Ultrasensitive Sulphide Detecting by Using Au (core)-Ag (shell) Triangular Nanoprisms DOI Creative Commons

Shihao Feng,

Zhixiang Liu, Mei Liu

et al.

Optics Express, Journal Year: 2024, Volume and Issue: 32(27), P. 49082 - 49082

Published: Dec. 12, 2024

Hydrogen sulfide (H 2 S), the third endogenous gaseous molecule, plays a crucial role in biological signaling and metabolic processes. It has garnered significant attention from researchers field of biochemistry. The highly sensitive detection H S is essential for elucidating its functions long been key objective biochemical sensing. In this study, we present an ultrasensitive method utilizing gold (core)-silver (shell) triangular nanoprisms (Au@Ag TNPs). This strategy predicated on preferential formation Ag at sharp corners Au@Ag TNPs, which manifested as spectral shift observed nanoprobes. comparison to limit using nanorods, reported Nat. Commun. 4 , 1708 ( 2013 ) 10.1038/ncomms2722 can be enhanced by three orders magnitude when employing TNPs. Leveraging single-particle scattering spectrum individual have successfully reduced 1 fM. represents lowest value date. study presents effective plasmonic nanoprobe detection, poised play biochemistry environmental sciences.

Language: Английский

Plasmonic Biosensors for Health Monitoring: Inflammation Biomarker Detection DOI
Muhammad Amirul Islam, Jean‐François Masson

ACS Sensors, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 7, 2025

Surface plasmon resonance (SPR) and localized SPR (LSPR) biosensors have emerged as viable technologies in the clinical detection of biomarkers for a wide array health conditions. The success lies their ability to monitor real-time label-free complex biofluids. Recent breakthroughs nanotechnology surface chemistry significantly improved this feature, notably from incorporation advanced nanomaterials including gold nanoparticles, graphene, carbon nanotubes providing better sensor performance terms limits, stability, specificity. progress microfluidic integration has enabled detect multiple simultaneously biological samples. Taken together, these advances are closing gap use diagnostics point-of-care (POC) applications. While broadly applicable, latest advancements plasmonic biosensing overviewed using inflammation C-reactive protein (CRP), interleukins (ILs), tumor necrosis factor-α (TNF-α), procalcitonin (PCT), ferritin, fibrinogen series conditions, cardiovascular diseases, autoimmune disorders, infections, sepsis, key example We highlight developments design, nanomaterial integration, functionalization, multiplexing provide look forward applications by assessing current limitations exploring future directions translating monitoring. By enhancement diagnostic accuracy, reproducibility, accessibility, particularly POC settings, potential contribute personalized healthcare bring real-time, high-precision forefront practice.

Language: Английский

Citations

1
Tunable localized surface plasmon resonance absorption in silver-based nanoplasmonics DOI
Biljana Pejova,

Emel Sherif Miftar

Journal of Materials Science Materials in Electronics, Journal Year: 2025, Volume and Issue: 36(2)

Published: Jan. 1, 2025

Language: Английский

Citations

0
Three-Dimensional Polyglycerol–PEG-Based Hydrogels as a Universal High-Sensitivity Platform for SPR Analysis DOI Creative Commons

Clemens Krage,

Seyma Adigüzel,

Boonya Thongrom

et al.

Analytical Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: March 13, 2025

We developed a three-dimensional (3D) polyglycerol–poly(ethylene glycol)-based hydrogel as new biosensing matrix for affinity analysis by surface plasmon resonance to enable high loading of ligands small molecule while lacking carbohydrate structure reduce nonspecific binding. The was synthesized cross-linking polyglycerol functionalized with carboxylate and maleimide groups dithiolated poly(ethylene glycol) thiol-click chemistry. demonstrated that the coating enabled immobilization capacity biomolecules led less Here, degree carbonic anhydrase II resulting binding signal acetazolamide were increased factor 5 compared standard CMD sensors (CM5), comparable specialized maximum (CM7). This capacity, combined reduced due missing structure, presents an innovative broad application range (SPR) experiments since no current commercial SPR biosensor combines these two key features.

Language: Английский

Citations

0
Promising Solutions to Address the Non-Specific Adsorption in Biosensors Based on Coupled Electrochemical-Surface Plasmon Resonance Detection DOI Creative Commons
Alina Vasilescu, Szilveszter Gáspár, Mihaela Gheorghiu

et al.

Chemosensors, Journal Year: 2025, Volume and Issue: 13(3), P. 92 - 92

Published: March 5, 2025

Nonspecific adsorption (NSA) impacts the performance of biosensors in complex samples. Coupled electrochemical–surface plasmon resonance (EC-SPR) offer interesting opportunities to evaluate NSA. This review details main solutions minimize fouling electrochemical (EC), surface (SPR) and EC-SPR biosensors. The discussion was centered on blood, serum milk as examples matrices. Emphasis placed antifouling coatings, NSA evaluation protocols universal functionalization strategies obtain In last 5 years, various coatings were developed for EC biosensors, including new peptides, cross-linked protein films hybrid materials. Due comparatively much more scarce literature, SPR extended early 2010s. analysis revealed a wide range materials with tunable conductivity, thickness functional groups that can be tested future EC-SPR. high-throughput screening materials, molecular simulations machine learning-assisted evaluations will even further widen available minimization NSA’s impact analytical signal is moreover facilitated by unique sensing mechanisms associated bioreceptor or particularities detection method. It hoped this encourage research field

Language: Английский

Citations

0
Ultrasensitive Sulphide Detecting by Using Au (core)-Ag (shell) Triangular Nanoprisms DOI Creative Commons

Shihao Feng,

Zhixiang Liu, Mei Liu

et al.

Optics Express, Journal Year: 2024, Volume and Issue: 32(27), P. 49082 - 49082

Published: Dec. 12, 2024

Hydrogen sulfide (H 2 S), the third endogenous gaseous molecule, plays a crucial role in biological signaling and metabolic processes. It has garnered significant attention from researchers field of biochemistry. The highly sensitive detection H S is essential for elucidating its functions long been key objective biochemical sensing. In this study, we present an ultrasensitive method utilizing gold (core)-silver (shell) triangular nanoprisms (Au@Ag TNPs). This strategy predicated on preferential formation Ag at sharp corners Au@Ag TNPs, which manifested as spectral shift observed nanoprobes. comparison to limit using nanorods, reported Nat. Commun. 4 , 1708 ( 2013 ) 10.1038/ncomms2722 can be enhanced by three orders magnitude when employing TNPs. Leveraging single-particle scattering spectrum individual have successfully reduced 1 fM. represents lowest value date. study presents effective plasmonic nanoprobe detection, poised play biochemistry environmental sciences.

Language: Английский

Citations

0