Polymer materials and technologies,
Journal Year:
2023,
Volume and Issue:
9(4), P. 6 - 20
Published: Jan. 1, 2023
Anthropomorphic
phantoms
are
required
to
mimic
the
properties,
geometry,
or
functions
of
human
body
tissues.Materials
used
for
such
models
should
realistically
reproduce
certain
physical
characteristics
tissues.The
literature
lacks
comprehensive
information
on
classes
compounds
that
can
model
biological
tissue
realistic
imaging
in
magnetic
resonance
scanning.The
purpose
this
work
is
search
and
analyze
existing
materials
simulating
t
he
times
spin-lattice
(T1)
spin-spin
(T2)
relaxation
create
MRI
phantoms.The
article
considers
methods
making
compositions
tissues.Formulations
obtained
from
aqueous
suspensions,
hydroge
ls
presented,
as
well
examples
realisation
3D-printing.Hydrogel
have
been
shown
be
capable
accurately
reproducing
properties
various
tissues
within
time
range
65
1663
ms.Phantoms
made
agarose
lower
production
costs,
their
life
extended
with
introduction
special
additives.It
has
noted
a
modifier
T2
time,
even
other
types
gelling
agen
ts.3D-printing
technology
significantly
speeds
up
phantom
modeling
process
allows
you
efficiently
design
complex
geometric
figures
both
common
affordable
(polylactic
acid,
polymethylmethacrylate,
acrylonitrile
butadiene
styrene)
specially
developed
multicomponent
compositions.Based
data
studied,
authors
selected
control
parameters
quantitative
MRI,
also
tested
it.Further
systematization
inform
ation
equivalent
will
optimize
manufacture
specific
technical
clinical
tasks.
Journal of Medical Physics,
Journal Year:
2024,
Volume and Issue:
49(2), P. 167 - 180
Published: April 1, 2024
Aim:
Agar-based
phantoms
are
popular
in
high
intensity
focused
ultrasound
(HIFU)
studies,
with
magnetic
resonance
imaging
(MRI)
preferred
for
guidance
since
it
provides
temperature
monitoring
by
proton
frequency
(PRF)
shift
(MR)
thermometry.
MR
thermometry
depends
on
several
factors,
thus,
herein,
the
PRF
coefficient
of
agar
was
estimated.
Materials
and
Methods:
Seven
were
developed
varied
(2,
4,
or
6%
w/v)
constant
(6%
silica
concentrations
6,
8%
to
assess
effect
concentration
coefficient.
Each
phantom
sonicated
using
acoustical
power
a
30
s
duration
both
laboratory
setting
inside
3T
MRI
scanner.
coefficients
estimated
through
linear
trends
between
phase
acquired
gradient
sequences
thermocouple-based
temperatures
changes.
Results:
Linear
regression
(
R
2
=
0.9707–0.9991)
demonstrated
proportional
dependency
change,
resulting
−0.00336
±
0.00029
−0.00934
0.00050
ppm/°C
various
recipes.
Weak
negative
correlations
observed
increased
agar.
With
concentrations,
correlation
strong.
For
all
phantoms,
calibrated
resulted
1.01–3.01-fold
higher
changes
compared
values
calculated
literature
Conclusions:
Phantoms
w/v
doped
0%–8%
best
resemble
tissue
should
be
HIFU
studies.
The
can
result
enhanced
evaluation
protocols.
Journal of Medical Physics,
Journal Year:
2024,
Volume and Issue:
49(4), P. 583 - 596
Published: Oct. 1, 2024
Focused
ultrasound
(FUS)
therapies
are
often
performed
within
magnetic
resonance
imaging
(MRI)
systems
providing
thermometry-based
temperature
monitoring.
Herein,
MRI
thermometry
was
assessed
for
FUS
sonications
executed
using
a
preclinical
system
on
agar-based
phantoms
at
1.5T
and
3T
scanners,
the
proton
frequency
shift
technique.
Sonications
were
to
assess
observe
variations
in
(MR)
measurements.
MR
3T,
identical
three
doped
with
varied
silica
evaporated
milk
concentrations,
acoustic
power
of
1.5-45
W.
Moreover,
echo
time
(TE)
values
5-20
ms
used
effect
signal-to-noise
ratio
(SNR)
change
sensitivity.
Clearer
thermal
maps
2.5-fold
higher
temporal
resolution
produced
compared
1.5T,
despite
employment
similar
sequences.
At
changes
between
41°C
50°C
recorded
milk,
addition
2%
w/v
resulting
20%
increase
change.
The
lowest
that
reliable
beam
detection
voxel
1.5
A
TE
10
resulted
highest
sensitivity
adequate
SNR.
achieved
short
dependencies
exhibited
sonication
parameters.
Present
data
could
be
MRI-guided
feasibility
studies
enhance
thermometry.
Polymer materials and technologies,
Journal Year:
2023,
Volume and Issue:
9(4), P. 6 - 20
Published: Jan. 1, 2023
Anthropomorphic
phantoms
are
required
to
mimic
the
properties,
geometry,
or
functions
of
human
body
tissues.Materials
used
for
such
models
should
realistically
reproduce
certain
physical
characteristics
tissues.The
literature
lacks
comprehensive
information
on
classes
compounds
that
can
model
biological
tissue
realistic
imaging
in
magnetic
resonance
scanning.The
purpose
this
work
is
search
and
analyze
existing
materials
simulating
t
he
times
spin-lattice
(T1)
spin-spin
(T2)
relaxation
create
MRI
phantoms.The
article
considers
methods
making
compositions
tissues.Formulations
obtained
from
aqueous
suspensions,
hydroge
ls
presented,
as
well
examples
realisation
3D-printing.Hydrogel
have
been
shown
be
capable
accurately
reproducing
properties
various
tissues
within
time
range
65
1663
ms.Phantoms
made
agarose
lower
production
costs,
their
life
extended
with
introduction
special
additives.It
has
noted
a
modifier
T2
time,
even
other
types
gelling
agen
ts.3D-printing
technology
significantly
speeds
up
phantom
modeling
process
allows
you
efficiently
design
complex
geometric
figures
both
common
affordable
(polylactic
acid,
polymethylmethacrylate,
acrylonitrile
butadiene
styrene)
specially
developed
multicomponent
compositions.Based
data
studied,
authors
selected
control
parameters
quantitative
MRI,
also
tested
it.Further
systematization
inform
ation
equivalent
will
optimize
manufacture
specific
technical
clinical
tasks.