PHANTOM MODELLING IN MAGNETIC RESONANCE IMAGING: AN OVERVIEW OF MATERIALS FOR SIMULATING TISSUE RELAXATION TIME (REVIEW) DOI Open Access

Yu.A. Vasilev,

Marina Valeryevna Cherkasskaya, Е. С. Ахмад

et al.

Polymer materials and technologies, Journal Year: 2023, Volume and Issue: 9(4), P. 6 - 20

Published: Jan. 1, 2023

Anthropomorphic phantoms are required to mimic the properties, geometry, or functions of human body tissues.Materials used for such models should realistically reproduce certain physical characteristics tissues.The literature lacks comprehensive information on classes compounds that can model biological tissue realistic imaging in magnetic resonance scanning.The purpose this work is search and analyze existing materials simulating t he times spin-lattice (T1) spin-spin (T2) relaxation create MRI phantoms.The article considers methods making compositions tissues.Formulations obtained from aqueous suspensions, hydroge ls presented, as well examples realisation 3D-printing.Hydrogel have been shown be capable accurately reproducing properties various tissues within time range 65 1663 ms.Phantoms made agarose lower production costs, their life extended with introduction special additives.It has noted a modifier T2 time, even other types gelling agen ts.3D-printing technology significantly speeds up phantom modeling process allows you efficiently design complex geometric figures both common affordable (polylactic acid, polymethylmethacrylate, acrylonitrile butadiene styrene) specially developed multicomponent compositions.Based data studied, authors selected control parameters quantitative MRI, also tested it.Further systematization inform ation equivalent will optimize manufacture specific technical clinical tasks.

Language: Английский

Estimation of the Proton Resonance Frequency Coefficient in Agar-based Phantoms DOI Creative Commons
Antria Filippou, Nikolas Evripidou, Andreas Georgiou

et al.

Journal of Medical Physics, Journal Year: 2024, Volume and Issue: 49(2), P. 167 - 180

Published: April 1, 2024

Aim: Agar-based phantoms are popular in high intensity focused ultrasound (HIFU) studies, with magnetic resonance imaging (MRI) preferred for guidance since it provides temperature monitoring by proton frequency (PRF) shift (MR) thermometry. MR thermometry depends on several factors, thus, herein, the PRF coefficient of agar was estimated. Materials and Methods: Seven were developed varied (2, 4, or 6% w/v) constant (6% silica concentrations 6, 8% to assess effect concentration coefficient. Each phantom sonicated using acoustical power a 30 s duration both laboratory setting inside 3T MRI scanner. coefficients estimated through linear trends between phase acquired gradient sequences thermocouple-based temperatures changes. Results: Linear regression ( R 2 = 0.9707–0.9991) demonstrated proportional dependency change, resulting −0.00336 ± 0.00029 −0.00934 0.00050 ppm/°C various recipes. Weak negative correlations observed increased agar. With concentrations, correlation strong. For all phantoms, calibrated resulted 1.01–3.01-fold higher changes compared values calculated literature Conclusions: Phantoms w/v doped 0%–8% best resemble tissue should be HIFU studies. The can result enhanced evaluation protocols.

Language: Английский

Citations

0

Magnetic Resonance Thermometry of Focused Ultrasound Using a Preclinical Focused Ultrasound Robotic System at 3T DOI Creative Commons
Antria Filippou, Nikolas Evripidou, Andreas Georgiou

et al.

Journal of Medical Physics, Journal Year: 2024, Volume and Issue: 49(4), P. 583 - 596

Published: Oct. 1, 2024

Focused ultrasound (FUS) therapies are often performed within magnetic resonance imaging (MRI) systems providing thermometry-based temperature monitoring. Herein, MRI thermometry was assessed for FUS sonications executed using a preclinical system on agar-based phantoms at 1.5T and 3T scanners, the proton frequency shift technique. Sonications were to assess observe variations in (MR) measurements. MR 3T, identical three doped with varied silica evaporated milk concentrations, acoustic power of 1.5-45 W. Moreover, echo time (TE) values 5-20 ms used effect signal-to-noise ratio (SNR) change sensitivity. Clearer thermal maps 2.5-fold higher temporal resolution produced compared 1.5T, despite employment similar sequences. At changes between 41°C 50°C recorded milk, addition 2% w/v resulting 20% increase change. The lowest that reliable beam detection voxel 1.5 A TE 10 resulted highest sensitivity adequate SNR. achieved short dependencies exhibited sonication parameters. Present data could be MRI-guided feasibility studies enhance thermometry.

Language: Английский

Citations

0

Simple, inexpensive, and ergonomic phantom for quality assurance control of MRI guided Focused Ultrasound systems DOI
Anastasia Antoniou, Christakis Damianou

Journal of Ultrasound, Journal Year: 2022, Volume and Issue: 26(2), P. 401 - 408

Published: Nov. 4, 2022

Language: Английский

Citations

1

A Cost-Effective, Agar-based Phantom for Thermogram- Guided Malignancy Analysis DOI

R. Ramyadevi

EAI/Springer Innovations in Communication and Computing, Journal Year: 2023, Volume and Issue: unknown, P. 191 - 199

Published: Jan. 1, 2023

Language: Английский

Citations

0

PHANTOM MODELLING IN MAGNETIC RESONANCE IMAGING: AN OVERVIEW OF MATERIALS FOR SIMULATING TISSUE RELAXATION TIME (REVIEW) DOI Open Access

Yu.A. Vasilev,

Marina Valeryevna Cherkasskaya, Е. С. Ахмад

et al.

Polymer materials and technologies, Journal Year: 2023, Volume and Issue: 9(4), P. 6 - 20

Published: Jan. 1, 2023

Anthropomorphic phantoms are required to mimic the properties, geometry, or functions of human body tissues.Materials used for such models should realistically reproduce certain physical characteristics tissues.The literature lacks comprehensive information on classes compounds that can model biological tissue realistic imaging in magnetic resonance scanning.The purpose this work is search and analyze existing materials simulating t he times spin-lattice (T1) spin-spin (T2) relaxation create MRI phantoms.The article considers methods making compositions tissues.Formulations obtained from aqueous suspensions, hydroge ls presented, as well examples realisation 3D-printing.Hydrogel have been shown be capable accurately reproducing properties various tissues within time range 65 1663 ms.Phantoms made agarose lower production costs, their life extended with introduction special additives.It has noted a modifier T2 time, even other types gelling agen ts.3D-printing technology significantly speeds up phantom modeling process allows you efficiently design complex geometric figures both common affordable (polylactic acid, polymethylmethacrylate, acrylonitrile butadiene styrene) specially developed multicomponent compositions.Based data studied, authors selected control parameters quantitative MRI, also tested it.Further systematization inform ation equivalent will optimize manufacture specific technical clinical tasks.

Language: Английский

Citations

0