Multifrequency control of Faraday wave bioassembly for constructing multiscale hPSC-derived neuronal networks DOI Open Access
Longjun Gu, Wen Zhao, Yuhang Fan

et al.

bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2023, Volume and Issue: unknown

Published: Dec. 1, 2023

Abstract Bioassembly is recently regarded as a critical alternative biofabrication technical route to bioprinting since it can directly manipulate millions of live cells form multicellular structures with close intercellular proximity, improving contact-dependent cell communication and promoting the emergence tissue-specific functions. However, acoustic bioassembly techniques are currently limited generating cytoarchitecture single characteristic length which cannot faithfully mimic multiscale cellular in native tissues. To overcome this challenge, herein we report novel technique that employs multifrequency control Faraday waves structures. By superimposing multiple sine wave signals proper amplitude ratios, containing wavelengths be induced enabled generate few seconds. Using technique, construct functional neuronal networks connectivity display spontaneous neuroelectrical activities. We anticipate will find wide applications tissue engineering regenerative medicine.

Language: Английский

Recent advancements in the utilization of ultrasonic technology for the curing of processed meat products: A comprehensive review DOI Creative Commons
Biao Li, Mingming Zhong,

Yufan Sun

et al.

Ultrasonics Sonochemistry, Journal Year: 2024, Volume and Issue: 103, P. 106796 - 106796

Published: Feb. 1, 2024

Curation meat products involves multiple stages, including pre-curing processing (thawing, cleaning, and cutting), curing itself, post-curing (freezing, packaging). Ultrasound are nonthermal technology widely used in food industry. This is preferred because it reduces the damages caused by traditional techniques on food, while simultaneously improving nutritional properties characteristics of food. The utilization ultrasonic-assisted has attracted significant attention within realm product curing, encouraging extensive research efforts. In terms products, been studied due to its advantages accelerating speed, reducing nutrient loss, tenderness cured meats. Therefore, this article aims comprehensively review application mechanism ultrasound various stages curing. Furthermore, also elaborates effects tenderness, water retention, flavor substances during process. Besides, implication curation plays a potent role together with other technologies or methods. use process was analyzed, which might be theoretical insight for industrialization prospects product.

Language: Английский

Citations

15
Acoustic Cell Patterning for Structured Cell‐Laden Hydrogel Fibers/Tubules DOI Creative Commons
Qiu Yin, Yucheng Luo, Xianglin Yu

et al.

Advanced Science, Journal Year: 2024, Volume and Issue: 11(14)

Published: Feb. 2, 2024

Abstract Cell‐laden hydrogel fibers/tubules are one of the fundamentals tissue engineering. They have been proven as a promising method for constructing biomimetic tissues, such muscle fibers, nerve conduits, tendon and vessels, etc. However, current fiber/tubule production methods limitations in ordered cell arrangements, thus impeding configurations. Acoustic patterning is manipulation that has good biocompatibility, wide tunability, contact‐free. there few studies on acoustic fiber production, especially radial figure which mimic many native tissue‐like arrangements. Here, an system can be used to produce with tunable patterns shown. Cells pre‐patterned liquid before being extruded cross‐linked fibers/tubules. The tuned different complexities based resonances. Cell viability assays after 72 h confirm proliferation. Considering biocompatibility reliability, present further variety fabrications.

Language: Английский

Citations

13
Medical Defense Nanorobots (MDNRs): a new evaluation and selection of controller criteria for improved disease diagnosis and patient safety using NARMA(L2)-FOP + D(ANFIS)µ – Iλ-based Archimedes Optimization Algorithm DOI
Hamzah M. Marhoon, Noorulden Basil,

Abdullah Fadhil Mohammed

et al.

International Journal of Information Technology, Journal Year: 2024, Volume and Issue: unknown

Published: Feb. 20, 2024

Language: Английский

Citations

10
Superselective embolic particle guidance in vessel networks via shape-adaptive acoustic manipulation DOI Creative Commons
Yucheng Luo, Qiu Yin, Keke Chen

et al.

Nature Communications, Journal Year: 2025, Volume and Issue: 16(1)

Published: Jan. 2, 2025

Language: Английский

Citations

2
Robotics-assisted modular assembly of bioactive soft materials for enhanced organ fabrication DOI Creative Commons
Dayoon Kang, S. J. Hong, S. J. Kim

et al.

Virtual and Physical Prototyping, Journal Year: 2024, Volume and Issue: 19(1)

Published: Aug. 19, 2024

Tissue engineering, an interdisciplinary field, aims to restore, maintain, or enhance tissue function by developing biological substitutes. To establish optimal microenvironment, biofabrication is acknowledged as a revolutionary technology facilitating the construction of multiscale three-dimensional architectures utilising various living cells and biomaterials. A critical challenge in this domain precise assembly soft matter-delicate pliable structures - essential for creating functional tissues organs. This review focuses on increasing use robotic systems address challenge, exploring their application manipulating matter assembly. Robotic technologies offer innovative solutions handling with precision control. discusses how can be leveraged fabricate complex organs, detailing role replicating structural complexities natural tissues. Further, examining latest advancements robotics-assisted highlights potential robotics revolutionise organ fabrication, offering promising longstanding challenges field. These technological hold capacity engineer presenting considerable translational clinical applications.

