Science Advances,
Journal Year:
2022,
Volume and Issue:
8(50)
Published: Dec. 14, 2022
Cortical
variations
in
cytoarchitecture
form
a
sensory-fugal
axis
that
shapes
regional
profiles
of
extrinsic
connectivity
and
is
thought
to
guide
signal
propagation
integration
across
the
cortical
hierarchy.
While
neuroimaging
work
has
shown
this
constrains
local
properties
human
connectome,
it
remains
unclear
whether
also
asymmetric
signaling
arises
from
higher-order
topology.
Here,
we
used
network
control
theory
examine
amount
energy
required
propagate
dynamics
axis.
Our
results
revealed
an
asymmetry
energy,
indicating
bottom-up
transitions
were
easier
complete
compared
top-down.
Supporting
analyses
demonstrated
asymmetries
underpinned
by
connectome
topology
wired
support
efficient
signaling.
Lastly,
found
correlated
with
differences
communicability
intrinsic
neuronal
time
scales
lessened
throughout
youth.
show
variation
may
formation
macroscopic
Trends in Cognitive Sciences,
Journal Year:
2024,
Volume and Issue:
28(4), P. 352 - 368
Published: Jan. 9, 2024
To
explain
how
the
brain
orchestrates
information-processing
for
cognition,
we
must
understand
information
itself.
Importantly,
is
not
a
monolithic
entity.
Information
decomposition
techniques
provide
way
to
split
into
its
constituent
elements:
unique,
redundant,
and
synergistic
information.
We
review
disentangling
redundant
interactions
redefining
our
understanding
of
integrative
function
neural
organisation.
navigates
trade-offs
between
redundancy
synergy,
converging
evidence
integrating
structural,
molecular,
functional
underpinnings
synergy
redundancy;
their
roles
in
cognition
computation;
they
might
arise
over
evolution
development.
Overall,
provides
guiding
principle
informational
architecture
cognition.
Science Advances,
Journal Year:
2023,
Volume and Issue:
9(2)
Published: Jan. 13, 2023
Identifying
the
functional
specialization
of
brain
has
moved
from
using
cognitive
tasks
and
resting
state
to
ecological
relevant,
naturalistic
movies.
We
leveraged
a
large-scale
neuroimaging
dataset
directly
investigate
hierarchical
reorganization
activity
when
watching
films
compared
performing
seven
resting.
A
thermodynamics-inspired
whole-brain
model
paradigm
revealed
generative
underlying
mechanisms
for
changing
balance
in
causal
interactions
between
regions
different
conditions.
Paradoxically,
hierarchy
is
flatter
movie-watching,
level
nonreversibility
significantly
smaller
comparison
both
rest
tasks,
where
latter
turn
have
highest
levels
nonreversibility.
The
were
by
model-based
effective
connectivity
(GEC).
Naturalistic
could
therefore
provide
fast
convenient
way
measure
important
changes
GEC
(integrating
anatomical
connectivity)
found
in,
example,
neuropsychiatric
disorders.
Overall,
this
study
demonstrates
benefits
moving
toward
more
neuroscience.
Nature Communications,
Journal Year:
2024,
Volume and Issue:
15(1)
Published: Jan. 4, 2024
It
is
widely
believed
the
brain-inspired
spiking
neural
networks
have
capability
of
processing
temporal
information
owing
to
their
dynamic
attributes.
However,
how
understand
what
kind
mechanisms
contributing
learning
ability
and
exploit
rich
properties
satisfactorily
solve
complex
computing
tasks
in
practice
still
remains
be
explored.
In
this
article,
we
identify
importance
capturing
multi-timescale
components,
based
on
which
a
multi-compartment
model
with
dendritic
heterogeneity,
proposed.
The
enables
dynamics
by
automatically
heterogeneous
timing
factors
different
branches.
Two
breakthroughs
are
made
through
extensive
experiments:
working
mechanism
proposed
revealed
via
an
elaborated
XOR
problem
analyze
feature
integration
at
levels;
comprehensive
performance
benefits
over
ordinary
achieved
several
benchmarks
for
speech
recognition,
visual
electroencephalogram
signal
robot
place
shows
best-reported
accuracy
compactness,
promising
robustness
generalization,
high
execution
efficiency
neuromorphic
hardware.
This
work
moves
significant
step
toward
real-world
applications
appropriately
exploiting
biological
observations.
Translational Psychiatry,
Journal Year:
2024,
Volume and Issue:
14(1)
Published: July 5, 2024
Abstract
Major
depressive
disorder
(MDD)
is
characterized
by
a
multitude
of
psychopathological
symptoms
including
affective,
cognitive,
perceptual,
sensorimotor,
and
social.
The
neuronal
mechanisms
underlying
such
co-occurrence
remain
yet
unclear.
Rather
than
linking
localizing
single
to
specific
regions
or
networks,
this
perspective
proposes
more
global
dynamic
topographic
approach.
We
first
review
recent
findings
on
brain
activity
changes
during
both
rest
task
states
in
MDD
showing
reorganization
with
shift
from
unimodal
transmodal
regions.
Next,
we
out
two
candidate
that
may
underlie
mediate
abnormal
uni-/transmodal
topography,
namely
shifts
shorter
longer
timescales
abnormalities
the
excitation-inhibition
balance.
Finally,
show
how
relates
various
their
co-occurrence.
This
amounts
what
describe
as
‘Topographic
reorganization’
which
extends
our
earlier
‘Resting
state
hypothesis
depression’
complements
other
models
MDD.
Neuroscience & Biobehavioral Reviews,
Journal Year:
2022,
Volume and Issue:
138, P. 104715 - 104715
Published: May 30, 2022
As
we
move
through
the
world,
natural
and
built
environments
implicitly
guide
behavior
by
appealing
to
certain
sensory
motor
dynamics.
This
process
can
be
motivated
automatic
attention
environmental
features
that
resonate
with
specific
sensorimotor
responses.
review
aims
at
providing
a
psychobiological
framework
describing
how
lead
automated
responses
defined
neurophysiological
mechanisms
underlying
attention.
Through
use
of
processes
in
subsets
cortical
structures,
goal
this
is
describe
on
neuronal
level
functional
link
between
designed
environment
By
distinguishing
elaborate
employs
for
adaptation.
realized
thalamo-cortical
network
integrating
aspects
behavior.
We
highlight
transthalamic
transmission
from
an
Enactive
predictive
perspective
recent
studies
effectively
modulated
systematically
manipulating
features.
end
suggesting
promising
combination
neuroimaging
computational
analysis
future
studies.
Trends in Neurosciences,
Journal Year:
2023,
Volume and Issue:
46(5), P. 377 - 393
Published: March 27, 2023
Crossmodal
plasticity
is
a
textbook
example
of
the
ability
brain
to
reorganize
based
on
use.
We
review
evidence
from
auditory
system
showing
that
such
reorganization
has
significant
limits,
dependent
pre-existing
circuitry
and
top-down
interactions,
extensive
often
absent.
argue
does
not
support
hypothesis
crossmodal
responsible
for
closing
critical
periods
in
deafness,
instead
represents
neuronal
process
dynamically
adaptable.
evaluate
changes
both
developmental
adult-onset
which
start
as
early
mild-moderate
hearing
loss
show
reversibility
when
restored.
Finally,
appear
affect
preconditions
successful
restoration.
Given
its
dynamic
versatile
nature,
we
describe
how
this
can
be
exploited
improving
clinical
outcomes
after
neurosensory
