Engineering the phycosphere: fundamental concepts and tools for the bottom-up design of microalgal-bacterial consortia DOI Creative Commons

Austin Semple,

Jagroop Pandhal

Applied Phycology, Journal Year: 2024, Volume and Issue: 6(1), P. 21 - 51

Published: Dec. 23, 2024

Microalgae are a promising platform for the sustainable production of high-value compounds, while also serving as robust degraders toxic pollutants that accumulate in industrial waste streams. As synthetic biologists continue to optimize microalgae so they can compete with conventional microbial hosts, major limitation is compromised central metabolism, following transformation heterologous pathways interfere distribution cellular resources. The co-cultivation microorganisms, including bacteria, has emerged branch biology, rationale distributing metabolic burden inflicted by degradation and synthesis processes aid alleviating stress, polycultures reduce susceptibility contamination. Furthermore, bacteria have co-evolved share resources many aquatic ecosystems, playing pivotal role nutrient cycling. Recent studies these symbioses revealed exchange diverse growth-promoting probiotics, ranging from vitamins metals act co-substrates, amino acids small metabolite infochemicals which dictate population-level shifts phenotype. interface interactions termed phycosphere, dynamic hotspot symbiotic relationships, transient nature, highlighting difficulty establishing stable consortia fit use. Therefore, development interaction screens assays identifying strains optimizing culture conditions important suited desired functions. Equally application meta-omics tools decipher functional interactions, revealing targets improving functionality stability. Here, we review current understanding microalgal microbiome, well bottom-up alga-bacteria co-culture design. We finish perspectives on potential engineering phycosphere applications, where there an increasing need methods manufacturing using adopting circular economy.

Language: Английский

Algae- and bacteria-based biodegradation of phthalic acid esters towards the sustainable green solution DOI
Veghar Amirian, Mohammad Russel, Zetty Norhana Balia Yusof

et al.

World Journal of Microbiology and Biotechnology, Journal Year: 2025, Volume and Issue: 41(2)

Published: Jan. 7, 2025

Language: Английский

Citations

3

The aging and pollution behavior of microplastics in tap water supply system subjected to residual chlorine exposure DOI
Pengxiao Liu, Shuai Gao, Ying Li

et al.

Environmental Science and Pollution Research, Journal Year: 2025, Volume and Issue: unknown

Published: March 18, 2025

Language: Английский

Citations

0

Spatial heterogeneity of EPS-mediated microplastic aggregation in phycosphere shapes polymer-specific Trojan horse effects DOI

Xuan Fan,

Chen Wang,

Lingyu Kong

et al.

Water Research, Journal Year: 2025, Volume and Issue: unknown, P. 123686 - 123686

Published: April 1, 2025

Language: Английский

Citations

0

Engineering the phycosphere: fundamental concepts and tools for the bottom-up design of microalgal-bacterial consortia DOI Creative Commons

Austin Semple,

Jagroop Pandhal

Applied Phycology, Journal Year: 2024, Volume and Issue: 6(1), P. 21 - 51

Published: Dec. 23, 2024

Microalgae are a promising platform for the sustainable production of high-value compounds, while also serving as robust degraders toxic pollutants that accumulate in industrial waste streams. As synthetic biologists continue to optimize microalgae so they can compete with conventional microbial hosts, major limitation is compromised central metabolism, following transformation heterologous pathways interfere distribution cellular resources. The co-cultivation microorganisms, including bacteria, has emerged branch biology, rationale distributing metabolic burden inflicted by degradation and synthesis processes aid alleviating stress, polycultures reduce susceptibility contamination. Furthermore, bacteria have co-evolved share resources many aquatic ecosystems, playing pivotal role nutrient cycling. Recent studies these symbioses revealed exchange diverse growth-promoting probiotics, ranging from vitamins metals act co-substrates, amino acids small metabolite infochemicals which dictate population-level shifts phenotype. interface interactions termed phycosphere, dynamic hotspot symbiotic relationships, transient nature, highlighting difficulty establishing stable consortia fit use. Therefore, development interaction screens assays identifying strains optimizing culture conditions important suited desired functions. Equally application meta-omics tools decipher functional interactions, revealing targets improving functionality stability. Here, we review current understanding microalgal microbiome, well bottom-up alga-bacteria co-culture design. We finish perspectives on potential engineering phycosphere applications, where there an increasing need methods manufacturing using adopting circular economy.

Language: Английский

Citations

0