Prenatal THC exposure produces a hyperdopaminergic phenotype rescued by pregnenolone DOI
Roberto Frau, Vivien Miczán, Francesco Traccis

et al.

Nature Neuroscience, Journal Year: 2019, Volume and Issue: 22(12), P. 1975 - 1985

Published: Oct. 14, 2019

Language: Английский

Public health monitoring of cannabis use in Europe: prevalence of use, cannabis potency, and treatment rates DOI Creative Commons
Jakob Manthey, Tom P. Freeman, Carolin Kilian

et al.

The Lancet Regional Health - Europe, Journal Year: 2021, Volume and Issue: 10, P. 100227 - 100227

Published: Sept. 24, 2021

Cannabis is one of the most widely used substances worldwide. Heavy use associated with an increased risk cannabis disorders, psychotic acute cognitive impairment, traffic injuries, respiratory problems, worse pregnancy outcomes, and there are indications for genotoxic epigenotoxic adverse effects. International regulation medical non-medical changing rapidly substantially, highlighting importance robust public health monitoring. This study aimed to describe trends key indicators in European Union (27 member states + UK, Norway Turkey) period 2010 2019, their implications, identify steps required improve current practice monitoring harm Europe.Data on four (prevalence use, prevalence disorder [CUD], treatment rates, potency products) Europe were extracted from United Nations Office Drugs Crime, Monitoring Centre Drug Addiction Global Burden Disease study. For CUD, first last available estimate each country compared. rates potency, linear regression models conducted.Between past-month by 27% adults (from 3·1 3·9%), pronounced relative increases observed among 35-64 year-olds. In 13 out 26 countries, over 20% all users reported high-risk patterns. The rate entry problems per 100,000 27·0 (95% CI: 17·2 36·8) 35·1 23·6 46·7) has mostly plateaued since 2015. Modest found herbal 6·9% 10·6% THC) while median THC values tripled resin 7·6% 24·1% THC).In past decade, levels have major concerns about impact use. Continued efforts data quality reporting, including cannabis-attributable harm, will be necessary evaluate international changes regulation.This received no specific funding.

Language: Английский

Citations

129
The schizophrenia syndrome, circa 2024: What we know and how that informs its nature DOI Open Access

Rajiv Tandon,

Henry A. Nasrallah, Schahram Akbarian

et al.

Schizophrenia Research, Journal Year: 2023, Volume and Issue: 264, P. 1 - 28

Published: Dec. 12, 2023

Language: Английский

Citations

64
THC and CBD: Similarities and differences between siblings DOI Creative Commons
Nephi Stella

Neuron, Journal Year: 2023, Volume and Issue: 111(3), P. 302 - 327

Published: Jan. 12, 2023

Citations

61
Cannabidiol (CBD) use in psychiatric disorders: A systematic review DOI

Stefania Bonaccorso,

A Ricciardi,

Caroline Zangani

et al.

NeuroToxicology, Journal Year: 2019, Volume and Issue: 74, P. 282 - 298

Published: Aug. 11, 2019

Language: Английский

Citations

142
Prenatal THC exposure produces a hyperdopaminergic phenotype rescued by pregnenolone DOI
Roberto Frau, Vivien Miczán, Francesco Traccis

et al.

Nature Neuroscience, Journal Year: 2019, Volume and Issue: 22(12), P. 1975 - 1985

Published: Oct. 14, 2019

Language: Английский

Citations

124