Multilamellar nanocochleates as novel co-encapsulation systems for enhancement of the physicochemical properties and controlled release of astaxanthin and phycocyanin DOI
Mohammad Molaveisi,

Li Li,

Zhao Ya

et al.

Food Chemistry, Journal Year: 2025, Volume and Issue: unknown, P. 144741 - 144741

Published: May 1, 2025

Language: Английский

Lipid Nanoparticles: Formulation, Production Methods and Characterization Protocols DOI Creative Commons
Fernanda Luísa Lüdtke, Thaís Jordânia Silva, Mayanny Gomes da Silva

et al.

Foods, Journal Year: 2025, Volume and Issue: 14(6), P. 973 - 973

Published: March 12, 2025

Lipid nanoparticles (LNs) have emerged as advanced lipid-based delivery systems, offering an effective approach for encapsulating and protecting lipid-soluble bioactive compounds, increasing their bioavailability. Solid Nanoparticles (SLNs) Nanostructured Carriers (NLCs) are particularly promising compound entrapment. However, to fully exploit potential, it is crucial carefully select the appropriate lipid matrices emulsifiers. This review offers a comprehensive, up-to-date examination, considering studies published in last 15 years, of chemical, physical, structural characteristics lipids employed LN production, focusing on key components formulations: matrices, emulsifiers, compounds. In addition, provides in-depth analysis production methods, drawing insights from latest scientific literature, emphasizes most important characterization techniques LNs. Key parameters, including particle size (PS), zeta potential (ZP), crystallinity, thermal behavior, morphology, entrapment efficiency (EE), load capacity (LC), physical stability, discussed. Ultimately, this aims identify critical factors successful stable LNs that efficiently encapsulate deliver highlighting significant applications food systems.

Language: Английский

Citations

0
Preparation and Characterization of Vitamin D3-Based Binary Amorphous Systems DOI Creative Commons

Xiaoshuo Zhao,

Xuemei Wang, Qian Wu

et al.

Foods, Journal Year: 2025, Volume and Issue: 14(8), P. 1321 - 1321

Published: April 11, 2025

Vitamin D3 (VD3) is an essential nutrient for human health that plays a key role in bone and immune regulation. However, VD3 deficiency has become common issue worldwide due to insufficient daily intake inadequate conversion from sunlight exposure. The relatively poor aqueous solubility of one the major challenges development oral supplements functional foods, since it usually results low absorption. In this study, total 11 potential binary systems were prepared by solvent evaporation. amorphous system L-arginine (ARG) been found be most promising system, VD3–ARG can significantly improve VD3, with 80-fold enhancement relative neat crystalline VD3. amorphization was confirmed morphology observed. Molecular interactions between ARG mainly attributed hydrogen bonding, three specific bonding sites revealed. Furthermore, superior dissolution behavior observed compared A higher saturation level achieved maintained desired period. Overall, study developed formulation strategy enhance which further applied foods supplements.

Language: Английский

Citations

0
A Self-Nanoemulsifying Drug Delivery System for Vitamin D3: Design, Optimization and Pharmacokinetic Evaluation DOI

Mariyambibi A. Mandarawala,

Ashok Mahajan, Shailesh Koradia

et al.

Journal of Pharmaceutical Innovation, Journal Year: 2025, Volume and Issue: 20(3)

Published: April 30, 2025

Language: Английский

Citations

0
Multilamellar nanocochleates as novel co-encapsulation systems for enhancement of the physicochemical properties and controlled release of astaxanthin and phycocyanin DOI
Mohammad Molaveisi,

Li Li,

Zhao Ya

et al.

Food Chemistry, Journal Year: 2025, Volume and Issue: unknown, P. 144741 - 144741

Published: May 1, 2025

Language: Английский

Citations

0