A Review of Wastewater-Based Epidemiology for the SARS-CoV-2 Virus in Rural, Remote, and Resource-Constrained Settings Internationally: Insights for Implementation, Research, and Policy for First Nations in Canada DOI Open Access
Joe-Steve Annan, Rita Henderson, Mandi Gray

et al.

International Journal of Environmental Research and Public Health, Journal Year: 2024, Volume and Issue: 21(11), P. 1429 - 1429

Published: Oct. 28, 2024

Wastewater-based epidemiology (WBE) is regarded as a support tool for detecting and assessing the prevalence of infectious diseases at population level. For rural, remote, resource-constrained communities with little access to other public health monitoring tools, WBE can be low-cost approach filling gaps in knowledge inform risk assessment decision-making. This rapid review explores discusses unique considerations key settings, focus on detection SARS-CoV-2 virus, which has rapidly expanded infrastructure globally. To frame our understanding possibilities First Nations Alberta, we address following questions: What are challenges under similar contexts or settings? resources expertise required WBE? identifies several communities, including costs, accessibility, operator capacity, wastewater infrastructure, data mobilization—highlighting need equity WBE. In summary, most require additional from external research and/or governmental bodies undertake

Language: Английский

Small-scale wastewater-based epidemiology (WBE) for infectious diseases and antibiotic resistance: A scoping review DOI Creative Commons
Dennis Schmiege, Timo Haselhoff, A. G. R. Thomas

et al.

International Journal of Hygiene and Environmental Health, Journal Year: 2024, Volume and Issue: 259, P. 114379 - 114379

Published: April 15, 2024

Wastewater analysis can serve as a source of public health information. In recent years, wastewater-based epidemiology (WBE) has emerged and proven useful for the detection infectious diseases. However, insights from wastewater treatment plant do not allow small-scale differentiation within sewer system that is needed to analyze target population under study in more detail. Small-scale WBE offers several advantages, but there been no systematic overview its application. The aim this scoping review provide comprehensive current state knowledge on diseases, including methodological considerations A database search was conducted, considering only peer-reviewed articles. Data analyses included quantitative summary qualitative narrative synthesis. Of 2130 articles, we 278, most which were published since 2020. studies analyzed at building level (n = 203), especially healthcare 110) educational facilities 80), neighborhood scale 86). main analytical parameters viruses 178), notably SARS-CoV-2 161), antibiotic resistance (ABR) biomarkers 99), often by polymerase chain reaction (PCR), with DNA sequencing techniques being less common. terms sampling techniques, active dominated. frequent lack detailed information specification selection criteria characterization sites identified concern. conclusion, based large number studies, overarching strategic aspects WBE. An enabling environment requires inter- transdisciplinary sharing across countries. Promoting adoption will benefit common international conceptualization approach, standardized internationally accepted terminology. particular, development good practices different warranted. This includes establishment guidelines local sub-sewersheds, transparent reporting ensure comparability results.

Language: Английский

Citations

7
Subsewershed Analyses of the Impacts of Inflow and Infiltration on Viral Pathogens and Antibiotic Resistance Markers Across a Rural Sewer System DOI
Amanda Darling, Benjamin C. Davis,

Thomas Byrne

et al.

Water Research, Journal Year: 2025, Volume and Issue: 276, P. 123230 - 123230

Published: Jan. 30, 2025

Language: Английский

Citations

0
Sub-national estimation of surveillance sensitivity to inform declaration of disease elimination DOI Creative Commons
Emily Nightingale,

Ly Pham-Minh,

Isah Mohammed Bello

et al.

medRxiv (Cold Spring Harbor Laboratory), Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 31, 2025

Abstract A fundamental question in the global commitment to polio eradication is how long a period of absence would be consistent with regional elimination, and safe withdrawal oral vaccine contingent on answer. We present statistical framework estimate time-varying sensitivity two key components surveillance - environmental sampling clinical cases acute flaccid paralysis for detecting infection at local government authority level. probability freedom from (FFI) critical prevalence level that interruption transmission, given virus collected samples. validated this against periods poliovirus Nigeria (2014-2016 2016-2020). observed substantial heterogeneity over time space and, this, concluded an 85% (95% uncertainty interval: 77.1-90.2%) country being free WPV1 after 23 months without detection July 2014. Detection 2016 demonstrated circulation had indeed persisted during time. In contrast, we conclude 98% (97.9-98.7%) by elimination serotype was officially declared 2020. The inferred FFI both found retrospectively known status elimination. This supports validity applying prospectively inform certification wild remaining endemic regions, determine resolution cVDPV2 outbreaks.

