Appropriateness for SARS-CoV-2 vaccination for otolaryngologist and head and neck surgeons in case of pregnancy, breastfeeding, or childbearing potential: Yo-IFOS and CEORL-HNS joint clinical consensus statement DOI Creative Commons
Alberto Maria Saibene, Fabiana Allevi, Tareck Ayad

et al.

European Archives of Oto-Rhino-Laryngology, Journal Year: 2021, Volume and Issue: 278(10), P. 4091 - 4099

Published: April 15, 2021

SARS-CoV-2 vaccines are a key step in fighting the pandemic. Nevertheless, their rapid development did not allow for testing among specific population subgroups such as pregnant and breastfeeding women, or elaborating guidelines healthcare personnel working high infection risk specialties, otolaryngology (ORL). This clinical consensus statement (CCS) aims to offer guidance vaccination this high-risk based on best evidence available. A multidisciplinary international panel of 33 specialists judged statements through two-round modified Delphi method survey. Statements were designed encompass following topics: SARS-Cov-2 use protective equipment ORL; respective risks mother/child dyad; counseling pregnant, breastfeeding, fertile workers (PBFHW). All ORL PBFHW considered target audience. Of 13 statements, 7 reached strong consensus, 2 no near-consensus. According with otorhinolaryngologists-head neck surgeons who childbearing potential should have opportunity receive vaccination. Moreover, personal (PPE) still be used even after Until prospective evaluations these topics available, ORL-HNS must specialty. While PPE remains pivotal, allowed access provided they up-to-date information.

Language: Английский

Safe in Pregnancy and Safe in Children: Global Living Systematic Reviews and Meta-analyses Hub for Emergency Vaccines DOI
Mabel Berrueta, Agustín Ciapponi, Ariel Bardach

et al.

The Pediatric Infectious Disease Journal, Journal Year: 2025, Volume and Issue: 44(2S), P. S111 - S113

Published: Feb. 1, 2025

The coronavirus disease 2019 pandemic encouraged rapid vaccine development, with a fast-evolving evidence base pre- and post-implementation. We developed comprehensive web hub to promote swift information synthesis for present future threats. By expanding our periodically updated living systematic review Chikungunya, Lassa fever, Disease X, we will continuously capture data on safety effectiveness.

Language: Английский

Citations

0
Safe in pregnancy: A global living systematic review and meta-analysis of COVID-19 vaccines in pregnancy DOI
Pierre Buekens, Mabel Berrueta, Agustín Ciapponi

et al.

Vaccine, Journal Year: 2024, Volume and Issue: 42(7), P. 1414 - 1416

Published: Feb. 9, 2024

Language: Английский

Citations

3
Prenatal care providers’ perceptions of the SARS-Cov-2 vaccine for themselves and for pregnant women DOI Creative Commons
Philippe Deruelle,

Camile Couffignal,

Jeanne Sibiude

et al.

PLoS ONE, Journal Year: 2021, Volume and Issue: 16(9), P. e0256080 - e0256080

Published: Sept. 13, 2021

Prenatal care providers will play an important role in the acceptance of SARS-Cov-2 vaccination for pregnant women.To determine perceptions French prenatal providers: midwives, general practitioners (GPs) and obstetricians gynaecologists (Ob-Gyn) regarding SARS-CoV-2 during pregnancy.An anonymous online survey was sent to members professional societies representing practitioners. The participants were asked answer questions on their characteristics give opinions vaccine themselves women who are or willing become pregnant.Access opened from January 11th, 2021, March 1st, 2021. A total 1,416 responses collected 749 Ob-Gyn, 598 midwives 69 GPs. Most respondents (86.7% overall, 90.4% Ob-GYN, 81.1% GPs 80.1% midwives) agreed receive vaccine. Vaccination against would be offered by 49.4% 95%CI [48.1-50.8] participants. Midwives less likely recommend than GP Ob-Gyn (37.5%, 50.7% 58.8%, respectively). multinomial logistic regression revealed that being obstetrician, working a group, usually offering flu wanting vaccinated positively associated with considering vaccination.Most healthcare favourable towards vaccinating women, but large minority express reservation. More evidence safety involvement organisations encourage access SARS-CoV-2.

