Global Analysis of RTS, S/AS01 Malaria Vaccine Acceptance Rates and Influencing Factors: A Systematic Review DOI Open Access
Farrukh Ansar,

Abdullah Azzam,

Mohammad S Rauf

et al.

Cureus, Journal Year: 2024, Volume and Issue: unknown

Published: May 20, 2024

Malaria remains a significant global health challenge, with Plasmodium parasites transmitted by Anopheles mosquitoes causing substantial morbidity and mortality. Despite historical efforts, malaria continues to affect millions worldwide, particularly in tropical regions. This systematic review aimed assess the acceptability of RTS, S/AS01 vaccine among diverse populations. A comprehensive search strategy was employed across databases such as Cochrane Library, Embase, Google Scholar, Medline. Studies were included based on specific criteria, including observational cross-sectional designs involving adults. Data extraction analysis conducted meticulously, encompassing key variables related acceptance rates influencing factors. Analysis 18 studies 18,561 participants revealed an overall rate 87.51%, ranging from 32.26% 99.30%. Significant variations observed demographics, Ghana Nigeria reporting high rates. Factors knowledge levels, past vaccination experiences, community preferences, engagement prevention behaviors. Concerns about adverse reactions regional disparities noted potential barriers acceptance. highlights importance understanding public perceptions concerns regarding vaccines enhance coverage uptake. Tailored communication strategies, advocacy targeted education interventions are crucial for addressing misconceptions increasing Policy recommendations should consider demographic factors ensure effective implementation programs, ultimately contributing efforts initiatives.

Language: Английский

High Intention to Vaccinate Against Tuberculosis During Pregnancy and Lactation: Understanding Vaccine-specific Maternal Immunization Acceptance in Amhara, Ethiopia DOI
Elizabeth Quincer, Abebe Gebremariam Gobezayehu, Mulusew Lijalem Belew

et al.

The Pediatric Infectious Disease Journal, Journal Year: 2025, Volume and Issue: 44(2S), P. S135 - S140

Published: Feb. 1, 2025

Background: Tuberculosis (TB) disease during pregnancy results in adverse maternal and infant outcomes. The development of a TB vaccine with potential for administration or lactation is priority identified by the World Health Organization. We assessed acceptability vaccines currently administered [tetanus, diphtheria COVID-19] willingness to receive new and/or among Ethiopian women. Methods: From January February 2022, we conducted surveys pregnant women receiving antenatal care at 20 hospitals Amhara, Ethiopia. evaluated uptake available (diphtheria), acceptance future (COVID-19 TB) lactation, knowledge, attitudes beliefs associated vaccine-specific acceptance. Results: Among 200 participants, found high intention (90%) (92%) low COVID-19 (40%) (47%). Most participants believed vaccination would protect their child from (82.5%) have societal benefits (81.5%), while few perceived offer protection (35.5%) (42.5%). Intention was belief that prevent infants (adjusted prevalence ratio 1.37, 95% CI: 1.10–1.70). reported educational interventions increase immunization. Conclusions: Our findings support strengthen immunization programs

Language: Английский

Citations

0
Factors influencing vaccine hesitancy toward non-covid vaccines in South Asia: a systematic review DOI Creative Commons

Sophie C W Stuetzle,

Matthew Willis,

Ewelina Julia Barnowska

et al.

BMC Public Health, Journal Year: 2025, Volume and Issue: 25(1)

Published: April 2, 2025

Abstract Declared as one of the ten most pressing threats to global health in 2019, complexity around vaccine acceptance and hesitancy has once again gained great momentum following COVID-19 pandemic. Lack may endanger mission improving uptake globally tackle pandemics, reduce morbidity mortality preventable diseases prevent antibiotic resistance worldwide. Countries south, including South Asian Association for Regional Cooperation (SAARC) countries are especially affected by dangers low vaccination continue show decreases coverage recent years. This paper examines factors contributing south Asia extent which they context disease specific, guided a modified version WHO SAGE 5 C model Razai et al. Three databases were searched peer-reviewed articles using comprehensive search strategy. Results from 44 quantitative, qualitative mixed-method studies included systematic review appraised quality, thematically analyzed mapped onto model. findings India, Pakistan, Bangladesh, Nepal Afghanistan showed be vaccine-specific within different settings countries. The main can identified narrow confidence vaccines, miscommunication, lack knowledge embedded into overarching constraints contexts. To SAARC countries, interventions need co-created communities mutual trust needs ensured, instance through increased equity distribution.

Language: Английский

Citations

0
The global burden of enteric fever, 2017–2021: a systematic analysis from the global burden of disease study 2021 DOI Creative Commons
Daniele Piovani, Gisella Figlioli, Georgios K. Nikolopoulos

et al.

EClinicalMedicine, Journal Year: 2024, Volume and Issue: 77, P. 102883 - 102883

Published: Oct. 18, 2024

Language: Английский

Citations

2
Global Analysis of RTS, S/AS01 Malaria Vaccine Acceptance Rates and Influencing Factors: A Systematic Review DOI Open Access
Farrukh Ansar,

Abdullah Azzam,

Mohammad S Rauf

et al.

Cureus, Journal Year: 2024, Volume and Issue: unknown

Published: May 20, 2024

Malaria remains a significant global health challenge, with Plasmodium parasites transmitted by Anopheles mosquitoes causing substantial morbidity and mortality. Despite historical efforts, malaria continues to affect millions worldwide, particularly in tropical regions. This systematic review aimed assess the acceptability of RTS, S/AS01 vaccine among diverse populations. A comprehensive search strategy was employed across databases such as Cochrane Library, Embase, Google Scholar, Medline. Studies were included based on specific criteria, including observational cross-sectional designs involving adults. Data extraction analysis conducted meticulously, encompassing key variables related acceptance rates influencing factors. Analysis 18 studies 18,561 participants revealed an overall rate 87.51%, ranging from 32.26% 99.30%. Significant variations observed demographics, Ghana Nigeria reporting high rates. Factors knowledge levels, past vaccination experiences, community preferences, engagement prevention behaviors. Concerns about adverse reactions regional disparities noted potential barriers acceptance. highlights importance understanding public perceptions concerns regarding vaccines enhance coverage uptake. Tailored communication strategies, advocacy targeted education interventions are crucial for addressing misconceptions increasing Policy recommendations should consider demographic factors ensure effective implementation programs, ultimately contributing efforts initiatives.

Language: Английский

Citations

1