Language: Английский

Citations

0
COVID-19 Risk and Crisis Communication Challenges and Opportunities: Qualitative Insights from Rural Wastewater Surveillance Partners DOI
Sharon Tucker, Beverly May, Matthew Liversedge

et al.

Disaster Medicine and Public Health Preparedness, Journal Year: 2025, Volume and Issue: 19

Published: Jan. 1, 2025

Abstract Objectives Understand perceptions of COVID-19 messages and information sources among rural wastewater treatment plant operators to inform context-specific communication strategies for implementing surveillance methodologies locally. Methods Eight employees from 7 Eastern Kentucky facilities involved in SARS-CoV-2 participated semi-structured interviews. Respondents shared traditional social media channels their communities, as well factors influencing trustworthiness sources. Using the U.S. Centers Disease Control Prevention’s Crisis Emergency Risk Communication (CERC) framework, 3 investigators conducted iterative, thematic coding interview transcripts. Results Respondents’ statements most frequently related “Be Credible,” Right,” “Promote Action” CERC constructs, while mixed messages, high volumes information, numerous undermined trust information. Conclusions Understanding relative importance constructs distractors may improve future risk advance infectious disease contexts.

Language: Английский

Citations

0
Tracking COVID-19 trends in communities with low population by wastewater-based surveillance DOI Creative Commons

Aiswarya Rani Pappu,

Ashley Green,

Michael Oakes

et al.

The Science of The Total Environment, Journal Year: 2025, Volume and Issue: 970, P. 179007 - 179007

Published: March 1, 2025

Wastewater-based surveillance (WBS) of SARS-CoV-2 is increasingly recognized as a valuable complement to clinical reporting for estimating COVID-19 infection rates. This acceptance stems from the strong correlation found between wastewater and case data during early stages pandemic. However, cessation restrictions, changes in testing requirements by late 2021, widespread use take-home antigen tests have diminished reliability volume clinically reported counts. study explores dynamics cases wastewater-based results period transition, focusing on student residential areas within university campus. We analyzed 13 sub-sewersheds, serving populations 300 4000 individuals, three times weekly December 2021 June 2022. The analysis revealed two spikes this time, whereas reports indicated at most single surge infections across communities. Further, first surge, plateaued sooner than trends and, second either lagged or were completely absent. Correlations concentrations 3-day rolling average weak smaller communities (≤1000 people) but improved with larger community sizes (>1000 people). Normalization PMMoV did not enhance these correlations. Given challenges executing accurate mass testing, our findings advocate efficacy WBS reliably forecasting surges, even less populous settings, thereby facilitating swift, informed public health interventions.

Language: Английский

Citations

0
SARS-CoV-2 Surveillance of Wastewater in Small Rural Communities Identifies Lack of Vaccine Coverage as Influence of Omicron Outbreak DOI
Solana Narum, Thibault Stalder, Benjamin J. Ridenhour

et al.

Water Research, Journal Year: 2025, Volume and Issue: unknown, P. 123818 - 123818

Published: May 1, 2025

Language: Английский

Citations

0
A Review of Wastewater-Based Epidemiology for the SARS-CoV-2 Virus in Rural, Remote, and Resource-Constrained Settings Internationally: Insights for Implementation, Research, and Policy for First Nations in Canada DOI Open Access
Joe-Steve Annan, Rita Henderson, Mandi Gray

et al.

International Journal of Environmental Research and Public Health, Journal Year: 2024, Volume and Issue: 21(11), P. 1429 - 1429

Published: Oct. 28, 2024

Wastewater-based epidemiology (WBE) is regarded as a support tool for detecting and assessing the prevalence of infectious diseases at population level. For rural, remote, resource-constrained communities with little access to other public health monitoring tools, WBE can be low-cost approach filling gaps in knowledge inform risk assessment decision-making. This rapid review explores discusses unique considerations key settings, focus on detection SARS-CoV-2 virus, which has rapidly expanded infrastructure globally. To frame our understanding possibilities First Nations Alberta, we address following questions: What are challenges under similar contexts or settings? resources expertise required WBE? identifies several communities, including costs, accessibility, operator capacity, wastewater infrastructure, data mobilization—highlighting need equity WBE. In summary, most require additional from external research and/or governmental bodies undertake

Language: Английский

Citations

0