled by Precise Stokes Shift Modulation in D-π-A Chemodosimeters

Analytical Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: April 25, 2025

The rational design of the D-π-A chemodosimeter with a significant Stokes shift is great importance for enhancing visualization optical sensing signals. Here, three fluorescent chemodosimeters 2-(3-cyano-4,5,5-trimethylfuran-2(5H)-ylidene) malononitrile (TCF) as electron-withdrawing group are synthesized by precisely modulating electron-releasing strength. By decreasing ability electron release, electrophilicity recognition site increased 1.449 kcal/mol, improved to 201 nm, and mode changes from fluorescence quenching ratiometric finally on. Furthermore, display superior performance toward ClO-, including low limits detection (LOD, 37.0, 5.1, 1.0 nM), rapid response (<5 s), selectivity in presence 16 kinds interferents. Moreover, practicality further validated portable triple-standard quantitative array platform, which can quantitatively detect ClO- solutions. proposed modulation strategy provide new pathway sensitive visualized identification oxidants other hazardous chemicals.

Language: Английский

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AIE and ICT Synergistic Lysosome-Targeted Ratiometric Fluorescence Sensor for the Detection and Imaging of Th⁴⁺ in the Liver of Zebrafish and Mice

Analytical Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: March 10, 2025

The sensitive detection of the radioactive thorium (Th) ion with an oxidation state +4 (Th4+) is great significance for environmental protection and life safety. In this study, five fluorescence sensors regulated donor-acceptor (D-A) interactions were constructed Th4+ based on intramolecular charge transfer aggregation-induced emission mechanisms. Among developed sensors, TPE-D bearing electron-deficient π-bridge weak D-A presented ratiometric behavior toward in aqueous solution due to its characteristics unique D-A-D structures. Moreover, showed excellent selectivity sensitivity detection, limit was as low 8.1 × 10-8 M. sensing mechanism observation revealed that could coordinate hydroxyl, imine, carbonyl groups accompanied by electron process. addition, selectively be enriched lysosome. Both lysosome liver mice zebrafish realized strategy, a mobile-assisted approach actual water samples also established high sensitivity. This first report organelles organs, which provides reliable strategy radionuclide toxicology analysis applications.

Language: Английский

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Advances in Nanostructured Fluorescence Sensors for H2O2 Detection: Current Status and Future Direction

Micro, Journal Year: 2025, Volume and Issue: 5(2), P. 15 - 15

Published: March 21, 2025

Hydrogen peroxide (H2O2) detection in both liquid and gas phases has garnered significant attention due to its importance various biological industrial processes. Monitoring H2O2 levels is essential for understanding effects on biology, industry, the environment. Significant advancements physical dimensions performance of biosensors have been made, mainly through integration fluorescence techniques nanotechnology. These resulted more sensitive, selective, versatile systems, enhancing our ability monitor effectively. However, limited comprehensive reviews exist vaporized H2O2, which used disinfection production explosive agents, making vital. This review provides an overview recent progress nanostructured sensors detection, covering phases. It examines fluorescence-based methods focuses emerging nanomaterials sensor development. Additionally, it discusses dual applications biomedical non-biomedical fields, offering insights into current state field future directions. Finally, challenges perspectives developing novel are presented guide research this rapidly evolving area.

Language: Английский

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Machine Learning-Driven Surface Plasmon-Enhanced Dual Spectroscopies Improve Recognition and Real-Time Monitoring of Hazardous Chemicals

Analytical Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: April 11, 2025

To address the challenges of precise identification and real-time monitoring hazardous chemicals, this work proposes develops surface-plasmon-enhanced dual spectroscopies (SPEDS). This technique combines highly recognizable surface-enhanced Raman spectroscopy (SERS) with plasmon-mediated differential ultraviolet-visible (P-DUS). The feasibility is demonstrated by successfully acquiring SPEDS signals thiourea a plasmonic gold colloidal system. By combining machine learning algorithms, we achieve accurate quantification accuracies 98.2 98.6%, respectively, significantly outperforming single P-DUS (63.2 95.1%) SERS (80.3 86.5%). Additionally, demonstrate universality expandability through other nanostructures various shapes surface modifications. Using CuS-coated Au nanoarray, multiple 8-h sessions Hg2+ good anti-interference robust quantification, thereby highlighting practical potential in real-world applications. These results position as cutting-edge multifunctional chemical sensing platform, unlocking transformative possibilities for advancing environmental monitoring, industrial safety, public health.

Language: Английский

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Surface etching nano-flowers of Fe-Mn bimetallic oxide nano-cubes: determination of L-cysteine by its oxidase activity

Journal of Food Composition and Analysis, Journal Year: 2025, Volume and Issue: unknown, P. 107734 - 107734

Published: May 1, 2025

Language: Английский

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Intelligent Materials and Nanomaterials Improving Physical Properties and Control Oriented on Electronic Implementations

Electronics, Journal Year: 2023, Volume and Issue: 12(18), P. 3772 - 3772

Published: Sept. 6, 2023

The review highlights possible research topics matching the experimental physics of matter with advances in electronics to improve intelligent design and control innovative smart materials. Specifically, following European guidelines Key Enabling Technologies (KETs), I propose different suitable for project proposals research, including nanomaterials, nanocomposite materials, nanotechnology, artificial intelligence (AI), a focus on implementation. paper provides new framework addressing study AI driving electronic systems procedures determine physical properties versatile materials dynamically material’s “self-reaction” when applying external stimuli. proposed allows one ideate circuital solutions be integrated embedded formed algorithms circuits. challenge is bring together concepts regarding provide direction applications. discussed are classified as Technology Readiness Levels (TRL) 1 2.

Language: Английский

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Rational design of niobium carbide MXene quantum dots decorated with arginine for the fluorescence sensing of superoxide anion in Saccharomyces cerevisiae cells

Sensors and Actuators B Chemical, Journal Year: 2023, Volume and Issue: 404, P. 135226 - 135226

Published: Dec. 23, 2023

Language: Английский

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A Cascade Activation Probe with Double-Enhanced Near-Infrared Imaging for Monitoring Peroxynitrite Fluctuations in Vivo

Analytical Chemistry, Journal Year: 2024, Volume and Issue: 96(44), P. 17657 - 17664

Published: Oct. 23, 2024

Monitoring peroxynitrite (ONOO

Language: Английский

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Facile access to a methylthiocoumarinyl formate as highly selective and sensitive fluorescent probe for hypochlorite

Chemical Papers, Journal Year: 2024, Volume and Issue: 78(6), P. 3607 - 3615

Published: Feb. 15, 2024

Language: Английский

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A Ratiometric Fluorescence Probe Based on Silver Nanoclusters and CdSe/ZnS Quantum dots for the Detection of Hydrogen Peroxide by Aggregation and Etching

Journal of Fluorescence, Journal Year: 2024, Volume and Issue: unknown

Published: June 22, 2024

Language: Английский

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