Exposure to MC-LR activates the RAF/ERK signaling pathway, leading to renal inflammation and tissue damage in mice DOI
Yiwen Hou, Ying Liu, Yue Yang

et al.

Journal of Toxicology and Environmental Health, Journal Year: 2024, Volume and Issue: unknown, P. 1 - 9

Published: Dec. 23, 2024

Exposure to microcysatin-LR (MC-LR) is known result in kidney damage, however the underlying mechanisms involved MC-LR-initiated renal injury are not known. Thus, aim of this study was examine effects exposure MC-LR on human embryo (HEK 293) cell

Language: Английский

Cyanotoxin: A Potential Driver of Microbial Community DOI
Uzma Batool, Linda A. Lawton, B. Jesse Shapiro

et al.

Published: Jan. 1, 2025

Cyanobacterial algal blooms (CyanoHABs) are common biological disturbances in freshwater ecosystems that affect microbial community diversity and composition. While extensive research has focused on cyanobacterial blooms, the direct effects of cyanotoxins communities remain less understood. In this study, we investigated impact various an oligotrophic system Quebec, Canada (45.99°N, 74.00°W). Water samples were exposed to different concentrations MC-LR, MC-RR, MC-LF, CYN, both individually combination. Toxin chosen relation World Health Organization (WHO) regulatory thresholds, 1 μg/L as indicative low toxin exposure (drinking water limit) 1000 high (lake threshold). We performed a longitudinal analysis 16S rRNA assess changes composition at 24-hour, 48-hour, 72-hour intervals. Our findings showed significant change alpha beta diversity, highlighting shifts structure response cyanotoxin doses. Conversely, no detected across diverse compositions. then differential identified several ASVs with relative abundance This highlighted potential degrading bacteria, such Paucibacter, Flavobacterium, Ideonella. Overall, our results more associated doses than Understanding how could lakes is essential for better predicting their ecological impacts, especially these increasingly affected by blooms.

Language: Английский

Citations

0
Effects of extracellular organic matter from bacteria on the growth, physiology, photosynthesis, and transcriptome of the bloom-forming algal species DOI

Jiao Ran,

Rong Xiang,

Binghui Zheng

et al.

Journal of Hazardous Materials, Journal Year: 2025, Volume and Issue: 489, P. 137558 - 137558

Published: Feb. 10, 2025

Language: Английский

Citations

0
Short-term effects and mechanisms of micro/nanoplastics on the degradation of microcystin-LR by Sphingopyxis sp. YF1 DOI
Tangjian Peng, Yanqing Tang,

Shengyu Zhang

et al.

Journal of environmental chemical engineering, Journal Year: 2025, Volume and Issue: unknown, P. 116422 - 116422

Published: March 1, 2025

Language: Английский

Citations

0
Exposure to MC-LR activates the RAF/ERK signaling pathway, leading to renal inflammation and tissue damage in mice DOI
Yiwen Hou, Ying Liu, Yue Yang

et al.

Journal of Toxicology and Environmental Health, Journal Year: 2024, Volume and Issue: unknown, P. 1 - 9

Published: Dec. 23, 2024

Exposure to microcysatin-LR (MC-LR) is known result in kidney damage, however the underlying mechanisms involved MC-LR-initiated renal injury are not known. Thus, aim of this study was examine effects exposure MC-LR on human embryo (HEK 293) cell

Language: Английский

Citations

0