Acoustofluidic Actuation of Living Cells DOI Creative Commons
Yue Wu,

Junyang Gai,

Yuwen Zhao

et al.

Micromachines, Journal Year: 2024, Volume and Issue: 15(4), P. 466 - 466

Published: March 29, 2024

Acoutofluidics is an increasingly developing and maturing technical discipline. With the advantages of being label-free, non-contact, bio-friendly, high-resolution, remote-controllable, it very suitable for operation living cells. After decades fundamental laboratory research, its principles have become clear, manufacturing technology has gradually popularized. Presently, various imaginative applications continue to emerge are constantly improved. Here, we introduce development acoustofluidic actuation from perspective related manipulation on Among them, focus main directions such as sorting, tissue engineering, microscopy, biophysical therapy. This review aims provide a concise summary current state research bridge past developments with future directions, offering researchers comprehensive overview sparking innovation in field.

Language: Английский

A high-power ultrasonic transducer operated in MHz range by circular plate bending mode using a single parabolic reflector DOI Creative Commons
W. B. Wang, Kyohei Yamada, Hiroshi Hasegawa

et al.

Japanese Journal of Applied Physics, Journal Year: 2024, Volume and Issue: 63(4), P. 04SP27 - 04SP27

Published: March 6, 2024

Abstract This research developed a HF, high-power ultrasonic transducer. Operating at 1.54 MHz, the transducer generated plane waves through excitation of thickness mode piezoelectric ring. These are subsequently focused by parabolic reflector, exciting bending circular plate and yielding substantial mechanical output center. Under driving voltage 48 V pp , achieved saturation velocity 11.7 m /s. The quality factor ( Q m ) resonant is calculated using half-power bandwidth method, resulting in value approximately 1250. proposed exhibits outstanding performance holds promising applications fields biology, medicine, sonochemistry.

Language: Английский

Citations

2

High-speed and acceleration micrometric jets induced by GHz streaming: A numerical study with direct numerical simulations DOI
Virginie Daru, Bjarne Vincent, Michaël Baudoin

et al.

The Journal of the Acoustical Society of America, Journal Year: 2024, Volume and Issue: 155(4), P. 2470 - 2481

Published: April 1, 2024

Gigahertz acoustic streaming enables the synthesis of localized microjets reaching speeds up to meters per second, offering tremendous potential for precision micromanipulation. However, theoretical and numerical investigations at these frequencies remain so far relatively scarce due significant challenges including: (i) inappropriateness classical approaches, rooted in asymptotic development, addressing high-speed with flow velocities comparable velocity; (ii) cost direct simulations generally considered as prohibitive. In this paper, we investigate high-frequency bulk using high-order finite difference simulations. First, demonstrate that micrometric jets several second can only be obtained high frequencies, diffraction limits. Second, establish maximum jet speed a given actuation power scales frequency 3/2 low attenuation limit linearly strongly attenuated waves. Last, our analysis transient regimes reveals dramatic reduction time required reach velocity increases (power law -5/2), leading characteristic on order μs gigahertz hence accelerations within Mega-g range.

Language: Английский

Citations

2

Study of micro-scale flow characteristics under surface acoustic waves DOI Open Access
Siyu Zhao, Zhaomiao Liu, Yanlin Ren

et al.

Physics of Fluids, Journal Year: 2023, Volume and Issue: 35(8)

Published: Aug. 1, 2023

As an effective tool for contactless manipulation of submicrometer scale objects, the controllability acoustic streaming velocity and flow field morphology determines accuracy object migration completeness three dimensional (3D) imaging. This paper proposes equivalent driving force model that is applicable to both two (2D) 3D calculations constructs a numerical method microsphere rotation in streaming. The results show relationship between peripheral vortex size Lp/wc relative vas/vf satisfies = 0.125vas/vf0.36 under certain geometrical conditions. Reducing spatial confinement increasing inter-vortex distance will increase energy release efficiency, reduce pressure gradient distribution convective dissipation rates, intensity radiation range, consequently, characteristic size. In complex fields, suspended objects are affected by distributions exhibit motions such as cross-flow lines rotation. For larger structure sizes, full imaging more favorable due increased speed period motion along orbit microspheres. study helps us reveal modulation mechanism characteristics, enrich basic theory alternating orbital forces on structures, provide guidance flow-based manipulation.

Language: Английский

Citations

5

Recent progress on acoustofluidic manipulation of cells and particles DOI Creative Commons
Zeyu Wang, Jianping Xia,

Ryan Garry

et al.

National Science Open, Journal Year: 2024, Volume and Issue: unknown, P. 20230080 - 20230080

Published: March 1, 2024

Acoustofluidics, an interdisciplinary nexus of microfluidics and acoustics, is propelling the critical functionalities manipulation, separation, mixing within microscale environments. This integration leverages accuracy with manipulation capabilities thereby enhancing vital sample processing steps satisfying inquiries in experiments. To fulfill requisites practical application clinical research arenas, evolution acoustofluidics concentrates on accomplishing finer particle instantaneous augmented capacity. Acoustofluidics has evolved into a sophisticated versatile instrument for handling specimens reactants, prompting trend towards devices characterized by stable performance at elevated frequencies, programmable control, seamless auxiliary microfluidic systems. In this review, we present latest advancements development acoustofluidic systems that enhance efficiency enable precise modulation across spatial temporal scales, extending their functionality suitability applications.

Language: Английский

Citations

1

Acoustofluidic Actuation of Living Cells DOI Creative Commons
Yue Wu,

Junyang Gai,

Yuwen Zhao

et al.

Micromachines, Journal Year: 2024, Volume and Issue: 15(4), P. 466 - 466

Published: March 29, 2024

Acoutofluidics is an increasingly developing and maturing technical discipline. With the advantages of being label-free, non-contact, bio-friendly, high-resolution, remote-controllable, it very suitable for operation living cells. After decades fundamental laboratory research, its principles have become clear, manufacturing technology has gradually popularized. Presently, various imaginative applications continue to emerge are constantly improved. Here, we introduce development acoustofluidic actuation from perspective related manipulation on Among them, focus main directions such as sorting, tissue engineering, microscopy, biophysical therapy. This review aims provide a concise summary current state research bridge past developments with future directions, offering researchers comprehensive overview sparking innovation in field.

Language: Английский

Citations

1