A Review on Biosensors for Quantification of MCP‐1 as a Potential Biomarker in Diseases DOI

Zahra Jamalizadeh Bahaabadi,

Mohammad Javad Javid‐Naderi,

Prashant Kesharwani

et al.

Immunology, Journal Year: 2025, Volume and Issue: unknown

Published: May 14, 2025

ABSTRACT Monocyte chemoattractant protein‐1 (MCP‐1) as a chemokine is essential for inflammation‐related processes. It regulates immunological responses and cell migration, which contribute to inflammation. Many disorders are exacerbated by this chemokine, attracts or grows other inflammatory cells, including monocytes/macrophages, at the site of infection tissue injury. The elevated concentrations MCP‐1 associated with pathogenesis many diseases, such cancer, cardiovascular disease, kidney neuroinflammatory disease. Therefore, monitoring biomarker in body has been recommended strongly advised make an accurate diagnosis prognosis. Although great importance disease processes, few biosensing approaches specifically designed detect molecule. These often electrochemical optical techniques. Rapid diseases identifying biomarkers had effect on advancement biosensors. Improved biosensor technology expansion prevents excessive prices low sensitivity, enabling quick correct tracking This review will concentrate biological functions MCP‐1, its significance different disorders, features applications biosensors detection quantification.

Language: Английский

Deep learning techniques for detection and prediction of pandemic diseases: a systematic literature review DOI Creative Commons
Sunday Adeola Ajagbe, Matthew O. Adigun

Multimedia Tools and Applications, Journal Year: 2023, Volume and Issue: 83(2), P. 5893 - 5927

Published: May 29, 2023

Abstract Deep learning (DL) is becoming a fast-growing field in the medical domain and it helps timely detection of any infectious disease (IDs) essential to management diseases prediction future occurrences. Many scientists scholars have implemented DL techniques for pandemics, IDs other healthcare-related purposes, these outcomes are with various limitations research gaps. For purpose achieving an accurate, efficient less complicated DL-based system therefore, this study carried out systematic literature review (SLR) on pandemics using techniques. The survey anchored by four objectives state-of-the-art forty-five papers seven hundred ninety retrieved from different scholarly databases was analyze evaluate trend application areas pandemics. This used tables graphs extracted related articles online repositories analysis showed that good tool pandemic prediction. Scopus Web Science given attention current because they contain suitable scientific findings subject area. Finally, presents forty-four (44) studies technique performances. challenges identified include low performance model due computational complexities, improper labeling absence high-quality dataset among others. suggests possible solutions such as development improved or reduction output layer architecture pandemic-prone considerations.

Language: Английский

Citations

79

Opportunities and limits of wastewater-based epidemiology for tracking global health and attainment of UN sustainable development goals DOI Creative Commons
Sangeet Adhikari, Rolf U. Halden

Environment International, Journal Year: 2022, Volume and Issue: 163, P. 107217 - 107217

Published: March 27, 2022

Wastewater-based epidemiology (WBE) emerged as a powerful, actionable health management tool during the COVID-19 pandemic. Hypothesizing future uses, we explored its potential for real-time, tracking of progress in attaining United Nations Sustainable Development Goals (SDGs) globally non-expensive method using existing infrastructure. We inventoried (i) literature-documented sewerage infrastructure, (ii) demographics populations served, and (iii) WBE markers informative 9 SDGs. Among 17 different sustainable development goals listed by UN 2030 agenda, more than half these may be monitored monitoring at centralized treatment infrastructure tabulated this study. Driven mainly COVID-19, currently is practiced least 55 countries, reaching about 300 million people. Expansion to 109,000 + plants 129 countries would increase global coverage 9-fold 34.7% or 2.7 billion, leaving out 5 billion people not served systems. Associations between population present-day are explored, geospatial regions particularly vulnerable infectious disease outbreaks identified. The results suggest that difference differential outcomes well-being an outcome sanitation inequalities lack creates doubly disadvantaged risk poor hygiene cut off from early-warning benefits conventional WBE. This first study explore feasibility barriers use attainment SDGs with

Language: Английский

Citations

77

Nanofarming: Promising Solutions for the Future of the Global Agricultural Industry DOI Creative Commons
Hassan El-Ramady, Neama Abdalla,

Daniella Sári

et al.

