Halogen cation-promoted and solvent-regulated electrophilic cyclization for the regioselective synthesis of 3-haloquinolines and 3-halospirocyclohexadienones DOI
Jianming Li, Chengxiao Liu, Zihan Zhao

et al.

Organic & Biomolecular Chemistry, Journal Year: 2023, Volume and Issue: 21(11), P. 2440 - 2446

Published: Jan. 1, 2023

A novel approach for the production of halogen cations through reaction halogens with silver ions is described in this paper. On basis, regioselective synthesis 3-haloquinolines and 3-halospirocyclohexadienones realized solvent regulation. The gram-scale compatibility complex substrates demonstrate synthetic potential protocol, which will be an appealing strategy organic synthesis.

Language: Английский

Applications of phenyliodine(III) diacetate in heterocyclic ringformations: An updatefrom 2015 to date DOI
Mohammed Mujahid Alam,

Mohamed Hussien,

Hari Babu Bollikolla

et al.

Journal of Heterocyclic Chemistry, Journal Year: 2023, Volume and Issue: 60(8), P. 1326 - 1355

Published: Jan. 27, 2023

Abstract Diacetoxyiodobenzene ( PhI OAc ) 2 ), commonly referred to as DAIB or phenyliodine( III diacetate PIDA is one of the most frequently used hypervalent iodines employed an oxidizing agent in organic chemistry. In this review, highlighted exclusively relation its applications synthesis involving heterocyclic ring formations and critically in‐depth examined from summer 2015 present with a specific focus on mechanistic pathway.

Language: Английский

Citations

12

Recent progress in metal assisted multicomponent reactions in organic synthesis DOI Creative Commons

Kokila Sakthivel,

R. Gana,

Toshitaka Shoji

et al.

Frontiers in Chemistry, Journal Year: 2023, Volume and Issue: 11

Published: Sept. 8, 2023

To prepare complicated organic molecules, straightforward, sustainable, and clean methodologies are urgently required. Thus, researchers attempting to develop imaginative approaches. Metal-catalyzed multicomponent reactions (MCRs) offer optimal molecular diversity, high atomic efficiency, energy savings in a single reaction step. These versatile protocols often used synthesize numerous natural compounds, heterocyclic medications. Thus far, the majority of metal-catalyzed MCRs under investigation based on metal catalysts such as copper palladium; however, current research is focused developing novel, environmentally friendly catalytic systems. In this regard, study demonstrates effectiveness MCRs. The aim provide an overview for safe application

Language: Английский

Citations

7

Halogenative Annulation Reactions of Alkyne-Tethered N- and O-Containing Arenes: Methods for Accessing Aryl-Fused Halogenated N- and O-Heterocycles DOI
Charnsak Thongsornkleeb, Jumreang Tummatorn, Somsak Ruchirawat

et al.

Synthesis, Journal Year: 2023, Volume and Issue: 55(19), P. 3073 - 3089

Published: June 21, 2023

Abstract Halogenative annulation of alkyne-tethered N- and O-containing arenes represents a general strategy for the construction various halogenated O-heterocycles. The methods employed are useful in producing valuable synthetic building blocks carrying C(sp2)–halide functional groups, which handles, especially cross-coupling reactions myriad other transformations. When alkyne is tethered to heteroatom via an aromatic ring, reaction gives rise aryl-fused heterocycles. In this Short Review, past present halogenative construct O-heterocycles examined, with focus on more recent technologies roles participating halogenating agents. Additionally, future directions age-old, but still very useful, considered. 1 Introduction 2 Synthesis Aryl-Fused Halogenated N-Heterocycles 2.1 5-Membered 2.2 6-Membered 2.3 7-Membered 3 O-Heterocycles 3.1 3.2 3.3 4 Conclusion

Language: Английский

Citations

4

Halogen cation-promoted and solvent-regulated electrophilic cyclization for the regioselective synthesis of 3-haloquinolines and 3-halospirocyclohexadienones DOI
Jianming Li, Chengxiao Liu, Zihan Zhao

et al.

Organic & Biomolecular Chemistry, Journal Year: 2023, Volume and Issue: 21(11), P. 2440 - 2446

Published: Jan. 1, 2023

A novel approach for the production of halogen cations through reaction halogens with silver ions is described in this paper. On basis, regioselective synthesis 3-haloquinolines and 3-halospirocyclohexadienones realized solvent regulation. The gram-scale compatibility complex substrates demonstrate synthetic potential protocol, which will be an appealing strategy organic synthesis.

Language: Английский

Citations

0