ChemistrySelect, Journal Year: 2025, Volume and Issue: 10(19)
Published: May 1, 2025
Abstract Oxazole derivatives represent a crucial class of heterocycles with broad applications spanning medicinal chemistry, materials science, and organic synthesis. Their structural versatility biological significance have fueled ongoing efforts to develop efficient sustainable synthetic methodologies. However, despite their importance, the literature on multicomponent synthesis oxazoles remains relatively sparse, necessitating comprehensive review. This review examines diverse, approaches, encompassing three‐ four‐component reactions. The highlights versatility, efficiency, adaptability these methods, underscoring evolution oxazole focus functional group diversity, environmental considerations, scalability. Covering developments from 1990 early 2025, this provides critical overview progress challenges in synthesis, aiming support future drug development advanced materials.
Language: Английский