HPA flexibility and FKBP5: promising physiological targets for conservation DOI Creative Commons
Cédric Zimmer, Blanca Jimeno, Lynn B. Martin

et al.

Published: Nov. 30, 2023

Hypothalamic-pituitary-adrenal axis (HPA) flexibility is an emerging concept recognizing that individuals will cope best with stressors probably be those using their hormones in the most adaptive way. The HPA considers glucocorticoids as molecules convey information about environment from brain to body so organismal phenotype comes complement prevailing conditions. In this context, FKBP5 protein appears set extent which circulating glucocorticoid concentrations can vary within and across stressors. Thus, expression, it causes, seem represent individual’s ability regulate its orchestrate responses As expression also easily measured blood, could a worthy target of conservation-oriented research attention. We first review known likely roles wildlife. then describe putative genetic, environmental, epigenetic causes variation among- within-individuals. Finally, we hypothesize how should affect fitness hence population viability response human-induced rapid environmental changes, particularly urbanization.

Language: Английский

Unpredictability of maternal environment shapes offspring behaviour without affecting stress-induced cortisol in an annual vertebrate DOI Creative Commons
Agnieszka Magierecka, B. D. Cooper, Katherine A. Sloman

et al.

Hormones and Behavior, Journal Year: 2023, Volume and Issue: 154, P. 105396 - 105396

Published: July 1, 2023

Exposure of females to stressful conditions during pregnancy or oogenesis has a profound effect on the phenotype their offspring. For example, offspring behavioural may show altered patterns in terms consistency and average level performance. Maternal stress can also affect development axis leading alterations physiological response. However, majority evidence comes from studies utilising acute stressors exogenous glucocorticoids, little is known about chronic maternal stress, particularly context lasting throughout entire reproductive lifespan. To bridge this knowledge gap, we exposed female sticklebacks unpredictable environmental breeding season. We quantified activity, sheltering anxiety-like behaviour three successive clutches these females, calculated Intra-class Correlation Coefficients for behaviours siblings half-siblings. an stressor measured peak cortisol levels. An environment had no modifying inter-clutch responsivity, but resulted diversification behaviour, indicated by increased between-individual variability within families. This represent bet-hedging strategy, whereby produce differing phenotype, increase chance that some will be better at coping with anticipated conditions.

Language: Английский

Citations

1
Glucocorticoids, environmental challenges, and reproduction in birds DOI
Sharon E. Lynn, Z Morgan Benowitz‐Fredericks

Elsevier eBooks, Journal Year: 2024, Volume and Issue: unknown, P. 139 - 173

Published: Jan. 1, 2024

Language: Английский

Citations

0
Profiling mRNA encoding glucocorticoid receptor α in saliva: Relationship to hair cortisol levels in individuals aged 15-25 years DOI Creative Commons

Naima Abouseta,

Noha Gomaa, Ali Tassi

et al.

Archives of Oral Biology, Journal Year: 2024, Volume and Issue: 171, P. 106158 - 106158

Published: Dec. 4, 2024

Language: Английский

Citations

0
Evolutionary behavioral endocrinology: Introduction to the special issue DOI Open Access
Maren N. Vitousek, Ben Dantzer, Matthew J. Fuxjager

et al.

Hormones and Behavior, Journal Year: 2023, Volume and Issue: 152, P. 105356 - 105356

Published: April 7, 2023

Language: Английский

Citations

0
HPA flexibility and FKBP5: promising physiological targets for conservation DOI Creative Commons
Cédric Zimmer, Blanca Jimeno, Lynn B. Martin

et al.

Published: Nov. 30, 2023

Hypothalamic-pituitary-adrenal axis (HPA) flexibility is an emerging concept recognizing that individuals will cope best with stressors probably be those using their hormones in the most adaptive way. The HPA considers glucocorticoids as molecules convey information about environment from brain to body so organismal phenotype comes complement prevailing conditions. In this context, FKBP5 protein appears set extent which circulating glucocorticoid concentrations can vary within and across stressors. Thus, expression, it causes, seem represent individual’s ability regulate its orchestrate responses As expression also easily measured blood, could a worthy target of conservation-oriented research attention. We first review known likely roles wildlife. then describe putative genetic, environmental, epigenetic causes variation among- within-individuals. Finally, we hypothesize how should affect fitness hence population viability response human-induced rapid environmental changes, particularly urbanization.

Language: Английский

Citations

0