Production of ectoine by Vreelandella boliviensis using non-aseptic repeated-batch and continuous cultivations in an air-lift bioreactor DOI
Jeanett Daga-Quisbert, Daniela Mendieta,

Gunaratna Kuttuva Rajarao

et al.

International Microbiology, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 26, 2024

Language: Английский

Microbial Production of Ectoine: A Review DOI
Ke Wang,

Boya Cui,

Yi Wang

et al.

ACS Synthetic Biology, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 20, 2025

Ectoine is an important natural secondary metabolite widely used in biomedical fields, novel cosmetics development, and the food industry. Due to increasing market demand for ectoine, more cost-effective production methods are being explored. With rapid development of synthetic biology metabolic engineering technologies, ectoine using traditional halophilic bacteria gradually replaced by higher-yielding environmentally friendly nonhalophilic engineered strains. By introducing synthesis pathway into model strains optimizing fermentation process through various regulations, high-level can be achieved. This review focuses on strategies microbial including screening wild strains, mutation breeding, elucidate current research status provide insights industrial ectoine.

Language: Английский

Citations

1
Polyextremophile engineering: a review of organisms that push the limits of life DOI Creative Commons
Joaquín Caro‐Astorga, Joseph T. Meyerowitz, Devon A. Stork

et al.

Frontiers in Microbiology, Journal Year: 2024, Volume and Issue: 15

Published: June 5, 2024

Nature exhibits an enormous diversity of organisms that thrive in extreme environments. From snow algae reproduce at sub-zero temperatures to radiotrophic fungi nuclear radiation Chernobyl, raise many questions about the limits life. Is there any environment where life could not “find a way”? Although individual extremophilic have been identified and studied, remain outstanding extent which properties can be enhanced, combined or transferred new organisms. In this review, we compile current knowledge on bioengineering extremophile microbes. We summarize what is known basic mechanisms adaptations, synthetic biology’s efforts engineer beyond found nature, highlight adaptations combined. The science extremophiles applied engineered tailored specific biomanufacturing needs, such as growth high presence unusual solvents.

Language: Английский

Citations

5
Comparing three emerging industrial cell factories: Pseudomonas putida KT2440, Halomonas bluephagenesis TD01, and Zymomonas mobilis ZM4 DOI
Yuhang Zhang,

Chunyan Xue,

Bingqiu Chen

et al.

Current Opinion in Biotechnology, Journal Year: 2025, Volume and Issue: 92, P. 103255 - 103255

Published: Jan. 20, 2025

Language: Английский

Citations

0
Identification of key chromium resistance genes in Cellulomonas using transcriptomics DOI Creative Commons

Hongmei Sun,

Yongdong Li,

Shengchao Gao

et al.

Ecotoxicology and Environmental Safety, Journal Year: 2025, Volume and Issue: 291, P. 117843 - 117843

Published: Feb. 1, 2025

Language: Английский

Citations

0
Ektoin: Mikrobiyal Hayatta Kalma Sırrından Biyoteknolojik Uygulamalara DOI
Mustafa Çiçek, Esra Çiçek, Aytaç Kocabaş

et al.

Iğdır Üniversitesi Fen Bilimleri Enstitüsü Dergisi, Journal Year: 2025, Volume and Issue: 15(1), P. 92 - 109

Published: Feb. 19, 2025

Fizyolojik ve taksonomik açıdan oldukça büyük çeşitlilik sergileyen mikroorganizma türleri tarafından yüksek tuzluluk veya aşırı sıcaklık gibi çevresel stres faktörlerine yanıt olarak üretilen uyumlu çözünenlerden olan ektoin, özellikle mikrobiyoloji, biyoteknoloji çevre bilimi alanlarında ilgi gören doğal bir bileşiktir. Olumsuz koşullar altında hücresel bütünlüğün işlevselliğin korunması açısından kritik molekül ektoinin sentezinin arkasında yatan mekanizmaların aydınlatılmasına adaptasyonundaki rollerinin tanımlanmasına yönelik pek çok çalışma gerçekleştirilmiştir. Sergilediği olağanüstü biyoteknolojik potansiyele bağlı araştırmacıların dikkatini çeken ektoin başta kozmetik ilaç endüstrileri olmak üzere çeşitli sektörlerde yaygın kullanım alanı bulmaktadır. Bu durum yandan üretim potansiyeline sahip yeni türlerin keşfedilmesine çalışmalara hız kazandırırken da mikrobiyal kaynaklardan; uygun maliyetli sürdürülebilir yöntemlerle ölçekli stratejilerinin geliştirilmesini teşvik etmektedir. inceleme, mevcut uygulama alanlarına kapsamlı genel bakış sunarak endüstrilerde gelişen rolünü vurgulamakta ektoini geniş etkilere yönlü etkili bileşik konumlandırmaktadır.

Citations

0
Production of polyhydroxybutyrate from wheat straw hydrolysate using a low-salt requiring and alkaliphilic Halomonas nigrificans X339 under non-sterile open condition DOI Creative Commons
Tong Xu, Hao Li, Shengjie Zhang

et al.

Bioresource Technology, Journal Year: 2025, Volume and Issue: unknown, P. 132276 - 132276

Published: Feb. 1, 2025

Language: Английский

Citations

0
Next-generation biotechnology inspired by extremes DOI Creative Commons

Shuang Zheng,

Mingwei Shao,

Wanze Wang

et al.

EMBO Reports, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 27, 2025

Language: Английский

Citations

0
The Halo of Future Bio-industry based on Engineering Halomonas DOI

Xu Yan,

Jiale Wang,

Rou Wen

et al.

Metabolic Engineering, Journal Year: 2025, Volume and Issue: unknown

Published: March 1, 2025

Language: Английский

Citations

0
Multi-gene metabolic engineering of Pichia pastoris to synthesize ectoine DOI
Shuai Zhang, Bingjie Cheng, Qing Liao

et al.

Journal of Bioscience and Bioengineering, Journal Year: 2025, Volume and Issue: unknown

Published: March 1, 2025

Language: Английский

Citations

0
The tropical marine actinomycete Nocardiopsis dassonvillei NCIM 5124 as novel source of ectoine: Genomic and transcriptomic insights DOI

Pratik Kadam,

Vitthal T. Barvkar, Ashwini M. Darshetkar

et al.

Gene, Journal Year: 2024, Volume and Issue: 930, P. 148860 - 148860

Published: Aug. 14, 2024

Language: Английский

Citations

3