Folate metabolism in myelofibrosis: a missing key?
Giacomo Maria Cerreto,
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Giulia Pozzi,
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Samuele Cortellazzi
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et al.
Annals of Hematology,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Jan. 23, 2025
Language: Английский
The Protective Role of Folic Acid in Biochemical and Histopathological Changes Induced by Azithromycin in the Livers of Pregnant Albino Rats
Safaa M. Hanafy,
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Soha S. Zakaria
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Medicina,
Journal Year:
2025,
Volume and Issue:
61(3), P. 415 - 415
Published: Feb. 27, 2025
Background
and
Objectives:
We
evaluated
the
impact
of
second-generation
macrolide
azithromycin
on
pregnant
albino
rats’
livers
assessed
protective
role
folic
acid.
Materials
Methods:
For
this
study,
forty
rats
were
treated
then
examined.
Forty
divided
into
four
equal
groups
(I–IV).
In
Group
I,
each
rat
was
gavaged
with
1
mL
distilled
water
day
16
pregnancy,
0.5
from
pregnancy
to
20.
II,
0.45
containing
9
mcg
acid
17
III,
mg
16th
day,
4.5
IV,
At
end
experiments,
blood
samples
studied
subjected
biochemical,
histological,
morphometric
analysis.
Results:
Azithromycin
induced
pathological
changes
in
livers,
as
evidenced
by
disturbed
lobular
architecture,
cytoplasmic
vacuoles,
deeply
stained
hepatic
nuclei,
elevated
liver
enzymes.
The
co-administration
ameliorated
most
changes.
Conclusions:
caused
alterations
rats,
co-supplementation
is
encouraged,
minimize
these
Language: Английский
Bibliometric Analysis and a Call for Increased Rigor in Citing Scientific Literature: Folic Acid Fortification and Neural Tube Defect Risk as an Example
Brynne Boeck,
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Cara J. Westmark
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Nutrients,
Journal Year:
2024,
Volume and Issue:
16(15), P. 2503 - 2503
Published: Aug. 1, 2024
The
health
benefits
of
vitamin
B9
(folate)
are
well
documented,
particularly
in
regard
to
neural
tube
defects
during
pregnancy;
however,
much
remains
be
learned
regarding
the
effects
and
risks
consuming
folic
acid
supplements
foods
fortified
with
acid.
In
2020,
our
laboratory
conducted
a
population-based
analysis
Food
Fortification
Initiative
(FFI)
dataset
determine
strength
evidence
prevalence
(NTD)
at
national
level
response
mandatory
fortification
cereal
grains
We
found
very
weak
correlation
between
NTDs
irrespective
grain
(wheat,
maize,
or
rice).
strong
linear
relationship
reduced
higher
socioeconomic
status
(SES).
Our
paper
incited
debate
on
proper
statistics
employ
for
population-level
data.
Subsequently,
there
has
been
large
number
erroneous
citations
original
work.
objective
here
was
conduct
bibliometric
quantitate
accuracy
Murphy
Westmark's
publication
entitled,
"Folic
Acid
Neural
Tube
Defect
Risk:
Analysis
Dataset".
70%
inaccuracy
rate.
These
findings
highlight
dire
need
increased
rigor
citing
scientific
literature,
biomedical
research
that
directly
impacts
public
policy.
Language: Английский