Overcoming drug resistance through extracellular vesicle-based drug delivery system in cancer treatment DOI Open Access
Long Tai Zheng,

R. S. F. Chang,

B. Liang

et al.

Cancer Drug Resistance, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 12, 2024

Drug resistance is a major challenge in cancer therapy that often leads to treatment failure and disease relapse. Despite advancements chemotherapeutic agents targeted therapies, cancers develop drug resistance, making these treatments ineffective. Extracellular vesicles (EVs) have gained attention for their potential applications delivery because of natural origin, biocompatibility, ability cross biological barriers. Using the unique properties EVs could enhance accumulation at target sites, minimize systemic toxicity, precisely specific cells. Here, we discuss characteristics functionalization EVs, mechanisms engineered overcome resistance. This review provides comprehensive overview EV-based systems overcoming We highlight revolutionize offer promising strategies more effective modalities.

Language: Английский

Advances of transdermal drug delivery system based on extracellular vesicles DOI

Haoqiang Qin,

Min Zhang, Hao Wang

et al.

Journal of Drug Delivery Science and Technology, Journal Year: 2025, Volume and Issue: unknown, P. 106647 - 106647

Published: Jan. 1, 2025

Language: Английский

Citations

0
Extracellular vesicles as natural nanocarriers: From in vitro engineering to in situ generation in cancer therapy DOI
Teng Zhang,

Zimai Liu,

Yuanyuan Wei

et al.

Chemical Engineering Journal, Journal Year: 2025, Volume and Issue: unknown, P. 161653 - 161653

Published: March 1, 2025

Language: Английский

Citations

0
Overcoming drug resistance through extracellular vesicle-based drug delivery system in cancer treatment DOI Open Access
Long Tai Zheng,

R. S. F. Chang,

B. Liang

et al.

Cancer Drug Resistance, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 12, 2024

Drug resistance is a major challenge in cancer therapy that often leads to treatment failure and disease relapse. Despite advancements chemotherapeutic agents targeted therapies, cancers develop drug resistance, making these treatments ineffective. Extracellular vesicles (EVs) have gained attention for their potential applications delivery because of natural origin, biocompatibility, ability cross biological barriers. Using the unique properties EVs could enhance accumulation at target sites, minimize systemic toxicity, precisely specific cells. Here, we discuss characteristics functionalization EVs, mechanisms engineered overcome resistance. This review provides comprehensive overview EV-based systems overcoming We highlight revolutionize offer promising strategies more effective modalities.

Language: Английский

Citations

1