Agronomy, Journal Year: 2023, Volume and Issue: 13(6), P. 1600 - 1600

Published: June 13, 2023

The agricultural sector is a vital source of human well-being that provides the necessities daily life. A variety farming systems are utilized in agriculture, such as wide range tillage options, no-till, agroforestry, precision farming, organic cover cropping, crop rotations, etc. Each these has unique challenges, and nanotechnology successfully improved on many them. Agricultural applications include nanofertilizers, nanopesticides, nanosensors, nanobiotechnology, nanoremediation. This study focuses application nano-farming technologies to different systems. Suggested practices nano improvement soil quality, nano-protection under biotic stress, nanoremediation polluted water environments, nanomanagement agro-wastes, nano-agrochemicals, nano-precision nanobiotechnology for modern farming. review also addresses expected problems may occur due over nanomaterials systems, nanopollution nanotoxicity agroecosystem compartments. Several dimensions emphasized this study, green energy, sustainable development, circular bioeconomy, land biodegradation, pollution, one health approach, essential global goals development. Nanofarming presents both benefits obstacles exact balance between challenges needs more study.

Language: Английский

Citations

45

Microplastics and other emerging contaminants in the environment after COVID-19 pandemic: The need of global reconnaissance studies DOI Open Access
Yolanda Picó, ‪Damià Barceló

Current Opinion in Environmental Science & Health, Journal Year: 2023, Volume and Issue: 33, P. 100468 - 100468

Published: April 11, 2023

Language: Английский

Citations

33

Emerging technologies revolutionising disease diagnosis and monitoring in aquatic animal health DOI Creative Commons
Kailash Bohara, Pabitra Joshi, Krishna Prasad Acharya

et al.

Reviews in Aquaculture, Journal Year: 2023, Volume and Issue: 16(2), P. 836 - 854

Published: Oct. 30, 2023

Abstract In recent years, aquaculture has seen tremendous growth worldwide due to technological advancements, leading research and development of various innovations. Aquaculture farmers prioritise early diagnosis for timely treatment achieve better productive economic performance. Aquatic animal health experts still employ traditional diagnostic methods using visual diagnosis, cell culture, media histopathology serology. However, the developments technologies in aquamedicine, such as sequencing, biosensors CRISPR, have enabled rapid disease detection within minutes. Furthermore, integrating sensors, drones, artificial intelligence internet farm monitoring helped take decisive actions improve production. Advancements techniques significantly enhanced efficient bacterial, viral, parasitic fungal diseases aquatic animals. Moreover, water quality, behaviour on farms become exceptionally streamlined with cutting‐edge tools like sensors intelligence. Summarising aids technology adoption aquaculture. With these advanced technologies' continued developed countries, industry is experiencing increased efficiency, benefiting consumers regions. educators developing countries lack information about technologies. Training agricultural dissemination knowledge through advertising publication collaboration companies essential. This review delves into emerging capable replacing conventional utilised We also explore their strengths, limitations potential future applications settings.

Language: Английский

Citations

31

Wastewater surveillance for viral pathogens: A tool for public health DOI Creative Commons
Matheus Carmo dos Santos,

Ana Clara Cerqueira Silva,

Carine dos Reis Teixeira

et al.

Heliyon, Journal Year: 2024, Volume and Issue: 10(13), P. e33873 - e33873

Published: June 29, 2024

A focus on water quality has intensified globally, considering its critical role in sustaining life and ecosystems. Wastewater, reflecting societal development, profoundly impacts public health. Wastewater-based epidemiology (WBE) emerged as a surveillance tool for detecting outbreaks early, monitoring infectious disease trends, providing real-time insights, particularly vulnerable communities. WBE aids tracking pathogens, including viruses, sewage, offering comprehensive understanding of community health lifestyle habits. With the rise global COVID-19 cases, gained prominence, aiding SARS-CoV-2 levels worldwide. Despite advancements treatment, poorly treated wastewater discharge remains threat, amplifying spread water-, sanitation-, hygiene (WaSH)-related diseases. WBE, serving complementary surveillance, is pivotal community-level viral infections. However, there untapped potential to expand surveillance. This review emphasizes importance link between health, highlighting need further integration into management.

Language: Английский

Citations

14

Integration of microfluidic chips with biosensors DOI Creative Commons

Masindi Sekhwama,

Kelvin Mpofu,

Sivarasu Sudesh

et al.

