Genetic variations related to the prostate cancer risk: A field synopsis and revaluation by Bayesian approaches of genome-wide association studies DOI
André Victor Oliveira Monteiro,

Naum Neves da Costa dos Santos,

J. Silva

et al.

Urologic Oncology Seminars and Original Investigations, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 1, 2024

Language: Английский

Social determinants of health and surgical outcomes of minimally invasive radical prostatectomy: a national population-based study DOI
Spencer Mossack,

Antonio Franco,

Daniel Roadman

et al.

Prostate Cancer and Prostatic Diseases, Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 24, 2024

Language: Английский

Citations

3
Deciphering the Liaison Between Fine Particulate Matter Pollution, Oxidative Stress, and Prostate Cancer: Where Are We Now? DOI Creative Commons

Chiang-Wen Lee,

Yao‐Chang Chiang, Thi Thuy Tien Vo

et al.

Antioxidants, Journal Year: 2024, Volume and Issue: 13(12), P. 1505 - 1505

Published: Dec. 10, 2024

Prostate cancer (PCa), a highly prevalent in men worldwide, is projected to rise the coming years. As emerging data indicate carcinogenic effects of fine particulate matter (PM2.5) lung and other site-specific cancers, there an urgent need evaluate relationship between this environmental risk factor PCa as potential target for intervention. The present review provides up-to-date evidence about impact airborne PM2.5 pollution on initiation progression PCa. Examining composition characteristics reveals its ability induce toxic effects, inflammatory injuries, oxidative damages. Additionally, can attach endocrine-disrupting chemicals implicated prostatic carcinogenesis. Considering significance stress disease, our underlines protective strategies, such antioxidant-based approaches, individuals exposed increased levels. Moreover, findings call further research understand associations mechanisms linking exposure well suggest appropriate measures by policymakers, scientific researchers, healthcare professionals order address global health issue.

Language: Английский

Citations

1
MicroRNA in prostate cancer: from biogenesis to applicative potential DOI Creative Commons
Xu Luo,

Wei Wen

BMC Urology, Journal Year: 2024, Volume and Issue: 24(1)

Published: Nov. 6, 2024

Prostate cancer is the most common solid malignant tumor in men, characterized by high morbidity and mortality. While current screening tools, such as prostate-specific antigen (PSA) testing digital rectal examination, are available for early detection of prostate cancer, their sensitivity specificity limited. Tissue puncture biopsy, although capable offering a definitive diagnosis, has poor positive predictive rates burdens patient more. Therefore, more reliable molecular diagnostic tools urgently need to be developed. In recent years, microRNAs (miRNAs) have attracted much attention research. miRNAs extensively engaged biological processes cell proliferation, differentiation, apoptosis, migration, invasion modulating gene expression post-transcriptionally. Dysregulation miRNA considered critical factor tumorigenesis progression. This review first briefly introduces biogenesis functions then focuses on tumor-promoting tumor-suppressor cancer. Finally, potential application multifunctional prognostic assessment, therapy discussed detail. The concluding section summarizes major points challenges ahead.

Language: Английский

Citations

0
Genetic variations related to the prostate cancer risk: A field synopsis and revaluation by Bayesian approaches of genome-wide association studies DOI
André Victor Oliveira Monteiro,

Naum Neves da Costa dos Santos,

J. Silva

et al.

Urologic Oncology Seminars and Original Investigations, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 1, 2024

Language: Английский

Citations

0