Many
natural
products
(NPs)
exhibit
strong
antioxidant
activity,
making
them
valuable
for
various
applications.
In
this
context,
the
emergence
of
deep
eutectic
solvents
(DESs)
is
expected
to
help
address
growing
demand
innovative,
efficient,
and
more
sustainable
methods
NPs
extraction.
DESs
are
designer
that
provide
higher
yields
enhance
activity
extracted
phytochemicals
compared
with
conventional
volatile
organic
solvents.
Antioxidant
naturally
occurring
molecules
can
also
form
DESs,
either
as
hydrogen
bond
donors
(HBD)
or
acceptors
(HBA),
creating
DES
(NADES)
inherent
activity.
Thus,
containing
exert
synergistic
effects,
entire
system
a
promising
active
ingredient
food
industry
The
synergy
arises
from
enhanced
solubilization
stabilization
in
through
bonding,
ionic
interactions,
van
der
Waals
forces.
Collectively,
enable
effectively
neutralize
oxidants
(such
ROS
free
radicals)
regulate
their
reactions
other
molecules,
achieving
up
3-fold
increase
extracts
regular
vitro.
This
Account
overviews
wide
range
resources
using
DESs.
activities
HBA,
HBD,
along
advantageous
coupling
extracts,
thoroughly
discussed.
Finally,
we
envisage
future
directions
potential
applications
harnessing
collective
guide
advances
chemistry.
Foods,
Journal Year:
2025,
Volume and Issue:
14(2), P. 291 - 291
Published: Jan. 17, 2025
Centella
asiatica
(CA),
known
for
its
health-promoting
properties,
is
rich
in
bioactive
compounds.
This
study
optimised
ultrasound-assisted
extraction
(UAE)
parameters
to
maximise
total
phenolic
content
(TPC)
and
flavonoid
(TFC)
using
the
response
surface
methodology
(RSM).
Ethanol
concentration
solvent
volume
significantly
influenced
TPC
TFC
yields
(p
<
0.0001),
while
ultrasonic
power
had
nonsignificant
effects
0.05).
Time
showed
no
significant
effect
on
>
0.05)
but
due
flavonoids’
sensitivity
degradation
Variable
interactions
were
negligible
The
relationship
between
responses
(TPC
TFC)
independent
could
be
expressed
as
quadratic
models
fitted
with
a
Predicted
R2
of
0.8263
0.9006
TFC.
Based
RSM,
optimal
conditions—75%
ethanol
concentration,
87.5
W
power,
30
min
time,
20
mL
volume—yielded
values
52.29
±
1.65
mg/g
43.71
1.92
mg/g,
closely
aligning
model
predictions
at
95%
confidence.
Additionally,
UAE
condition
provided
asiaticoside
37.56
4.25
madecassoside
16.91
1.28
mg/g.
offers
valuable
insights
into
factors
influencing
efficiency,
sustainability,
scalability
recovering
compounds,
underscoring
potential
sustainable
method
developing
functional
food
ingredients
from
CA.
Analytical Methods,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Jan. 1, 2025
Analytical
chemistry
demands
precise
sample
preparation
methods
to
ensure
accurate
qualitative
and
quantitative
determinations,
especially
those
capable
of
clean-up
preconcentration
target
analytes.
ABSTRACT
Mushrooms
have
long
been
an
integral
part
of
human
culture
and
health
are
valued
for
their
nutritional
therapeutic
properties.
Often
referred
to
as
a
superfood,
mushrooms
rich
in
bioactive
compounds
that
provide
range
benefits
including
antioxidant,
antimicrobial,
anticancer,
prebiotic,
antidiabetic,
anti‐inflammatory
effects.
This
review
focussed
on
the
diversity
mushrooms,
emphasizing
medicinal
significance,
explores
secondary
metabolites
with
potential
applications
nutraceuticals
pharmaceuticals.
