
Scientific Reports, Journal Year: 2020, Volume and Issue: 10(1)
Published: Oct. 6, 2020
Abstract The current study was carried out on dominant fish Oreochromis niloticus and water collected from the polluted Yamuna River, Agra, India. heavy metals in water, recorded as follows: Fe > Mn Zn Cu Ni Cr Cd all were found to be above prescribed limits. According metal pollution index, exposed muscle (49.86), kidney (47.68) liver (45.26) have been higher bioaccumulation. blood biochemical analysis of O. indicated significant increase activities aspartate aminotransferase (+ 343.5%), alkaline phosphatase 673.6%), alanine 309.1%), creatinine 494.3%) over reference. However, a decrease albumin (A): globulins (G) ratio (− 87.86%) observed. Similarly, also showed total leucocyte count 121%), differential count, respiratory burst 1175%), nitric oxide synthase 420%). histological examination tissue injury. Moreover, micronuclei (0.95%), shaped nuclei (1.2%), lobed (0.6%) along with DNA damage form mean tail length (20.7 µm) (16.5 observed . Potential health risk assessments based estimated daily intake, target hazard quotient, cancer risks associated consumption these contaminated fishes. In conclusion, present that exposure can alter immunological response; induce histopathological alterations studied fish. this or could serious impact human health.
Language: Английский