Theoretical study of the molecular aspect of the suspected novichok agent A234 of the Skripal poisoning

Royal Society Open Science, Journal Year: 2019, Volume and Issue: 6(2), P. 181831 - 181831

Published: Feb. 1, 2019

Novichoks are the suspected nerve agents in March 2018 Skripal poisoning. In this context, novichok agent A234 (chemical structure proposed by Mirzayanov) was studied using computational methods to shed light on its molecular, electronic, spectroscopic, thermodynamic and toxicity parameters as well potential thermal hydrolysis degradation pathways. The poisoning action antidote of were also investigated. Some these compared three common G- V-series agents, namely GB, VR VX. research findings should be useful towards detection, development antidotes destruction A234.

Language: Английский

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Pesticide Poisoning and the Use of Personal Protective Equipment (PPE) in Indonesian Farmers

Journal of Environmental and Public Health, Journal Year: 2020, Volume and Issue: 2020, P. 1 - 7

Published: Jan. 21, 2020

This study aimed to investigate the poisoning symptoms occurring in pesticide-exposed farmers. was conducted a red onion farming center area Wanasari Subdistrict, Brebes, Indonesia, from May June 2018. designed as descriptive study. The significance value of p<0.005 showed that variable correlated with health problems, including excessive fatigue (p = 0.041), saliva id="M3">p 0.006), hard breathing id="M4">p 0.021), frequent urination id="M5">p 0.047), blurred vision id="M6">p 0.059), dizziness id="M7">p 0.032), and finger pain id="M8">p 0.007). id="M9">p<0.005) 0.000 use personal protective equipment problems. Based on odds ratio 1.137, 95% confidence interval 0.042–0.444 meant risk factor results 89.2% farmers who used were categorized healthy group.

Language: Английский

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Chlorpyrifos pesticide promotes oxidative stress and increases inflammatory states in BV-2 microglial cells: A role in neuroinflammation

Chemosphere, Journal Year: 2021, Volume and Issue: 278, P. 130417 - 130417

Published: March 29, 2021

Language: Английский

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Pesticide Pollution: Detrimental Outcomes and Possible Mechanisms of Fish Exposure to Common Organophosphates and Triazines

Journal of Xenobiotics, Journal Year: 2022, Volume and Issue: 12(3), P. 236 - 265

Published: Sept. 2, 2022

Pesticides are well known for their high levels of persistence and ubiquity in the environment, because capacity to bioaccumulate disrupt food chain, they pose a risk animals humans. With focus on organophosphate triazine pesticides, present review aims describe current state knowledge regarding spatial distribution, bioaccumulation, mode action frequently used pesticides. We discuss processes by which pesticides active residues accumulated bioconcentrated fish, as toxic mechanisms involved, including biological redox activity, immunotoxicity, neuroendocrine disorders, cytotoxicity, is manifested oxidative stress, lysosomal mitochondrial damage, inflammation, apoptosis/autophagy. also explore potential research strategies close gaps our understanding toxicity environmental assessment

Language: Английский

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Bimodal ratiometric fluorescence and colorimetric sensing of paraoxon based on trifunctional Ce,Tb co-coordinated polymers

Sensors and Actuators B Chemical, Journal Year: 2022, Volume and Issue: 360, P. 131616 - 131616

Published: Feb. 23, 2022

Language: Английский

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