Review: Environmental toxicology of marine microplastic pollution — R0/PR2 DOI Creative Commons
Wen‐Xiong Wang

Published: Feb. 21, 2023

Over the past decade, there have been increasing recognition and concern of toxicological impacts microplastics (MPs) in environment, which widely found various marine environments from estuary to deep oceans. Numerous studies conducted on MPs organisms, especially phytoplankton, zooplankton, bivalves, fish different trophic levels. These mainly focused measurements bioaccumulation their resulting biological at molecular, metabolic, biochemical, physiological, organismic This review examines over recent years toxicology particularly toxicity MPs. The organisms are diverse, complexity organism physiology as well physical chemical properties need be considered. Future should consider environmental relevance research development quantitative tools model transport, bioaccumulation, important for real risk assessments environments.

Language: Английский

Microplastics and nanoplastics induced differential respiratory damages in tilapia fish Oreochromis niloticus DOI
Siwen Zheng, Ben Zhong Tang, Wen‐Xiong Wang

et al.

Journal of Hazardous Materials, Journal Year: 2023, Volume and Issue: 465, P. 133181 - 133181

Published: Dec. 6, 2023

Language: Английский

Citations

26
Microplastic ingestion in mussels from the East Mediterranean Sea: Exploring its impacts in nature and controlled conditions DOI

Νικολέττα Δίγκα,

Danae Patsiou,

Yannis Hatzonikolakis

et al.

The Science of The Total Environment, Journal Year: 2024, Volume and Issue: 946, P. 174268 - 174268

Published: June 24, 2024

Language: Английский

Citations

10
In silico analysis of novel triacontafluoropentadec-1-ene as a sustainable replacement for dodecane in fisheries microplastics: molecular docking, dynamics simulation and pharmacophore studies of acetylcholinesterase activity DOI

Rahul Thakur,

V. Joshi,

Ganesh Chandra Sahoo

et al.

Computational Biology and Chemistry, Journal Year: 2025, Volume and Issue: 115, P. 108358 - 108358

Published: Jan. 18, 2025

Language: Английский

Citations

1
Near-Infrared-II In Vivo Visualization and Quantitative Tracking of Micro/Nanoplastics in Fish DOI
Lanpeng Yang, Ben Zhong Tang, Wen‐Xiong Wang

et al.

ACS Nano, Journal Year: 2023, Volume and Issue: 17(19), P. 19410 - 19420

Published: Oct. 2, 2023

As emerging contaminants, micro/nanoplastics (MNPs) are widely present in aquatic environments and often ingested by organisms. However, the vivo trafficking fate of MNPs remain largely unknown. Here, we developed near-infrared (NIR) aggregated-induced emission (AIE) fluorophore-labeled microplastics (2 μm) nanoplastics (100 nm) as models MNPs. This model was based on NIR-AIE technique with strong at second (NIR-IIII) window, which overcomes interference autofluorescence observation artifacts detection commercial fluorescent-labeled particles. Due to its deep tissue penetration noninvasiveness, dynamic process accumulation transport individuals can be tracked NIR imaging. We then directly visualized quantified uptake depuration processes MPs NPs zebrafish. The results showed that were mainly accumulated fish gut, distribution heterogeneous. tended accumulate more fore mid areas gut compared NPs. Besides, both could large quantities locally might cause intestinal obstruction. slowly during initial exposure followed rapid sustained gut. Based these kinetic depuration, a refined toxicokinetic (TK) describe changes Overall, this study proposed MNP technique, provided reliable tracer technology for visualization, tracking quantification vivo.

Language: Английский

Citations

19
Investigating the behavioral implications of microplastic exposure in animal species DOI Open Access
Amir Hossein Hamidian,

Meisam Feizi

Annals of Animal Science, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 26, 2025

Abstract Microplastics (MPs) are pervasive pollutants impacting ecosystems worldwide, causing physical harm and behavioral changes in wildlife. MP toxicity mainly depends on size, porosity, weathering, surrounding compounds. MPs disrupt feeding metabolism, resulting reproductive, neurological, disorders. These impacts significantly alter ecological niches reduce animal survival. Understanding these is crucial for assessing the broader effects of plastic pollution developing effective mitigation strategies. This review investigated 110 papers quantifying consequences while considering their_physiological basis, emphasizing significance their potential long-term influence populations ecosystems. study thoroughly investigates model species, including plankton, fish, amphibians, crustaceans, pollinators, mammals. Fish exhibited most significant impact, crustaceans showed least. Mice, representing mammals, displayed severe physiological damage.