It
underscores
role
vital
agents
developing
value‐added
products.
An
overview
compounds,
such
polysaccharides,
peptides,
proteins,
terpenoids,
phenolic
identified
numerous
mushroom
species.
Additionally,
addresses
advancements
fungal
biotechnology,
particularly
use
fungi
efficient
industrial
cell
factories,
influence
food
quality
sustainability.
By
critically
analyzing
recent
studies,
summarizes
diverse
roles
biomolecules
pharmaceutical
industries
highlights
significant
contribution
modern
medicine
health‐related
fields.
Molecules,
Journal Year:
2024,
Volume and Issue:
29(10), P. 2385 - 2385
Published: May 19, 2024
Natural
deep
eutectic
solvents
(NADESs),
as
emerging
green
solvents,
can
efficiently
extract
natural
products
from
resources.
However,
studies
on
the
extraction
of
phenolic
compounds
celtuce
(Lactuca
sativa
var.
augustana)
leaves
(CLs)
by
NADESs
are
still
lacking.
This
study
screened
NADES
L-proline-lactic
acid
(Pr-LA),
combined
it
with
ultrasound-assisted
(UAE)
to
CLs,
and
conducted
a
comparative
effect
traditional
solvents.
Both
SEM
FT-IR
confirmed
that
Pr-LA
enhance
degree
fragmentation
cell
structures
improve
rate
compounds.
Molecular
dynamics
simulation
results
show
solubility
has
stronger
hydrogen
bonds
van
der
Waals
interactions
Single-factor
Box–Behnken
experiments
optimized
process
parameters
for
CLs.
The
second-order
kinetic
model
describes
CLs
under
optimal
provides
theoretical
guidance
actual
industrial
production.
not
only
an
efficient
method
extracting
but
also
clarifies
mechanism
improved
efficiency,
which
basis
research
mechanism.
Compounds,
Journal Year:
2025,
Volume and Issue:
5(1), P. 2 - 2
Published: Jan. 3, 2025
Plant-derived
secondary
metabolites
such
as
triterpenes
and
triterpenoids
are
present
in
a
wide
range
of
plant
species.
These
compounds
particularly
attractive
due
to
their
extensive
biological
properties
potential
applications
intermediates
the
synthesis
novel
pharmacologically
promising
medications.
Saponins,
which
glycosylated
found
nature,
exhibit
same
properties.
At
this
point,
effectiveness
saponins
an
anti-inflammatory
medication
has
been
verified.
This
review
article
examines
primary
connections
between
immune
responses
activity,
focusing
specifically
on
correlation
triterpenoids.
have
investigated
various
cell
models,
well
vitro
vivo
studies.
The
research
provides
comprehensive
overview
current
understanding
therapeutic
capabilities
inflammatory
processes.
It
also
highlights
emerging
standards
utilization
pharmaceutical
clinical
settings.
Geothermal
reservoir
engineering
is
pivotal
to
sustainable
energy,
focusing
on
optimizing
heat
extraction
for
enhanced
geothermal
production.
This
discipline
integrates
geological
and
geophysical
studies
characterize
reservoirs,
considering
permeability,
porosity,
temperature
distribution.
Enhanced
Systems
(EGS)
improve
subsurface
permeability
exchange
through
hydraulic,
thermal,
chemical
stimulation.
Advanced
numerical
modeling
predicts
behavior,
fluid
flow,
transfer,
sustainability
under
diverse
conditions.
Cutting-edge
techniques
such
as
directional
drilling
downhole
sensors
minimize
environmental
impact
while
providing
real-time
data
effective
management.
Reservoir
optimization
combines
characterization,
modeling,
innovative
technologies.
Insights
from
global
projects
demonstrate
how
optimized
strategies
boost
energy
output
sustainability.
These
advancements
highlight
engineering's
role
in
meeting
demands
with
minimal
impact,
ensuring
a
cleaner,
greener
future.