Language: Английский

Citations

15
Maternal COVID-19 Vaccination and Its Potential Impact on Fetal and Neonatal Development DOI Creative Commons
Niel A. Karrow, Umesh K. Shandilya, Steven Pelech

et al.

Vaccines, Journal Year: 2021, Volume and Issue: 9(11), P. 1351 - 1351

Published: Nov. 18, 2021

Vaccines have been developed under accelerated timelines to combat the COVID-19 pandemic caused by SARS-CoV-2 coronavirus. Although they are considered best approach for preventing mortality, when assessing safety of these vaccines, pregnant women not included in clinical trials. Thus, vaccine this demographic, as well developing fetus and neonate, remains be determined. A global effort has underway encourage get vaccinated despite uncertain risk posed them their offspring. Given this, post-hoc data collection, potentially years, will required determine outcomes vaccination on next generation. Most reactions include injection site erythema, pain, swelling, fatigue, headache, fever lymphadenopathy, which may sufficient affect fetal/neonatal development. In review, we explored components first-generation viral vector mRNA vaccines that believed contribute adverse negatively impact fetal neonatal We followed with a discussion potential using an ovine model explore long-term during prenatal periods.

Language: Английский

Citations

13
A review on COVID-19 transmission, epidemiological features, prevention and vaccination DOI Creative Commons
Yuqin Zhang,

Gonghua Wu,

Shirui Chen

et al.

Medical Review, Journal Year: 2022, Volume and Issue: 2(1), P. 23 - 49

Published: Feb. 1, 2022

Abstract Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused hundreds of millions infections and deaths over past two years. Currently, many countries have still not been able to take the pandemic under control. In this review, we systematically summarized what done mitigate COVID-19 pandemic, from perspectives virus transmission, public health control measures, development vaccination vaccines. As a most likely coming bats, SARS-CoV-2 may transmit among people via airborne, faecal-oral, vertical or foodborne routes. Our meta-analysis suggested that R 0 was 2.9 (95% CI: 2.7–3.1), estimates in Africa Europe could be higher. The median t decrease by 23–96% following nonpharmacological interventions, including lockdown, isolation, social distance, face mask, etc. Comprehensive intervention lockdown were effective measures pandemic. According pooled our meta-analysis, there should at least 93.3% 89.9–96.2%) being vaccinated around world. Limited amount vaccines inequity issues vaccine allocation call for more international cooperation achieve anti-epidemic goals fairness.

Language: Английский

Citations

9
Efficient Maternal to Neonate Transfer of Neutralizing Antibodies after SARS-CoV-2 Vaccination with BNT162b2: A Case-Report and Discussion of the Literature DOI Creative Commons
Jonathan Douxfils, Constant Gillot,

Émilie De Gottal

et al.

Vaccines, Journal Year: 2021, Volume and Issue: 9(8), P. 907 - 907

Published: Aug. 15, 2021

This case reports on the successful maternal to fetal transfer of neutralizing antibodies after vaccination with BNT162b2 in a pregnant woman at 25 weeks gestation. The levels were approximately 5-fold higher umbilical cord than blood while level total showed only 2-fold increase. suggest that crossed syncytiotrophoblast cell barrier have specific characteristics correlate functional capacity. Although and lactating women been excluded from clinical trials for several reasons including ethical concerns about exposure, accumulating evidence has now revealed these vaccines are safe efficient both fetus woman. Vaccination against COVID-19 pregnancy is vital control disease burden decrease morbidity ante-, peri- post-natal periods. Inclusion research programs development SARS-CoV-2 should be mandatory provide this population equitable benefits vaccine research.