Language: Английский

Citations

0
Polypropylene microplastic exposure modulates multiple metabolic pathways in tobacco leaves, impacting lignin biosynthesis DOI Creative Commons
Muhammad Arshad, Yuxuan Ma, Weichang Gao

et al.

Ecotoxicology and Environmental Safety, Journal Year: 2025, Volume and Issue: 292, P. 118005 - 118005

Published: March 1, 2025

The adverse effects of microplastics (MPs) and nanoplastics (NPs) on plant growth have gained significant attention. However, the response tobacco plants to polypropylene (PP-MPs) remains poorly understood. To address this, a microcosm experiment was conducted in which seedlings were exposed PP-MPs at varying concentrations (100 1000 mg/kg) particle sizes (20 nm 100 µm) for 48 days red soil. physicochemical, transcriptomic, metabolic responses PP-MP treatments assessed. Our findings indicate that effect exposure dose-dependent, with higher doses (1000 inducing significantly stronger responses. Further, accumulation key metabolites phenylpropanoid flavonoid biosynthesis pathways such as quercetin, phloretin, kaempferol, liquiritigenin, naringin, myricetin, ferulic acid, formaldehyde, methyl eugenol observed PP-MPs. Additionally, transcriptomic analysis revealed enriched more DEGs than lower. KEGG pathway identified enrichment biosynthesis, sesquiterpenoid triterpenoid hormone signal transduction. notable variation expression enzyme-related genes PAL, CHI, CSE, C4H, 4CL, COMT, CYP indicates substantial impact lignin synthesis. Lastly, large-sized PPMPs alter activity lignin-degrading enzymes, affecting content. This study offers valuable insights into PP-MPs, integrating both physicochemical molecular perspectives.

Language: Английский

Citations

0
Exposure to metoprolol and propranolol mixtures on biochemical, immunohistochemical, and molecular alterations in the American oyster, Crassostrea virginica DOI Creative Commons
A.S. Salinas Sánchez, Md Saydur Rahman

Toxicology Reports, Journal Year: 2025, Volume and Issue: 14, P. 101979 - 101979

Published: March 4, 2025

Pharmaceutical drugs, particularly beta-blockers (e.g., metoprolol, propranolol, etc.), are extensively used to treat human cardiovascular conditions, yet pose significant risks non-target aquatic organisms when introduced into coastal and marine environments via wastewater effluent. This study aimed investigate the effects of short-term exposure (one week) environmentally relevant concentrations metoprolol propranolol (MP) mixtures (low-dose: 50 ng/L 250 high-dose: 650 metoprolol) in American oyster (Crassostrea virginica, a commercially ecologically important bivalve mollusk) under controlled laboratory conditions. Histopathological assessments revealed structural damage gills, connective tissues, digestive glands both low- high-dose MP treatment groups. Additionally, glucose concentration pH extrapallial fluid significantly declined Hemocyte density tissues increased proportionally with dosages. reduced mucous secretion gills glands. Immunohistochemical results showed (P < 0.05) upregulation 3-nitrotyrosine protein (NTP, biomarker nitration) expression oysters exposed mixtures. Alongside, decreased acetylcholinesterase (AChE, cholinergic enzyme) tissues. Our findings suggest that induce nitration, leading altered tissue morphology, disrupting homeostasis, downregulating AChE may impair physiological functions oysters.

Language: Английский

Citations

0
Marine Micro(nano)plastics Toxicology: Knowledge Gaps and Perspectives DOI Creative Commons
Wen‐Xiong Wang

Journal of Hazardous Materials, Journal Year: 2025, Volume and Issue: unknown, P. 138086 - 138086

Published: March 1, 2025

Language: Английский

Citations

0
Toxic effects of emerging pollutants on mucosal organs of teleost fish: A review focusing on mucosal microbiota, physical barrier and immune barrier DOI
Jiaming Zhang, Ping Li,

Cheng-Zhuang Chen

et al.

The Science of The Total Environment, Journal Year: 2025, Volume and Issue: 978, P. 179431 - 179431

Published: April 16, 2025

Language: Английский

Citations

0
The dual role of coastal mangroves: Sinks and sources of microplastics in rapidly urbanizing areas DOI
Kun Qiao, Wen‐Xiong Wang

Journal of Hazardous Materials, Journal Year: 2024, Volume and Issue: 480, P. 136408 - 136408

Published: Nov. 4, 2024

Language: Английский

Citations

3