Magnesium and Longevity
Published: Nov. 7, 2024
Magnesium
(Mg)
is
not
prominent
among
the
list
of
well
known
anti-aging
agents.
Yet
signs
and
symptoms
aging
mimic
those
Mg
deficiency.
required
for
over
800
enzymatic
reactions
(as
2022).
This
review
does
correlate
status
with
clinical
data
on
agents
linked
to
longevity.
The
approach
physiologic
highlights
specific
dependent
by
these
longevity
biomarkers.
Many
share
common
pathways
extend
healthspan.
a
cofactor
in
synthesis
vitamin
D
melatonin
activation
six
eight
B
vitamins.
It
all
CYP450
enzymes.
directly
responsible
appropriate
methylation
proteins
DNA,
which
control
epigenome.
MTHFR
(methylenetetrahydrofolate
reductase)
677T
allele
that
compromises
present
majority
Americans.
Aberrant
predicts
severity
Covid-19
its
persistence
into
long
Covid.
silent
benefactor
may
indirectly
link
agents,
but
only
if
viewed
context
calcium
(Ca),
i.e.,
Ca:Mg.
Both
compete
same
receptor.
To
fully
exploit
sufficient
required.
pertinent
physiology
presented.
Language: Английский
Water-soluble components of ten Brazilian desi and kabuli chickpeas and their potential for health-promoting plant-based beverages.
Food Chemistry Advances,
Journal Year:
2025,
Volume and Issue:
unknown, P. 100955 - 100955
Published: March 1, 2025
Language: Английский
A rat pup model: Investigate the digestibility and absorption characteristics of human, bovine and camel lactoferrin
Food Bioscience,
Journal Year:
2025,
Volume and Issue:
unknown, P. 106507 - 106507
Published: April 1, 2025
Language: Английский
High methionine intake alters gut microbiota and lipid profile and leads to liver steatosis in mice
Food & Function,
Journal Year:
2024,
Volume and Issue:
15(15), P. 8053 - 8069
Published: Jan. 1, 2024
Methionine
is
an
important
sulfur-containing
amino
acid.
Health
effects
of
both
methionine
restriction
(MR)
and
supplementation
(MS)
have
been
studied.
This
study
aimed
to
investigate
the
impact
a
high-methionine
diet
(HMD)
(1.64%
methionine)
on
gut
liver
functions
in
mice
through
multi-omic
analyses.
Hepatic
steatosis
compromised
barrier
function
were
observed
fed
HMD.
RNA-sequencing
(RNA-seq)
analysis
gene
expression
patterns
revealed
upregulation
lipid
synthesis
degradation
pathways,
cholesterol
metabolism
inflammation-related
nucleotide-binding
oligomerization
domain
(NOD)-like
receptor
signaling
pathway.
Metagenomic
sequencing
cecal
content
demonstrated
shift
microbial
composition
with
increased
abundance
opportunistic
pathogens
up-regulated
lipopolysaccharide
(LPS)
biosynthesis
Metabolomic
showed
altered
profile
level
bioactive
lipids,
including
docosahexaenoic
acid
(DHA),
eicosapentaenoic
(EPA),
palmitoylethanolamide
(PEA),
linoleoyl
ethanolamide
(LEA)
arachidonoyl
(AEA),
that
carry
anti-inflammatory
significantly
reduced
Correlation
microbiota
was
highly
associated
content.
In
conclusion,
this
suggested
HMD
exerted
negative
impacts
liver,
adequate
amount
intake
should
be
carefully
determined
ensure
normal
physiological
without
causing
adverse
effects.
Language: Английский
Magnesium and Longevity
Qeios,
Journal Year:
2024,
Volume and Issue:
6(11)
Published: Nov. 12, 2024
Magnesium
(Mg)
is
not
prominent
among
the
list
of
well
known
anti-aging
agents.
Yet
signs
and
symptoms
aging
mimic
those
Mg
deficiency.
required
for
nearly
a
thousand
enzymatic
reactions.
This
narrative
review
does
correlate
status
with
clinical
data
on
agents
linked
to
longevity.
The
approach
more
novel
highlights
specific
dependent
physiologic
reactions
by
these
longevity
biomarkers.
Many
share
common
pathways
extend
healthspan.
cofactor
in
synthesis
vitamin
D
melatonin
activation
six
eight
B
vitamins.
It
all
CYP450
enzymes.
directly
responsible
appropriate
methylation
proteins
DNA,
which
control
epigenome.
MTHFR
(methylenetetrahydrofolate
reductase)
677T
allele
that
compromises
present
majority
Americans.
Aberrant
predicts
severity
Covid-19
its
persistence
into
long
Covid.
silent
benefactor
may
indirectly
link
agents,
but
only
if
viewed
context
calcium
(Ca),
i.e.,
Ca:Mg.
Both
compete
same
receptor.
To
fully
exploit
sufficient
required.
pertinent
physiology
presented,
although
cause
effect
awaits
publication
supporting
data.
Language: Английский