Language: Английский

Citations

11
Factors related to COVID-19 vaccination intention and uptake among childbearing women. DOI Creative Commons
Heidi Preis, Brittain Mahaffey, Marci Lobel

et al.

Health Psychology, Journal Year: 2022, Volume and Issue: 42(8), P. 567 - 576

Published: Sept. 8, 2022

Pregnant women are a vulnerable population for coronavirus disease 2019 (COVID-19) due to their risk severe symptoms and adverse perinatal outcomes. Our objective was identify contributors COVID-19 vaccine intention in pregnancy subsequent uptake, informed by the Theory of Planned Behavior, Health Belief Model, paradigms implicating social determinants health (SDoH).

Language: Английский

Citations

8
Evaluation of transplacental transfer of mRNA vaccine products and functional antibodies during pregnancy and early infancy DOI Open Access
Mary Prahl, Yarden Golan, Arianna G. Cassidy

et al.

medRxiv (Cold Spring Harbor Laboratory), Journal Year: 2021, Volume and Issue: unknown

Published: Dec. 13, 2021

Studies are needed to evaluate the safety and effectiveness of mRNA SARS-CoV-2 vaccination during pregnancy, levels protection provided their newborns through placental transfer antibodies. We evaluated transplacental vaccine products functional anti-SARS-CoV-2 antibodies pregnancy early infancy in a cohort 20 individuals vaccinated pregnancy. found no evidence maternal blood, placenta tissue, or cord blood at delivery. However, we time-dependent efficient IgG neutralizing neonate that persisted infancy. Additionally, using phage immunoprecipitation sequencing, vaccine-specific signature Spike protein epitope binding is transplacentally transferred In conclusion, vaccines not fetus however timing critical ensure protective

Language: Английский

Citations

10
SARS-CoV-2, Zika viruses and mycoplasma: Structure, pathogenesis and some treatment options in these emerging viral and bacterial infectious diseases DOI Creative Commons
Gonzalo Ferreira, Axel Santander, Florencia Savio

et al.

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, Journal Year: 2021, Volume and Issue: 1867(12), P. 166264 - 166264

Published: Sept. 3, 2021

Language: Английский

Citations

8
Perceptions and Attitudes Towards COVID-19 Vaccination Amongst Pregnant and Postpartum Individuals DOI Open Access
Molly Siegel, Mario I. Lumbreras-Márquez, Kaitlyn E. James

et al.

medRxiv (Cold Spring Harbor Laboratory), Journal Year: 2021, Volume and Issue: unknown

Published: Dec. 18, 2021

Abstract Introduction This study aims to characterize attitudes towards COVID-19 vaccination and evaluate factors associated with vaccine uptake amongst pregnant individuals. Methods An anonymous survey was distributed a convenience sample of individuals receiving prenatal care at two large urban academic hospitals in single healthcare network Massachusetts. Individual demographic variables were included the along questions assessing pregnancy. Results Of 477 respondents, 233 (49.3%) had received or scheduled receive vaccine. Age, White race, non-Hispanic/LatinX ethnicity, working from home, typical receipt influenza vaccination. 276 respondents (58.4%) reported that their provider recommended pregnancy; these participants more likely have (OR 5.82, 95% confidence interval [CI] 3.68-9.26). Vaccinated less be worried about effects on themselves 0.18, CI 0.12-0.27) developing babies 0.17, 0.11-0.26). Unvaccinated report it is easy schedule 0.56, 0.34-0.93), travel 0.19, 0.10-0.36), miss work 0.30, 0.18-0.48). Conclusions Strategies are needed improve patient education regarding side safety pregnancy change policy make feasible for patients without loss pay get vaccinated. Key Points There racial ethnic disparities concerned growing babies. cited scheduling-related barriers vaccination, indicating areas advocacy

Language: Английский

Citations

6