Sensitization Patterns to Aeroallergens and Food Allergens Among Children with Atopic Asthma in Southwestern Saudi Arabia DOI Creative Commons
Ali Alsuheel Asseri,

Mashael Abdualslam Abuaqil,

Abdulaziz Alotaibi

et al.

Children, Journal Year: 2025, Volume and Issue: 12(5), P. 573 - 573

Published: April 29, 2025

Background and Objectives: Asthma is a prevalent chronic respiratory disease in children, with increasing rates Saudi Arabia. Allergen sensitization plays crucial role asthma development severity. This study aimed to investigate the prevalence clinical impact of aeroallergen food children Southwestern Materials Methods: A retrospective chart review was conducted at Abha Maternity Children’s Hospital, including 194 aged 3–12 years atopic asthma. Sensitization 26 common aeroallergens allergens assessed using EUROLINE Allergy test. Associations between patterns, comorbidities (allergic rhinitis eczema), asthma-related outcomes (hospitalizations, medication use, school absenteeism) were analyzed. Results: high observed (74.2% for aeroallergens; 56.7% allergens). Aeroallergen associated older age (p < 0.001), male sex = 0.026), allergic eczema 0.295), increased morbidity, hospitalizations 0.002) corticosteroid use 0.012). Food 0.001) but did not significantly other outcomes. Poly-sensitization higher 0.003). Dust mite strong independent predictor severe (adjusted odds ratio 4.4, 95% CI 1.7–11.8, p Conclusions: demonstrates among Arabia, distinct patterns comorbidities. sensitization, particularly dust mites, highlighting importance comprehensive assessment this population. While limited by its design, provides valuable insights into interplay childhood asthma, informing future research practice.

Language: Английский

The global burden and trends of asthma from 1990 to 2021, and its changes during the COVID-19 pandemic: An observational study DOI Creative Commons
Xiaofang Fu,

Danruo Fang,

Minjie Ge

et al.

Public Health, Journal Year: 2025, Volume and Issue: 241, P. 47 - 54

Published: Feb. 12, 2025

Language: Английский

Citations

0
Obesity in severe asthma: Unveiling challenges and exploring new therapeutic options DOI Creative Commons
Mona Al‐Ahmad, Asmaa Ali

World Allergy Organization Journal, Journal Year: 2025, Volume and Issue: 18(4), P. 101042 - 101042

Published: March 13, 2025

Language: Английский

Citations

0
Prevalence and associated factors of pediatric uncontrolled asthma in Vietnam DOI
Ly Cong Tran, Nguyen Minh Phuong, Nghia Quang Bui

et al.

Journal of Asthma, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 16

Published: March 21, 2025

Uncontrolled asthma profoundly affects quality of life and imposes a significant societal burden. However, reports on its prevalence contributing factors in Vietnam remain limited. This study aimed to address this gap by investigating the associated with uncontrolled among children Vietnam. An analytical cross-sectional was conducted involving 344 pediatric patients their caregivers. The Childhood Asthma Control Test (C-ACT) (ACT) were used assess control aged 4-11 12-16 years, respectively. Data patient, caregiver, treatment characteristics collected for analysis. Logistic regression analysis employed identify asthma. 40.1%. Factors significantly included previous admissions due (aOR = 2.80, 95% CI: 1.56 - 5.04, P < 0.001), inadequate caregiver knowledge 2.86, 5.19, non-adherence controller medication 1.92, 1.07 3.48, 0.030). Vietnamese is quite high. Previous asthma, knowledge, identified as

Language: Английский

Citations

0
Inflammatory mediators in nasal secretion in patients with bronchial asthma and allergic rhinitis with or without polyposis and hypertrophic sinonasal mucosa DOI Creative Commons
S.V. Krasilnikova,

Ekaterina Ivanovna Krestova,

Т.И. Елисеева

et al.

Exploration of Medicine, Journal Year: 2025, Volume and Issue: unknown

Published: April 17, 2025

Aim: The pathogenetic mechanisms and predictors of the development polyposis hypertrophy sinonasal mucosa (SM) in patients with chronic allergic airway inflammation have not been clearly established. concentration inflammatory biomarkers nasal secretions was determined children adolescents a combined course bronchial asthma (BA) rhinitis (AR) absence or presence SM. Methods: A single-centre observational cross-sectional pilot study conducted. 93 BA aged 8 to 17 years were studied. Total Nasal Symptom Score (TNSS), symptoms (SNOT-22), peak inspiratory flow (PNIF) assessed. Concentrations eosinophil cationic protein (ECP), interleukin 4 (IL-4), IL-1, total immunoglobulin E (IgE), vascular endothelial growth factor (VEGF) determined. Results: levels ECP, IL-4, IL-1 statistically significantly higher hypertrophic SM than those without, amounting 83.1 [31.4; 166.8] ng/mL for ECP vs. 29.5 [5.3; 49.9] ng/mL, P < 0.001, IL-4 174.6 [68.6; 325.5] pg/mL 79.5 [42.8; 146.01] pg/mL, = 0.004, 98.7 [33.7; 267.5] 48.8 [9.01; 108.2] 0.025. There no significant differences IgE VEGF secretions, all > 0.05. Parameters such as found be formation Conclusions: In AR, is associated secretion. This may indicate that pathological remodelling both intensity its relationship local activation innate immunity.

Language: Английский

Citations

0
Sensitization Patterns to Aeroallergens and Food Allergens Among Children with Atopic Asthma in Southwestern Saudi Arabia DOI Creative Commons
Ali Alsuheel Asseri,

Mashael Abdualslam Abuaqil,

Abdulaziz Alotaibi

et al.

Children, Journal Year: 2025, Volume and Issue: 12(5), P. 573 - 573

Published: April 29, 2025

Background and Objectives: Asthma is a prevalent chronic respiratory disease in children, with increasing rates Saudi Arabia. Allergen sensitization plays crucial role asthma development severity. This study aimed to investigate the prevalence clinical impact of aeroallergen food children Southwestern Materials Methods: A retrospective chart review was conducted at Abha Maternity Children’s Hospital, including 194 aged 3–12 years atopic asthma. Sensitization 26 common aeroallergens allergens assessed using EUROLINE Allergy test. Associations between patterns, comorbidities (allergic rhinitis eczema), asthma-related outcomes (hospitalizations, medication use, school absenteeism) were analyzed. Results: high observed (74.2% for aeroallergens; 56.7% allergens). Aeroallergen associated older age (p < 0.001), male sex = 0.026), allergic eczema 0.295), increased morbidity, hospitalizations 0.002) corticosteroid use 0.012). Food 0.001) but did not significantly other outcomes. Poly-sensitization higher 0.003). Dust mite strong independent predictor severe (adjusted odds ratio 4.4, 95% CI 1.7–11.8, p Conclusions: demonstrates among Arabia, distinct patterns comorbidities. sensitization, particularly dust mites, highlighting importance comprehensive assessment this population. While limited by its design, provides valuable insights into interplay childhood asthma, informing future research practice.

Language: Английский

Citations

0