Pattern, severity, and treatment outcomes in acute poisoning patients admitted to the Saint Peter Specialized Hospital Toxicology Center in Addis Ababa, Ethiopia, 2023: a retrospective study

Frontiers in Toxicology, Journal Year: 2025, Volume and Issue: 7

Published: Feb. 26, 2025

Poisoning is a global public health problem that has more unfavorable outcomes in developing countries. This study aimed to assess treatment and associated factors among poisoned patients treated at Saint Peter Specialized Hospital Toxicology Center. An institutional-based retrospective cohort was employed by reviewing medical chart records of acutely who had been admitted St. Center on 01/01/2017 30/12/2023 the review from 01/01/2024 30/01/2024. analyzed 553 patients. A systematic random sampling technique used select unit. Data were entered using Statistical Package for Social Sciences (SPSS) Windows version 26. binary logistic regression model identify p-value <0.05 considered statistically significant. total documents assessed. The overall mortality rate 18 (3.25%), four developed chronic complications. Factor analyses show arrival center before 4 h (AOR = 0.43, P 0.008) predicted recovery, whereas toxicology after 8 2.21, 0.004), being hypotensive 1.85, 0.002), needing intubation 2.52, 0.014), presence two or complication 3.3, < 0.001) admission predictors mortality. (3.25%). In this study, delayed center, hypotensive, intubation, complications with morbidity Establishing strong referral link between regional institutions, ensuring availability possible advanced clinical setup early recognition, aggressively resuscitating critically ill will help minimize outcomes.

Language: Английский

The performance of ejection fraction as a predictor of mortality and morbidity in acute aluminium phosphide poisoning

Toxicology Research, Journal Year: 2024, Volume and Issue: 14(1)

Published: Dec. 27, 2024

Aluminium phosphide poison become an alarming, well-known, effective suicidal with a high mortality rate. There is need for simple tool that can triage patients bad prognosis. The study aimed to assess the accuracy of ejection fraction as predictor and morbidity in acute aluminium toxicity cases. involved 70 cases acutely phosphide-poisoned our hospital from January 2021 2024. found 54.3% were males 45.7% females, mean age 22.4 ± 11.8 years old. oral route was administration all cases, intention poisoning intentional 84.3% Regarding outcome patients, 62.9% recovered, 37.1% died. Receiver Operating Characteristic Curve below 37.5% had rate 96.8% excellent discrimination mortality, sensitivity 100%, specificity 93.2%, positive predictive value 89.6%, negative 100%. 52.5% 89% good complications, 83.3%, 96.8%, 90.9%, 93.7%. So, plays essential predicting complications should be assessed on every patient first 24 h admission facilitate these patients.

Language: Английский