Wastewater surveillance in post-omicron silent phase uncovers silent waves and cryptic transmission of SARS-CoV-2 variants; a yearlong study in Western India DOI
Vinay Rajput, Rinka Pramanik,

Kiran Nannaware

et al.

The Science of The Total Environment, Journal Year: 2024, Volume and Issue: 955, P. 176833 - 176833

Published: Oct. 11, 2024

Language: Английский

In-sewer stability assessment of 140 pharmaceuticals, personal care products, pesticides and their metabolites: Implications for wastewater-based epidemiology biomarker screening DOI Creative Commons
Jiaqi Wen, Lei Duan, Bin Wang

et al.

Environment International, Journal Year: 2024, Volume and Issue: 184, P. 108465 - 108465

Published: Jan. 30, 2024

The monitoring of pharmaceuticals, personal care products (PCPs), pesticides, and their metabolites through wastewater-based epidemiology (WBE) provides timely information on pharmaceutical consumption patterns, chronic disease treatment rates, antibiotic usage, exposure to harmful chemicals. However, before applying them for quantitative WBE back-estimation, it is necessary understand stability in the sewer system screen suitable biomarkers thereby reducing research uncertainty. This study investigated in-sewer 140 typical PCPs, across 15 subcategories, using a series laboratory sediment biofilm reactors. For first time, results 89 these compounds were reported. Among target compounds, 61 demonstrated high all reactors, while 41 significantly removed merely by processes. exhibiting notable attenuation, influence processes was generally more pronounced than biofilm, due its stronger microbial activities diffusion or adsorption Adsorption emerged as predominant factor causing biomarker removal compared biodegradation diffusion. Significantly different organic carbon-water partitioning coefficient (K

Language: Английский

Citations

12
Influent wastewater analysis to investigate emerging trends of new psychoactive substances use in Europe DOI
Noelia Salgueiro‐González, Frederic Béen, Lubertus Bijlsma

et al.

Water Research, Journal Year: 2024, Volume and Issue: 254, P. 121390 - 121390

Published: Feb. 27, 2024

Language: Английский

Citations

11
A dual action electrochemical molecular imprinting sensor based on FeCu-MOF and RGO/PDA@MXene hybrid synergies for trace detection of ribavirin DOI
Haifeng Gao,

Junyi You,

Hongbo Wu

et al.

Food Chemistry, Journal Year: 2025, Volume and Issue: unknown, P. 143092 - 143092

Published: Jan. 1, 2025

Language: Английский

Citations

1
Aptamer-based biosensors for wastewater surveillance of influenza virus, SARS-CoV-2, and norovirus: A comprehensive review DOI Creative Commons
Yilei Wang, Mohan Amarasiri, Wakana Oishi

et al.

Water Research, Journal Year: 2025, Volume and Issue: unknown, P. 123484 - 123484

Published: March 1, 2025

Wastewater-based epidemiological (WBE) surveillance has emerged as a crucial tool for monitoring infectious diseases within communities. However, its broader application is frequently constrained by the high costs, labor-intensive processes, and extended timeframes required sample collection, transportation, processing. Aptamer-based biosensors offer promising alternative, leveraging specific binding properties of aptamers to biomolecules on-site rapid quantification disease biomarkers in wastewater. This review systematically evaluates recent advancements aptamer-based detection key pathogens, including influenza viruses, SARS-CoV-2, norovirus, wastewater matrices. The discussion encompasses technical stability reliability signal transmission associated with these biosensors, well current challenges faced real-world implementation. Noteworthy progress been made development WBE, achieving limits low femtomolar (fM) levels buffer linear dynamic ranges extending up five orders magnitude viruses such SARS-CoV-2. Despite this progress, considerable hurdles remain be addressed before technologies can effectively deployed practical settings, especially complex environments. Key factors affecting performance include matrix interference, environmental variability, diminished both viral targets aptamer-target interactions not only highlights but also outlines potential avenues future research aimed at enhancing functionality applicability ultimately contributing more effective public health strategies.

Language: Английский

Citations

1
Chlorination of antiviral drug ribavirin: Kinetics, nontargeted identification, and concomitant toxicity evolution DOI

Kehui Guo,

Yang Liu, Jianfeng Peng

et al.

Journal of Hazardous Materials, Journal Year: 2024, Volume and Issue: 467, P. 133478 - 133478

Published: Jan. 9, 2024

Language: Английский

Citations

7
Favipiravir biotransformation by a side-stream partial nitritation sludge: Transformation mechanisms, pathways and toxicity evaluation DOI
Yifeng Xu, Yaxuan Liu, Chuanzhou Liang

et al.