Deleted Journal, Journal Year: 2024, Volume and Issue: 6(9)

Published: Aug. 23, 2024

Abstract The potential threat posed by disease outbreaks to diagnostic instruments demands the development of more effective biosensor technologies counteract risks. Diseases like SARS-CoV-2, Ebola, malaria, cholera, and many have demonstrated beyond limits health care that new advancements are required for early detection diagnosis. rising number diseases has led an increasing demand biosensors quicker utilize in healthcare settings. A incorporated with microfluidic chips offers improved compared traditional or classical biosensors. Microfluidic improve performance allowing automation, mixing, separation, throughput processing, transport analytes desired reactors. a chip sensitivity, easy operation can use small volumes samples process results. effectiveness depends also on materials used its fabrication there which reviewed this work. This paper reviews advantages enhance biosensors, fabricate chips, electrodes into time shortening processing at point service. work not previously addressed other including, integration cell-imprinted polymers sensors delved future outlook.

Language: Английский

Citations

12

Optical biosensors for the detection of foodborne pathogens: recent development and future prospects DOI
Yuhe Wang,

Kaiyuan Jia,

Jianhan Lin

et al.

TrAC Trends in Analytical Chemistry, Journal Year: 2024, Volume and Issue: 177, P. 117785 - 117785

Published: May 22, 2024

Language: Английский

Citations

11

A review of wastewater-based epidemiology for antimicrobial resistance surveillance DOI Open Access

Leah Clarke,

Jake O’Brien, Aimee K. Murray

et al.

Journal of Environmental Exposure Assessment, Journal Year: 2024, Volume and Issue: 3(1)

Published: Feb. 26, 2024

Antimicrobial resistance (AMR) is recognized as one of the most serious threats to public health. Unparalleled population growth and accelerated rates AMR emergence dissemination have resulted in both novel pathogenic organisms re-appearance infections that were formerly under control. Consequently, this has led an increased quantity infectious diseases. One main drivers antimicrobial overuse inappropriate prescribing human veterinary medicine. The ability rapidly survey spread within populations key for its prevention, intervention, However, many constraints are present current clinical surveillance systems their capacity determine dynamics microbiome healthy individuals well pathogens causing infections. Wastewater-based epidemiology (WBE) emergent technique act a supplementary measure disease early warning system outbreaks. development outbreaks community level can be monitored real time through analysis pooled wastewater. This review provides introduction using wastewater-based monitor bacteria, overview components.

Language: Английский

Citations

10

Recent Advances in Biosensor Technologies for Meat Production Chain DOI Creative Commons
Ivan Nastasijević, Ivana Kundačina, Stefan Jarić

et al.

Foods, Journal Year: 2025, Volume and Issue: 14(5), P. 744 - 744

Published: Feb. 22, 2025

Biosensors are innovative and cost-effective analytical devices that integrate biological recognition elements (bioreceptors) with transducers to detect specific substances (biomolecules), providing a high sensitivity specificity for the rapid accurate point-of-care (POC) quantitative detection of selected biomolecules. In meat production chain, their application has gained attention due increasing demand enhanced food safety, quality assurance, fraud detection, regulatory compliance. can foodborne pathogens (Salmonella, Campylobacter, Shiga-toxin-producing E. coli/STEC, L. monocytogenes, etc.), spoilage bacteria indicators, contaminants (pesticides, dioxins, mycotoxins), antibiotics, antimicrobial resistance genes, hormones (growth promoters stress hormones), metabolites (acute-phase proteins as inflammation markers) at different modules along from livestock farming packaging in farm-to-fork (F2F) continuum. By real-time data biosensors enable early interventions, reducing health risks (foodborne outbreaks) associated contaminated meat/meat products or sub-standard products. Recent advancements micro- nanotechnology, microfluidics, wireless communication have further sensitivity, specificity, portability, automation biosensors, making them suitable on-site field applications. The integration blockchain Internet Things (IoT) systems allows acquired management, while artificial intelligence (AI) machine learning (ML) enables processing, analytics, input risk assessment by competent authorities. This promotes transparency traceability within fostering consumer trust industry accountability. Despite biosensors' promising potential, challenges such scalability, reliability complexity matrices, approval still main challenges. review provides broad overview most relevant aspects current state-of-the-art development, challenges, opportunities prospective applications regular use safety monitoring, clarifying perspectives.

Language: Английский

Citations

2