Mechanistic Insights into the Sequestration of Antibiotics in Aquatic Sediments and the Microbial Phylogenetic Divergence between the Aqueous and Sediment Phases on the Fate of Antibiotic Resistance Genes

Published: Jan. 1, 2023

Antibiotic pollution and the evolution of antibiotic resistance genes (ARGs) are critical issues global significance. This study investigated sequestration antibiotics onto aquatic sediments microbial phylogenetic divergence between aqueous sedimentary phases on resistome profiles. The total concentration in surface water (49.5%) was significantly higher than suspended particulate matter (31.4%), sedimental (19.1%). However, relative abundance ARGs sediment disproportionate to concentration, were predominant reservoirs. Phylogenetic communities ecosystems resulted a significant shift profiles two distinctive surface-water sediments. Priority Clinical importance; blaGES, MCR-7.1, ermB, tet(34), tet36, tetG-01, sul2 increased water, while blaCTX-M-01, blaTEM, blaOXA10-01, blaVIM, tet(W/N/W), tetM02, ermX amplified cfxA an endemic ARG included aacC4, aadA9-02, blaCTX-M-04, blaIMP-01, blaIMP-02, bla-L1, penA, erm(36), ermC, ermT-01, msrA-01, pikR2, vgb-01, mexA, oprD, ttgB, aac. These findings provide crucial information for identification ARGs-specific high-risk reservoirs

Language: Английский

Microbial Phylogenetic Divergence between Surface-Water and Sedimentary Ecosystems Drove the Resistome Profiles

Published: Jan. 1, 2023

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Language: Английский