Enhancing task fMRI individual difference research with neural signatures
medRxiv (Cold Spring Harbor Laboratory),
Journal Year:
2025,
Volume and Issue:
unknown
Published: Jan. 31, 2025
Abstract
Task-based
functional
magnetic
resonance
imaging
(tb-fMRI)
has
advanced
our
understanding
of
brain-behavior
relationships.
Standard
tb-fMRI
analyses
suffer
from
limited
reliability
and
low
effect
sizes,
machine
learning
(ML)
approaches
often
require
thousands
subjects,
restricting
their
ability
to
inform
how
brain
function
may
arise
contribute
individual
differences.
Using
data
9,024
early
adolescents,
we
derived
a
classifier
(‘neural
signature’)
distinguishing
between
high
working
memory
loads
in
an
emotional
n-back
fMRI
task,
which
captures
differences
the
separability
activation
two
task
conditions.
Signature
predictions
were
more
reliable
had
stronger
associations
with
performance,
cognition,
psychopathology
than
standard
estimates
regional
activation.
Further,
signature
was
sensitive
required
smaller
training
sample
(N=320)
ML
approaches.
Neural
signatures
hold
tremendous
promise
for
enhancing
informativeness
research
revitalizing
its
use.
Language: Английский
Artificial intelligence for children with attention deficit/hyperactivity disorder: a scoping review
Experimental Biology and Medicine,
Journal Year:
2025,
Volume and Issue:
250
Published: April 24, 2025
Attention
deficit/hyperactivity
disorder
is
a
common
neuropsychiatric
that
affects
around
5%-7%
of
children
worldwide.
Artificial
intelligence
provides
advanced
models
and
algorithms
for
better
diagnosis,
prediction
classification
attention
disorder.
This
study
aims
to
explore
artificial
used
the
prediction,
early
diagnosis
as
reported
in
literature.
A
scoping
review
was
conducted
line
with
PRISMA-ScR
(Preferred
Reporting
Items
Systematic
Reviews
Meta-Analyses
Extension
Scoping
Reviews)
guidelines.
Out
1994
publications,
52
studies
were
included
review.
The
articles
use
3
different
purposes.
Of
these
articles,
techniques
mostly
(38/52,
79%).
Magnetic
resonance
imaging
(20/52,
38%)
most
frequently
data
articles.
Most
sets
size
<1,000
samples
(28/52,
54%).
Machine
learning
prominent
branch
studies,
support
vector
machine
algorithm
(34/52,
65%).
commonly
validation
k-fold
cross-validation
higher
level
accuracy
(98.23%)
found
Convolutional
Neural
Networks
algorithm.
an
overview
research
on
disorder,
providing
further
clinical
decision-making
healthcare.
Language: Английский