Language: Английский

Citations

6
Examining Sound, Light, and Vibrations as Tools to Manage Microbes and Support Holobionts, Ecosystems, and Technologies DOI Creative Commons

Rodney R. Dietert,

Janice M. Dietert

Microorganisms, Journal Year: 2024, Volume and Issue: 12(5), P. 905 - 905

Published: April 30, 2024

The vast array of interconnected microorganisms across Earth's ecosystems and within holobionts has been called the "Internet Microbes." Bacteria archaea are masters energy information collection, storage, transformation, dissemination using both "wired" wireless (at a distance) functions. Specific tools affecting microbial functions offer effective strategies for managing populations within, between, beyond holobionts. This narrative review focuses on management subset physical modifiers microbes: sound light (as well as related vibrations). These examined follows: (1) populations, (2) to support new technologies, (3) healing humans other holobionts, (4) potential safety dangers their Given sensitivity sound, light, vibrations, it is critical that we assign higher priority effects these factors microbe-laden We conclude specific and/or vibrational conditions significant therapeutic can help useful address ongoing challenges holobiont disease. also caution inappropriate vibration exposure represent hazards require greater recognition.

Language: Английский

Citations

3
Principle and experimental study of a combined teardrop and heart-shaped channel bluffbody valveless piezoelectric pump DOI
Dahai Yu, Renhui Hu,

Lintong Han

et al.

Review of Scientific Instruments, Journal Year: 2024, Volume and Issue: 95(6)

Published: June 1, 2024

In this study, we have developed a piezoelectric pump with combined teardrop- and heart-shaped channel based on the Coanda effect bionics principle. The bluffbody consists of channels. vibration flow rate are evaluated theoretically, conditions under different heights main widths simulated. theoretical simulation results show that has uneven resistance to in forward reverse directions, height teardrop width affect channel. Test data same pressure, when is 5 mm 8 mm, 460.8 ml/min. alleviates serious backflow problem through fluid blocking structure expected become an active driver microfluidic devices.

Language: Английский

Citations

3
Reconfigurable Manipulation of Sound with a Multimaterial 3D Printed Origami Metasurface DOI Creative Commons

Dung Le,

Felix Kronowetter, Yan Kei Chiang

et al.

Advanced Materials Technologies, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 22, 2025

Abstract The challenge in reconfigurable manipulation of sound waves using metasurfaces lies achieving precise control over acoustic behavior while developing efficient and practical tuning methods for structural configurations. However, most studies on rely cumbersome time‐consuming systems. These approaches often struggle with fabrication techniques, as conventional face limitations such restricted material choices, challenges complex geometries, difficulties incorporating flexible components. This paper proposes a novel approach metasurface inspired by the Kresling origami, designed programmable at an operating frequency 2000 Hz. origami unit cell is fabricated multimaterial three‐dimensional (3D) printing technology, allowing simultaneous two materials different mechanical properties, thus creating bistable origami‐based structure. Through optimization, equilibrium states achieve reflection phase difference π through application small axial force, F , or torque, T . Various configurations metasurface, generated from combinations these equilibria, enable distinct reflective behaviors switchable functionalities. principle this work simplifies shaping straightforward mechanism, eliminating need systems adjustments.

Language: Английский

Citations

0
Development of Electrostatic Dual‐Carbon‐Fiber Microgrippers for Precise 2D Patterning and 3D Stacking of Single Microparticles DOI Open Access

MinMing Zai,

Tursunay Yibibulla,

Mohsin Shah

et al.

Small Methods, Journal Year: 2025, Volume and Issue: unknown

Published: March 17, 2025

Abstract This study presents the development of electrostatic dual‐carbon‐fiber (CF) microgrippers for precise manipulation single SiO 2 microparticles (diameters >3 µm) at low operating voltages 5 to 15 V. Theoretical calculations and finite element analysis (FEA) simulations demonstrate that utilize a non‐uniform electric field generated by dual CF electrodes create dielectrophoresis force pick‐and‐place microparticle. After removal turning off voltage, particle release is facilitated van der Waals forces from substrate surface. approach eliminates need additional corona discharge fields or vibrational separators release, ensuring accurate 2D patterning 3D stacking microparticles. The show significant potential applications in individual separation assembly microparticles, such as lunar soil interstellar dust, well single‐cell extraction positioning. Additionally, developed offer broad utility micro/nano‐manufacturing, micro/nano‐electronic circuits, physics, chemistry, biomedicine.

Language: Английский

Citations

0
Manipulation of an acoustically levitated object using externally excited standing waves DOI

M.-R. Akbarzadeh,

Sebastian Oberst, Benjamin Halkon

et al.

The Journal of the Acoustical Society of America, Journal Year: 2025, Volume and Issue: 157(3), P. 1852 - 1861

Published: March 1, 2025

Ultrasonic standing waves can be used to manipulate the position and control movement of levitated objects through acoustic radiation forces. Within this context, theory Gor'kov potential function its contrast factor are revisited, considering scenario a harmonic disturbance wave influence on spherical object. This causes object—trapped within standing, plane ultrasonic field in an ideal fluid—to undergo oscillations sympathy with resulting motion field. In paper, we determine how depends properties object, fluid external excitation, combination. We show that positive, negative, zero forces achieved, causing object pushed towards nearest pressure or velocity node. experimentally verify—through excitation generator—that vibration frequency amplitude transmitted The dependence force reversal novel features employed manipulation for non-contact dynamic characterization small objects.

Language: Английский

Citations

0