Environmental Research, Journal Year: 2024, Volume and Issue: 263, P. 120051 - 120051
Published: Sept. 23, 2024
Language: Английский
Water Research, Journal Year: 2025, Volume and Issue: 274, P. 123092 - 123092
Published: Jan. 4, 2025
Chlorine, the most widely utilized disinfectant for drinking water globally, has recently been implicated in facilitating spread of antibiotic resistance genes (ARGs), raising concerns about its underestimated environmental and ecological risks. However, given current fragmented research focus results, a comprehensive understanding potential mechanisms influencing factors behind chlorination-promoted ARGs transmission systems is crucial. This work first to systematically review variations abundance, mechanisms, factors, mitigation strategies related during chlorination process. The results indicated that could induce genetic mutations promote horizontal gene transfer through multiple pathways, including increased reactive oxygen species, enhanced membrane permeability, stimulation SOS response, activation efflux pumps. In addition, this delves into significant discoveries regarding affecting ARG water, such as chlorine concentration, reaction time, disinfection byproducts, pipe materials, biofilms, matrix. A series effective from source point-of-use were proposed aimed at mitigating risks system. Finally, we address existing challenges outline future directions overcome these bottlenecks. Overall, aims advance our role dissemination inspire innovative ideas optimizing techniques, minimizing transmission, enhancing safety water.
Language: Английский
Citations
3
Bacteria, Journal Year: 2025, Volume and Issue: 4(1), P. 8 - 8
Published: Feb. 4, 2025
Members of the Dolichocephalovirinae subfamily are giant viruses with an elongated head and a flexible tail that is used to infect Caulobacter strains. In this paper, we describe isolation characterization nine newly isolated phages present evidence seven these represent new genus has significant differences from four previously described genera. addition, since were single sampling site over course three years, comparison their genome sequences reveals low level within-population diversity resulting both single-nucleotide polymorphisms insertions or deletions. A host ranges suggests in susceptibility may be important factor maintaining diversity.
Language: Английский
Citations
1
Toxicology Reports, Journal Year: 2025, Volume and Issue: 14, P. 101969 - 101969
Published: Feb. 22, 2025
Language: Английский
Citations
1
Environments, Journal Year: 2025, Volume and Issue: 12(3), P. 96 - 96
Published: March 18, 2025
The interaction between antibiotics and antibiotic resistance genes (ARGs) in freshwater ecosystems has become a critical environmental concern. This study investigates seasonal variations of sulfonamide tetracycline their relationship with ARGs three urban reservoirs Nanjing, China: Pingshan Forest Park, Shanhu Lake Wetland Zhaoqiao Reservoir. Sampling was conducted May September 2023 to assess water quality, concentrations, ARG abundance. A total 30 samples were analyzed regard physicochemical parameters, heavy metals, antibiotics. quantitative PCR assay used measure the abundance relative 16S rRNA gene. Sulfonamide concentrations ranged from 120 ng/L, while tetracyclines 50–160 ng/L. Notably, sulfamethazine decreased significantly two (Shanhu Zhaoqiao, p < 0.05), other showed minimal variation, indicating persistent contamination agricultural runoff wastewater discharge. lower than September, being cumulatively genes. Strong correlations (r > 0.7) observed parameters like dissolved oxygen pH. High levels areas without nearby hospitals or pharmaceutical companies, implicating agriculture as major pollution source. By analyzing across eutrophic China, we highlight drivers proliferation propose targeted mitigation strategies.
Language: Английский
Citations
1
Environmental Pollution, Journal Year: 2024, Volume and Issue: 362, P. 125018 - 125018
Published: Sept. 23, 2024
Language: Английский
Citations
4
Environmental Monitoring and Assessment, Journal Year: 2025, Volume and Issue: 197(5)
Published: April 24, 2025
Language: Английский
Citations
0
Frontiers in Microbiology, Journal Year: 2025, Volume and Issue: 16
Published: May 19, 2025
Antibiotic resistance genes (ARGs) and antibiotic-resistant bacteria (ARB) have attracted more attentions in fermented feed recently. However, little information is available on the occurrence distribution of ARGs ensiled forages alpine region Qinghai-Tibetan plateau (QTP) with an extremely harsh environment. The study investigated spread mechanism ARB Elymus nutans silage along 2600 m (low), 3600 (medium) 4600 (high) altitude QTP. major ARG types were multidrug, aminoglycoside, bacitracin, beta-lactam polymyxin, while tnpA IS91 dominant mobile genetic elements (MGEs) subtypes silage. mainly carried by Pantoea, Enterobacter, Serratia, Lelliottia. Although altitudinal gradient had no influence diversity or abundance other MGEs (p > 0.05), network co-occurrence patterns among ARGs, MGEs, high-altitude complex than that low- medium-altitude silages. clinical bacA acrF, decreased prolonged fermentation time. This provides important data status forage from
Language: Английский
Citations
0
Current Opinion in Infectious Diseases, Journal Year: 2025, Volume and Issue: unknown
Published: June 5, 2025
Purpose of review This examines the interplay between biological and anthropogenic factors in development persistence antimicrobial resistance (AMR) within building plumbing systems, which is particular concern high risk setting such as healthcare facilities. The highlights role biofilms amoeba reservoirs for AMR explores how engineering design decisions, governance structures, cleaning protocols influence microbial dynamics. Recent findings Biofilms provide a protective environment that facilitates horizontal gene transfer enhances bacterial to disinfection. Amoeba-hosted bacteria can evade standard practices, further promoting persistence. Emerging technologies, digital twin modelling, offer new opportunities optimize mitigation strategies. However, more consideration needed be given or management decision may have unintended consequences, outcomes, increased biofilm growth from tap mixers low-flow fixtures, ineffective protocols, inadvertently worsen AMR. Summary Effectively managing systems requires multidisciplinary approach integrates microbiology, engineering, policy. Data driven assessments identify high-risk areas require changes but also enable targeted strategies, reducing reliance on widespread disinfection drive resistance. Future policies must consider system-wide implications prevent consequences. By addressing both drivers, we develop sustainable solutions mitigate risks beyond.
Language: Английский
Citations
0
Journal of Cleaner Production, Journal Year: 2024, Volume and Issue: unknown, P. 144495 - 144495
Published: Dec. 1, 2024
Language: Английский
Citations
1
Environmental Research, Journal Year: 2024, Volume and Issue: 263, P. 120051 - 120051
Published: Sept. 23, 2024
Language: Английский
Citations
0