Drug
residues
that
contaminate
food
and
water
represent
a
serious
concern
for
human
health,
since
their
irrational
use
is
constantly
increasing
the
amplitude
of
exposure.
Multiple
sources
contribute
to
overall
exposure
contaminants,
including
agriculture,
domestic
use,
personal,
public,
veterinary
healthcare,
possible
origin
contamination.
In
this
review,
we
focus
on
crop
pesticides
drug
because
extensive
in
modern
agriculture
farming,
which
ensures
production
security
ever-growing
population
around
world.
We
discuss
with
respect
worldwide
distribution
impacts,
special
attention
harmful
effects
reproduction
embryo
development,
as
well
link
epigenetic
alterations,
leading
intergenerational
transgenerational
diseases.
Among
most
commonly
implicated
causing
such
disorders
are
organophosphates,
glyphosate
antibiotics,
tetracyclines
being
frequently
reported.
This
review
highlights
importance
finding
new
management
strategies
drugs.
Moreover,
due
still
limited
knowledge
inter-
these
underlie
need
strengthen
research
field,
so
better
clarify
specific
each
contaminant
long-term
impact.
Comprehensive Reviews in Food Science and Food Safety,
Journal Year:
2024,
Volume and Issue:
24(1)
Published: Dec. 16, 2024
Abstract
Food
packaging
(FP)
is
essential
for
preserving
food
quality,
safety,
and
extending
shelf‐life.
However,
growing
concerns
about
the
environmental
health
impacts
of
conventional
materials,
particularly
per‐
polyfluoroalkyl
substances
(PFAS)
microplastics,
are
driving
a
major
transformation
in
FP
design.
PFAS,
synthetic
compounds
with
dual
hydro‐
lipophobicity,
have
been
widely
employed
materials
(FPMs)
to
impart
desirable
water
grease
repellency.
PFAS
bioaccumulate
human
body
linked
multiple
effects,
including
immune
system
dysfunction,
cancer,
developmental
problems.
The
detection
microplastics
various
FPMs
has
raised
significant
regarding
their
potential
migration
into
subsequent
ingestion.
This
comprehensive
review
examines
current
landscape
FPMs,
functions,
physicochemical
properties
put
perspective
why
there
widespread
use
FPMs.
then
addresses
challenges
posed
by
emphasizing
urgent
need
sustainable
bio‐based
alternatives.
We
highlight
promising
advancements
renewable
plant‐derived
polysaccharides,
proteins,
waxes,
as
well
recycled
upcycled
materials.
integration
these
active
systems
also
examined,
indicating
innovations
oxygen
scavengers,
moisture
absorbers,
antimicrobial
packaging.
concludes
identifying
key
research
gaps
future
directions,
life
cycle
assessments
strategies
improve
scalability
cost‐effectiveness.
As
industry
evolves,
holistic
approach
considering
impact,
functionality,
consumer
acceptance
will
be
crucial
developing
truly
solutions.
Biomedicines,
Journal Year:
2024,
Volume and Issue:
12(6), P. 1255 - 1255
Published: June 5, 2024
Background.
Perfluorinated
alkyl
acids
(PFAAs)
are
persistent
organic
pollutants
affected
by
BMI
and
ethnicity,
with
contradictory
reports
of
association
vitamin
D
deficiency.
Methods.
Twenty-nine
Caucasian
women
non-obese
polycystic
ovary
syndrome
(PCOS)
age-
BMI-matched
control
(n
=
30)
were
recruited.
Paired
serum
samples
analyzed
for
PFAAs
13)
using
high-performance
liquid
chromatography–tandem
mass
spectrometry.
Tandem
spectrometry
determined
levels
25(OH)D3
the
active
1,25(OH)2D3.
Results.
Women
without
PCOS
did
not
differ
in
age,
weight,
insulin
resistance,
or
systemic
inflammation
(C-reactive
protein
differ),
but
free
androgen
index
was
increased.
Four
detected
all
samples:
perfluorooctane
sulfonic
acid
(PFOS),
perfluorooctanoic
(PFOA),
perfluorononanoic
(PFNA),
perfluorohexane
(PFHxS).
Serum
PFOS
higher
versus
controls
(geometric
mean
[GM]
3.9
vs.
3.1
ng/mL,
p
<
0.05).
Linear
regression
modeling
showed
that
elevated
PFHxS
had
odds
a
lower
(OR:
2.919,
95%
CI
0.82–5.75,
0.04).
Vitamin
between
cohorts
correlate
any
PFAAs,
either
alone
when
groups
combined.
When
stratified
into
sufficiency
(>20
ng/mL)
deficiency
(<20
ng/mL),
no
correlation
seen.
Conclusions.
While
analyses
findings
here
exploratory
light
relatively
small
recruitment
numbers,
BMI,
resistance
accounted
for,
do
appear
to
be
related
1,25(OH)2D3
this
population,
nor
they
associated
deficiency,
suggesting
future
studies
must
account
these
factors
analysis.
