Mechanism of Environmental Endocrine Disruptors in Polycystic Ovary Syndrome
嘉玲 刘
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Advances in Clinical Medicine,
Journal Year:
2025,
Volume and Issue:
15(02), P. 775 - 781
Published: Jan. 1, 2025
Language: Английский
Special Issue “New Challenges and Perspectives in Polycystic Ovary Syndrome”
International Journal of Molecular Sciences,
Journal Year:
2025,
Volume and Issue:
26(6), P. 2665 - 2665
Published: March 15, 2025
Polycystic
ovary
syndrome
(PCOS)
is
a
complex
multisystem
metabolic
and
endocrine
disorder
that
impacts
health
throughout
the
lifespan
[...]
Language: Английский
PCOS Programming and Transmission Across Generations
Annales d Endocrinologie,
Journal Year:
2025,
Volume and Issue:
86(3), P. 101774 - 101774
Published: May 6, 2025
Language: Английский
The Role of Gene Alterations in the Pathogenesis of Polycystic Ovary Syndrome
Journal of Clinical Medicine,
Journal Year:
2025,
Volume and Issue:
14(10), P. 3347 - 3347
Published: May 12, 2025
Family
studies
have
shown
that
polycystic
ovary
syndrome
(PCOS)
has
probable
genetic
transmission
because
of
a
high
incidence
relatives
who
present
clinical
or
biochemical
characters
the
syndrome.
However,
initial
candidate
gene
were
unsuccessful.
Genome
wide
association
(GWASs)
at
least
29
alterations
are
common
in
PCOS,
but
it
been
calculated
altered
genes
found
by
GWASs
may
represent
only
10%
affected
patients.
Rare
uncoding
explain
an
additional
group
In
many
other
patients,
risk
condition
for
development
syndrome,
and
new
some
mainly
concern
androgen
production
be
PCOS.
Finally,
most
epigenetic
environmental
factors
necessary
to
transform
into
this
important
Language: Английский