Immunomodulatory Bioadhesive Technologies

Biomaterials, Journal Year: 2025, Volume and Issue: unknown, P. 123274 - 123274

Published: March 1, 2025

Bioadhesives have found significant use in medicine and engineering, particularly for wound care, tissue surgical applications. Compared to traditional closure methods such as sutures staples, bioadhesives offer advantages, including reduced damage, enhanced healing, ease of implementation. Recent progress highlights the synergy immunoengineering strategies, leading immunomodulatory capable modulating immune responses at local sites where are applied. They foster favorable therapeutic outcomes inflammation wounds implants or improve cancer therapy efficacy. The dual functionalities bioadhesion immunomodulation benefit management, regeneration, implantable medical devices, post-surgical management. This review delves into interplay between immunomodulation, highlighting mechanobiological coupling involved. Key areas focus include modulation through chemical physical well application these healing treatment. Discussed remaining challenges achieving long-term stability effectiveness, necessitating further research fully harness clinical potential bioadhesives.

Language: Английский

Emerging roles of mechanically activated ion channels in autoimmune disease

Autoimmunity Reviews, Journal Year: 2025, Volume and Issue: 24(7), P. 103813 - 103813

Published: April 7, 2025

Language: Английский