Chemosphere, Journal Year: 2024, Volume and Issue: 353, P. 141580 - 141580

Published: Feb. 29, 2024

Language: Английский

Citations

6
Degradation and ecotoxicity of favipiravir and oseltamivir in the presence of microplastics during ozonation and catalytic ozonation of synthetic municipal wastewater effluents DOI Creative Commons
Serdar Doǧruel,

Nasim Chavoshi,

Nilay Bilgin‐Saritas

et al.

Journal of Chemical Technology & Biotechnology, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 20, 2025

Abstract Background Favipiravir (FAV) and oseltamivir (OSE) are antiviral agents developed against influenza they were repurposed SARS‐CoV‐2 during the COVID‐19 pandemic. This study evaluated potential of ozonation catalytic as tertiary treatment approaches for removing FAV OSE from municipal wastewaters, both in presence absence microplastics (MPs), while comparing ecotoxicity untreated treated secondary effluents to predict ecotoxicological effects these technologies wastewater treatment. Results At an initial concentration 50 μg L −1 , at pH 7 with a specific ozone dose 0.6 mg O 3 (mg DOC) yielded removals 84 64%, respectively, catalyst or MPs decreased degradation rate by 30–40%. Raising 10 had minimal impact on abatement, but improved reduction 21%. Acute toxicity tests using Vibrio fischeri demonstrated that simultaneous analytes led accumulation transformation products (TPs) OSE, their combined effect almost equal original compounds. Reproduction indicated TPs drugs generated less toxic Enchytraeus crypticus than parent chemicals. Conclusion Ozonation proved be viable option upgrading existing facilities, serving complementary minimize release antivirals reduce inhibitory earthworm reproduction, thereby enhancing reuse irrigation. © 2025 The Author(s). Journal Chemical Technology Biotechnology published John Wiley & Sons Ltd behalf Society Industry (SCI).

Language: Английский

Citations

0
Could chloroxylenol be used as WBE biomarker in gravity sewers? Fates, behaviors and feasible conditions DOI

Xinhui Xia,

Huizhi Mu,

Yujia Du

et al.

Water Research, Journal Year: 2025, Volume and Issue: 278, P. 123376 - 123376

Published: Feb. 25, 2025

Language: Английский

Citations

0
A novel data-driven screening method of antidepressants stability in wastewater and the guidance of environmental regulations DOI Creative Commons

Peixuan Sun,

Huaishi Liu, Yuanyuan Zhao

et al.

Environment International, Journal Year: 2025, Volume and Issue: unknown, P. 109427 - 109427

Published: March 1, 2025

Wastewater-based epidemiology (WBE) represents a powerful technique for quantifying the attenuation characteristics and consumption of pharmaceuticals. In addition to WBE, no further methods have been developed assess wastewater stability related antidepressants (ADs). this study, biodegradability, solubility, adsorption or partition 66 ADs were objectively scored according relevant guidelines Organisation Economic Cooperation Development. An assessment framework MSSL-RealFormer classification model constructed based on physicochemical properties predict quantitative structure-activity relationship. The exhibited markedly higher prediction accuracy than traditional methods. Furthermore, 15 high-stable in with low high identified. SHapley Additive exPlanation method demonstrated that group hydrophobicity, electrostatic van der Waals forces exerted significant influence stability. And molecular was found be significantly correlated A combination density functional theory employed identify 17 transformation products nine medium- low-stable wastewater. Ecological Structure Activity Relationships bupropion, tapentadol chlorpheniramine acute toxicity aquatic food chain. novel deep learning rapidly screen correlation between their structures. It is anticipated prove favorable tool optimizing screening

Language: Английский

Citations

0
In-sewer stability of 31 human health biomarkers and suitability for wastewater-based epidemiology DOI Creative Commons
Jiaying Li, Phil M. Choi, Jianfa Gao

et al.

Water Research, Journal Year: 2023, Volume and Issue: 249, P. 120978 - 120978

Published: Dec. 5, 2023

Monitoring urinary markers of dietary, disease, and stress by wastewater-based epidemiology (WBE) is a promising tool to better understand population health wellbeing. However, common biomarkers are subject degradation in sewer systems their fates have be assessed before they can used WBE. This study investigated the stability 31 (12 food biomarkers, 8 vitamins, 9 oxidative 1 histamine biomarker) laboratory sediment reactor evaluated suitability for WBE, considering detectability real wastewater in-sewer stability. These showed various transformation patterns, among which 16 compounds had half-lives <2 h while other 15 presented moderate high (2 >500 h). Thirteen potential WBE because consistently measurable concentrations untreated sufficient Eighteen were unsuitable due rapid and/or undetectable concentration levels using previous methods. Transformation rates these generally weak relationships with molecular properties but relatively higher correlations biological activities sewers. Overall, this determined health-related through experiments, providing new findings assessment.

Language: Английский

Citations

6