Electrochemical sensors for the detection of immune checkpoint related proteins and their role in cancer companion diagnostics DOI Creative Commons

Louise Barnaby,

Andrew G. Watts, Pedro Estrela

et al.

Biosensors and Bioelectronics X, Journal Year: 2024, Volume and Issue: unknown, P. 100561 - 100561

Published: Nov. 1, 2024

Language: Английский

CRISPR integrated biosensors: A new paradigm for cancer detection DOI

Ashok Saini,

Neeraj Dilbaghi, Neelam Yadav

et al.

Clinica Chimica Acta, Journal Year: 2025, Volume and Issue: 569, P. 120179 - 120179

Published: Feb. 1, 2025

Language: Английский

Citations

1
Recent Advances in SAW Sensors for Detection of Cancer Biomarkers DOI Creative Commons
M. Aleixandre, M.C. Horrillo

Biosensors, Journal Year: 2025, Volume and Issue: 15(2), P. 88 - 88

Published: Feb. 5, 2025

Surface acoustic wave (SAW) sensor technology is a promising approach to diagnosing cancer through the detection of biomarkers due its high sensitivity, potential label-free operation, and fast response times, and, fundamentally, because it non-invasive technique in comparison with current traditional diagnostic techniques for cancer. This review focuses on this application, purpose, recent literature detected by advanced has been compiled, including that volatile organic compounds (VOCs) from exhaled breath larger biomolecules such as proteins, DNA, microRNAs body fluids, which demonstrates great versatility. The conventional biomarker biofluids, ELISA, PCR, SPR, UV absorbance, exhibit limitations costs, slow reduced need specialized instrumentation, requirement highly trained personnel. Different SAW configurations are discussed attention paid their specific properties, propagation modes, suitability different environments. Detailed studies reviewed, highlighting lung, colorectal, prostate, breast, ovarian diagnostics, well circulating tumor cells cancerous cell growth. identifies challenges, optimizing addressing environmental interferences, clinical validation. Finally, future research directions proposed, emphasizing use VOC integration into hybrid systems microfluidic platforms enable creation scalable, tools early stages, way, minimize morbidity mortality associated disease.

Language: Английский

Citations

0
Simple graphite/PVC ink-designed paper-based electrodes integrated with a 3D-printed electrochemical device for affordable analyses DOI

Gleidson Thiago Sá Araújo,

Lucas Costa Faustino, Ricardo Marques e Silva

et al.

Microchimica Acta, Journal Year: 2025, Volume and Issue: 192(3)

Published: Feb. 26, 2025

Language: Английский

Citations

0
Development of CdS/ZnS Core–Shell Quantum Dot-based MicroPADs for Sensing Applications DOI
Sourav Sarkar, Manashjit Gogoi, Sanjukta Patra

et al.

Plasmonics, Journal Year: 2025, Volume and Issue: unknown

Published: March 31, 2025

Language: Английский

Citations

0
A Novel Framework for Human Chronic Disease Prediction Using CNN and Adaptive Dragon Fly Optimization (ADFO) Algorithm DOI

B. Ragu,

S. Maruthu Perumal

SN Computer Science, Journal Year: 2025, Volume and Issue: 6(4)

Published: April 3, 2025

Language: Английский

Citations

0
Engineered Intelligent Electrochemical Biosensors for Portable Point-of-Care Diagnostics DOI Creative Commons

Jiamin Lin,

Yuanyuan Chen, Xiaohui Liu

et al.

Chemosensors, Journal Year: 2025, Volume and Issue: 13(4), P. 146 - 146

Published: April 16, 2025

The development of cost-effective, rapid-response, and user-friendly biosensing platforms has become paramount importance for achieving precise biomarker quantification in early disease detection. Implementing timely diagnostic interventions through accurate analysis not only significantly improves treatment outcomes but also enables effective management strategies, ultimately leading to substantial reductions patient mortality rates. These clinical imperatives have consequently driven the innovation portable point-of-care (POC) systems. Electrochemical biosensors are attractive diagnosis diseases due their low cost, simple operation, high sensitivity. This review examines prevalent material innovations electrode functionalization electrochemical platforms, with specific emphasis on translational applications early-stage included three important types: proteins, nucleic acids, small molecule metabolites. Furthermore, work proposes novel research trajectories next-generation biosensor development, advocating synergistic integration artificial intelligence-driven analytics, Internet Medical Things (IoMT)-enabled networks, advanced micro/nanofabrication techniques.

Language: Английский

Citations

0
One-pot target-triggered catalytic DNA assembly for PEC nucleic acid assay based on GDY/CuSe modified electrode DOI
Shenghao Zhang, Meiling Zhang,

Yinhao Zhang

et al.

Microchemical Journal, Journal Year: 2025, Volume and Issue: unknown, P. 113676 - 113676

Published: April 1, 2025

Language: Английский

Citations

0
Copper Vacancy-Doped Cu2-xSe Activating Nanozyme Sensor Arrays for Multiprotein Discrimination and Cancer Screening DOI

Guojuan Yan,

Meng Guo, Ronghua Yang

et al.

Analytical Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: April 23, 2025

Given the complexity and interrelated nature of biological activities, acquiring multitarget information is crucial for accurate cancer diagnosis. In this study, we developed a cross-reactive sensor array using peroxidase-like nonstoichiometric copper selenide nanoparticles (Cu2-xSe), which featured varying vacancies, multiplex protein detection screening. The Cu2-xSe demonstrated outstanding activity that can be modulated to degrees in presence multiple proteins with isoelectric points compositions, generating fingerprint outputs. By integrating pattern recognition method principal component analysis linear discriminant (PCA-LDA), effectively discriminated among six was further applied cells clinical samples, attaining 100% accuracy differentiating patients from healthy individuals, as well identifying specific types, namely, liver prostate cancers. Moreover, proof-of-concept, partial least-squares regression (PLSR) approached AFP PSA within range 0.1-2.0 μg/L complex matrix. These results highlighted practical potential sensing diagnosis by nanozyme-based chemical nose strategies.

Language: Английский

Citations

0
Mof-derived electrochemical immunosensors for cancer biomarker Detection: A Cutting-Edge approach for early diagnosis and biomedical applications DOI
Chou‐Yi Hsu, Ashok Kumar Bishoyi,

Darko A. Noori

et al.

Microchemical Journal, Journal Year: 2025, Volume and Issue: unknown, P. 113860 - 113860

Published: May 1, 2025

Language: Английский

Citations

0
Electrochemical sensors for the detection of immune checkpoint related proteins and their role in cancer companion diagnostics DOI Creative Commons

Louise Barnaby,

Andrew G. Watts, Pedro Estrela

et al.

Biosensors and Bioelectronics X, Journal Year: 2024, Volume and Issue: unknown, P. 100561 - 100561

Published: Nov. 1, 2024

Language: Английский

Citations

0