Parental Awareness and Practices of Self-medication with Antibiotics among Hospitalised Children in Pakistan: Findings and Implications from a Cross-sectional Study DOI Creative Commons
Zia Ul Mustafa, Amer Hayat Khan,

Muhammad Salman

et al.

Advances in Human Biology, Journal Year: 2025, Volume and Issue: unknown

Published: March 29, 2025

Abstract Introduction: Antimicrobial resistance (AMR) is a global threat appreciably impacting on morbidity, mortality and costs, especially in low- middle-income countries. The excessive use of antibiotics, ambulatory care, primary factor increasing AMR. This includes inappropriate dispensing antibiotics without prescription for essentially viral infections, which prevalent Pakistan. needs addressing to reduce Materials Methods: A cross-sectional study was conducted among three district hospitals extract data from parents children up 12 years concerning their awareness, practices rationale self-medication with children. Results: Four hundred thirty-eight participated the study, majority between 30 39 (65.5%) possessing secondary school education (28.5%). 27.6% stated that they knew name at least one antibiotic, knowing amoxicillin (33%) co-amoxiclav (19%). prevalence high 63%, principally self-limiting conditions including sore throats (27.1%), fever (22.4%), nasal discharges (20.9%) coughs (17.7%). most commonly consumed were (33.6%), (18.1%) azithromycin (15.2%), common reasons similar signs symptoms before (42.6%) financial constraints (39%). Increasing levels familiarity antibiotic names associated higher usage ( P < 0.001). Conclusions: Self-medication common. Appropriate corrective measures, targeted educational initiatives, are urgently need address ongoing concerns rising

Language: Английский

‘When global health meets global goals’: assessing the alignment between antimicrobial resistance and sustainable development policies in 10 African and Asian countries DOI Creative Commons
Luong Nguyen-Thanh, Didier Wernli, Mats Målqvist

et al.

BMJ Global Health, Journal Year: 2025, Volume and Issue: 10(3), P. e017837 - e017837

Published: March 1, 2025

Background Sustainable development goals (SDGs) may play a pivotal role in mitigating antimicrobial resistance (AMR). This study examines how countries can integrate AMR mitigation with sustainable strategies, providing evidence on the prioritisation of AMR-related efforts within both agendas. Methods We conducted comparative analysis international global action plan (GAP) and national (NAP) SDGs across 10 Africa Asia. employed content to map actions drivers, descriptive statistics summarise coverage focus inferential explore factors associated level policy alignment. Results Our findings highlight gaps current landscape, where drivers are at risk being redundantly addressed, narrowly focused or entirely overlooked. At level, over 50% addressed by frameworks, but national-level overlap is lower (10.5%–47.4%), Asian showing stronger alignment than African countries. show higher proportion shared A considerable solely AMR-NAPs (23.7%–60.5%) SDG-NAPs (13.2%–31.6%), raising concerns that benefit either expense other. Finally, 10.5%–26.3% mostly distal, not acknowledged framework, highlighting potential blind spots. Conclusions The Agenda 2030 includes ambitious cross-cutting GAP-AMR, therefore it facilitate intersectoral collaboration addressing AMR. effective implementation agendas will depend governments’ capacity ensure combating also contribute development.

Language: Английский

Citations

0

Increasing the use of the WHO AWaRe system in antibiotic surveillance and stewardship programmes in low- and middle-income countries DOI Creative Commons
Zikria Saleem,

Samia Sheikh,

Brian Godman

et al.

JAC-Antimicrobial Resistance, Journal Year: 2025, Volume and Issue: 7(2)

Published: March 4, 2025

Antimicrobial resistance (AMR) presents a major global health threat, driven in part by the inappropriate use of antibiotics including low- and middle-income countries (LMICs). Improving quality antibiotic is key rationale for development WHO's AWaRe (Access, Watch Reserve) system. There need to review uptake system since its launch guide future practice. A literature search was conducted between 2017, AWaRe, 2024. Inclusion criteria were studies that reported on LMICs using Eighty-five included review, which 56.4% focused trends, with 28.2% reporting prescribing patterns; 51.7% inpatients. Only 14.1% meeting 2024 United Nations General Assembly (UNGA) AMR recommended target at least 70% human being Access antibiotics, concerning trend overuse (68.2% studies). Dispensing practices revealed significant dispensing without prescriptions especially Pakistan Bangladesh. more available but also expensive than antibiotics. Encouragingly, many are now via system, antimicrobial stewardship programmes (ASPs). Wide variation exists proportion used across LMICs, an urgent targeted AWaRe-based ASPs meet recent UNGA recommendations. use, availability affordability essential combat AMR.

Language: Английский

Citations

0

Current access, availability and use of antibiotics in primary care among key low- and middle-income countries and the policy implications DOI Creative Commons
Zikria Saleem, Biset Asrade Mekonnen,

E Sam Orubu

et al.

Expert Review of Anti-infective Therapy, Journal Year: 2025, Volume and Issue: unknown

Published: March 20, 2025

Introduction Antimicrobial resistance (AMR) poses a significant threat, particularly in low- and middle-income countries (LMICs), exacerbated by inappropriate antibiotic use, access to quality antibiotics weak antimicrobial stewardship (AMS). There is need review current evidence on access, AMR, primary care across key countries.Areas covered: This narrative analyses publications from 2018 2024 regarding availability use of appropriate antibiotics.

Language: Английский

Citations

0

Global health perspectives on antibacterial drug discovery and the preclinical pipeline DOI
Ursula Theuretzbacher,

Ravindra P. Jumde,

Alan J. Hennessy

et al.

Nature Reviews Microbiology, Journal Year: 2025, Volume and Issue: unknown

Published: March 27, 2025

Language: Английский

Citations

0

Parental Awareness and Practices of Self-medication with Antibiotics among Hospitalised Children in Pakistan: Findings and Implications from a Cross-sectional Study DOI Creative Commons
Zia Ul Mustafa, Amer Hayat Khan,

Muhammad Salman

et al.

Advances in Human Biology, Journal Year: 2025, Volume and Issue: unknown

Published: March 29, 2025

Abstract Introduction: Antimicrobial resistance (AMR) is a global threat appreciably impacting on morbidity, mortality and costs, especially in low- middle-income countries. The excessive use of antibiotics, ambulatory care, primary factor increasing AMR. This includes inappropriate dispensing antibiotics without prescription for essentially viral infections, which prevalent Pakistan. needs addressing to reduce Materials Methods: A cross-sectional study was conducted among three district hospitals extract data from parents children up 12 years concerning their awareness, practices rationale self-medication with children. Results: Four hundred thirty-eight participated the study, majority between 30 39 (65.5%) possessing secondary school education (28.5%). 27.6% stated that they knew name at least one antibiotic, knowing amoxicillin (33%) co-amoxiclav (19%). prevalence high 63%, principally self-limiting conditions including sore throats (27.1%), fever (22.4%), nasal discharges (20.9%) coughs (17.7%). most commonly consumed were (33.6%), (18.1%) azithromycin (15.2%), common reasons similar signs symptoms before (42.6%) financial constraints (39%). Increasing levels familiarity antibiotic names associated higher usage ( P < 0.001). Conclusions: Self-medication common. Appropriate corrective measures, targeted educational initiatives, are urgently need address ongoing concerns rising

Language: Английский

Citations

0