NEUROBIOLOGICAL AND PSYCHOPHYSIOLOGICAL DIFFERENCES OF VISUAL WORKING MEMORY FUNCTIONING IN RADAR STATION OPERATORS DOI Open Access
O.I. Podkovka,

Mykola Makarchuk,

Наталя Філімонова

et al.

Fìzìologìčnij žurnal, Journal Year: 2023, Volume and Issue: 69(6), P. 22 - 32

Published: Nov. 10, 2023

Operators are often subjected to a high working memory load as far any possibly useful information must always be available and presented the operator. Thus, we assumed that they may have developed adaptations in mechanisms of realization help them more efficient overload conditions. Our aim was define differences visual functioning radar station operators (RSO) other military profession representatives. For this purpose, parallel with performance original computer tests for identification, which had two levels complexity, recorded an electroencephalogram subsequent coherent LORETA analysis electrocardiogram determining stress index regulatory systems. It found reaction time, well number errors both tests, didn`t differ significantly groups. At same control group higher θ-band connections frontal lobe could indicate level mental emotional involvement. This assumption confirmed by dynamic group. showed RSO group, degree fronto-parietal, cingulo-opercular networks, cuneus precuneus involvement at from very first tasks, while it increased task is evidence adaptive changes RSO, due successfully cope overload.

Language: Английский

Serotonin Inhibition of Claustrum Projection Neurons: Ionic Mechanism, Receptor Subtypes and Consequences for Claustrum Computation DOI Creative Commons
Kelly L.L. Wong, Martin Graf,

George J. Augustine

et al.

Cells, Journal Year: 2024, Volume and Issue: 13(23), P. 1980 - 1980

Published: Nov. 29, 2024

The claustrum is a small but densely interconnected brain structure that innervated by axons containing serotonin (5-HT), neuromodulator has been implicated in control of sleep and the actions psychedelic drugs. However, little known about how 5-HT influences claustrum. We have combined whole-cell patch-clamp measurements ionic currents, flash photolysis, receptor pharmacology to characterize responses individual claustral projection neurons (PNs) mouse slices. Serotonin application elicited long-lasting outward current PNs. This was due an increase membrane permeability K+ ions mediated mainly type 1A (5-HTR-1A). 5-HT-induced hyperpolarized, thereby inhibited, PNs reducing action potential firing. Focal uncaging revealed inhibitory 5-HTR-1As were located at both soma dendrites conclude creates net inhibition claustrum, should decrease sensitivity excitatory input from other areas contribute brain.

Language: Английский

Citations

1

Mapping common and distinct brain correlates among cognitive flexibility tasks: concordant evidence from meta-analyses DOI Creative Commons

Zhanna Vladimirovna Chuikova,

Andrei A. Filatov,

Annemarie M. E. Faber

et al.

Brain Imaging and Behavior, Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 29, 2024

Cognitive flexibility allows individuals to switch between different tasks, strategies, or ideas; an ability that is important for everyday life. The Wisconsin card sorting test (WCST) and task switching paradigm (TSP) are popular measures of cognitive flexibility. Although both tasks require switching, the TSP requires participants memorize rules retrieve them when they view a cue (rule-retrieval), whereas classic WCST discover rule via trial-and-error (rule-discovery). Many functional magnetic resonance imaging studies have examined brain responses these tasks. Extant meta-analyses show concordance in activation widespread set areas including frontal, parietal, cingulate cortices. Critically, past not specifically correlates associated with derivation (i.e., rule-discovery vs. rule-retrieval) We examine first time common distinct WCST) rule-retrieval TSP), as well subtypes using quantitative meta-analyses. analyzed data from 69 eligible articles total 1617 young-adult participants. Conjunction results fronto-parietal predominantly left hemisphere. Contrast analyses required increased involvement multiple cortical subcortical regions such frontopolar (Brodmann Area 10), insular cortex, thalamus caudate nucleus right No significant differences were observed among three, sub-types. propose neuroanatomical model discuss theoretical practical applications.

Language: Английский

Citations

1

Brain-consistent architecture for imagination DOI Creative Commons
Hiroshi Yamakawa, Ayako Fukawa, Ikuko Eguchi Yairi

et al.

Frontiers in Systems Neuroscience, Journal Year: 2024, Volume and Issue: 18

Published: Aug. 20, 2024

Imagination represents a pivotal capability of human intelligence. To develop human-like artificial intelligence, uncovering the computational architecture pertinent to imaginative capabilities through reverse engineering brain's functions is essential. The existing Structure-Constrained Interface Decomposition (SCID) method, leverages anatomical structure brain extract architecture. However, its efficacy limited narrow regions, making it unsuitable for realizing function imagination, which involves diverse areas such as neocortex, basal ganglia, thalamus, and hippocampus.

Language: Английский

Citations

0

Claustrum modulation drives altered prefrontal cortex dynamics and connectivity DOI Creative Commons

Ryan Zahacy,

Yonglie Ma,

Ian R. Winship

et al.

Communications Biology, Journal Year: 2024, Volume and Issue: 7(1)

Published: Nov. 22, 2024

This study delves into the claustrum's role in modulating spontaneous and sensory-evoked network activity across cortical regions. Using mesoscale calcium imaging Gi Gq DREADDs anesthetized mice, we show that decreasing claustral enhances prefrontal activity, while activation reduces activity. claustrum modulation also caused changes to brain's large-scale functional networks, emphasizing ability influence long-range connectivity cortex. Claustrum inhibition increased local coupling between frontal cortex areas, but reduced correlation anterior medial regions lateral/posterior regions, enhancing responses visual These findings indicate can participate orchestrating neural communication through of insights deepen our understanding impact on connectivity, dynamics, sensory processing, positioning as a key node dynamics. Chemogenetic claustro-cortical neurons alters measured by fluorescence mice.

Language: Английский

Citations

0

NEUROBIOLOGICAL AND PSYCHOPHYSIOLOGICAL DIFFERENCES OF VISUAL WORKING MEMORY FUNCTIONING IN RADAR STATION OPERATORS DOI Open Access
O.I. Podkovka,

Mykola Makarchuk,

Наталя Філімонова

et al.

Fìzìologìčnij žurnal, Journal Year: 2023, Volume and Issue: 69(6), P. 22 - 32

Published: Nov. 10, 2023

Operators are often subjected to a high working memory load as far any possibly useful information must always be available and presented the operator. Thus, we assumed that they may have developed adaptations in mechanisms of realization help them more efficient overload conditions. Our aim was define differences visual functioning radar station operators (RSO) other military profession representatives. For this purpose, parallel with performance original computer tests for identification, which had two levels complexity, recorded an electroencephalogram subsequent coherent LORETA analysis electrocardiogram determining stress index regulatory systems. It found reaction time, well number errors both tests, didn`t differ significantly groups. At same control group higher θ-band connections frontal lobe could indicate level mental emotional involvement. This assumption confirmed by dynamic group. showed RSO group, degree fronto-parietal, cingulo-opercular networks, cuneus precuneus involvement at from very first tasks, while it increased task is evidence adaptive changes RSO, due successfully cope overload.

Language: Английский

Citations

1