Clinical Profile, Comorbidities, and Outcome of the Unvaccinated and Hospitalized for COVID-19 in Northern Brazil: Retrospective Cohort DOI Open Access

Ana Lúcia Da Silva Ferreira,

Daniele Melo Sardinha,

Daiane Cristina Viana de Moraes

et al.

Archives of Current Research International, Journal Year: 2023, Volume and Issue: 23(7), P. 53 - 66

Published: Aug. 9, 2023

Introduction: Over the course of pandemic, COVID-19 affected health, economy and quality life in Brazil. The worst years for country were first second. There delays vaccine purchases political reasons at time. northern region had a higher mortality rate compared to other regions, associated with local vulnerabilities fragility surveillance due geographic population characteristics. Objective: To investigate clinical profile, comorbidities, outcome unvaccinated people hospitalized state Pará 2022. Methods: Retrospective cohort epidemiological study, data from national acute severe respiratory syndromes. Cases reported 2022 vaccinated yes or no field completed doses included. Only closed cases cure death We performed chi-square test on categorical variables Mann-Whitney numerical variables. VS non-vaccinated; we Odds Ratio significant used SPSS 20.0 software. Results: study worked 2,634 period, confirmed by RT-PCR (851/32.30%) (1,784/67.70%) rapid antigen test. lethality was (778/29.53%), those two (1,473/55.90%) dose (1,162/44.10%). Death represents p- <0.001 (HR 1.306 - CI 1.124/1.517) risk event occurring cases, followed male sex p-0.004 1.188 1.058/1.334). Conclusion: Brazil north evaluate patients this Amazon region, which is characterized vulnerability factors unique regions Brazil, showed that males, younger, fewer they deaths.

Language: Английский

SARS-CoV-2 seroprevalence in vaccine-naïve participants from the Democratic Republic of Congo, Guinea, Liberia, and Mali DOI Creative Commons
Sylvain Laverdure,

Donatien Kazadi,

Kadidia Kone

et al.

International Journal of Infectious Diseases, Journal Year: 2024, Volume and Issue: 142, P. 106985 - 106985

Published: Feb. 28, 2024

The InVITE study, starting in August 2021, was designed to examine the immunogenicity of different vaccine regimens several countries including Democratic Republic Congo, Guinea, Liberia, and Mali. Prevaccination baseline samples were used obtain estimates previous SARS-CoV-2 infection study population.

Language: Английский

Citations

1
Prevalence of anti-SARS-CoV-2 antibodies in people attending the two main Goma markets in the eastern Democratic Republic of the Congo DOI Creative Commons

Prudence Mitangala,

Léonid M. Irenge,

Edgar Tsongo Musubao

et al.

Epidemiology and Infection, Journal Year: 2023, Volume and Issue: 151

Published: Jan. 1, 2023

The Democratic Republic of the Congo (DRC) officially reports low coronavirus disease 19 (COVID-19) prevalence. This cross-sectional study, conducted between September and November 2021, assessed COVID-19 seroprevalence in people attending Goma's two largest markets, Kituku Virunga. A similar study a slum Bukavu overlapped for 1 month using identical methods. COVID-19-unvaccinated participants (n = 796 including 454 vendors 342 customers, 60% whom were women) surveyed. median age customers was 34.2 30.1 years, respectively. crude adjusted anti-SARS-CoV-2 antibody rates 70.2% (95% CI 66.9-73.4%) 98.8% 94.1-100%), respectively, with no difference customers. symptoms reported by survey previous 6 months mild or absent 58.9% 41.1% antibodies, No COVID-19-seropositive hospitalisation last months. These findings are consistent those Bukavu. They confirm that SARS-CoV-2 spread without causing severe densely populated settlements markets suggest many cases went unreported. Based on these results, relevance an untargeted hypothetical vaccination programme communities should be questioned.

Language: Английский

Citations

2
COVID-19 epidemiology, health services utilisation and health care seeking behaviour during the first year of the COVID-19 pandemic in Mweso health zone, Democratic Republic of Congo DOI Creative Commons
Chiara Altare, Natalya Kostandova,

Linda Matadi Basadia

et al.

Journal of Global Health, Journal Year: 2024, Volume and Issue: 14

Published: April 26, 2024

Although the evidence about coronavirus disease 2019 (COVID-19) has increased exponentially since beginning of pandemic, less is known direct and indirect effects pandemic in humanitarian settings. In Democratic Republic Congo (DRC), most studies occurred Kinshasa other cities. Limited research was conducted remote conflict-affected We investigated COVID-19 epidemiology, health service utilisation, care-seeking behaviour during first year (March 2020-March 2021) Mweso zone, North Kivu, DRC.

Language: Английский

Citations

0
Prevalence of anti-SARS-CoV-2 antibodies in people attending the two main Goma markets in the eastern Democratic Republic of Congo DOI Creative Commons

Mitangala Ndeba Prudence,

Léonid M. Irenge,

Musubao Tsongo Edgar

et al.

medRxiv (Cold Spring Harbor Laboratory), Journal Year: 2023, Volume and Issue: unknown

Published: Feb. 18, 2023

Abstract According to official data, the Democratic Republic of Congo (DRC) has a low prevalence coronavirus disease 19 (COVID-19) pandemic. The goal this cross-sectional study was determine COVID-19 seroprevalence in people attending Goma’s two largest markets, Kituku and Virunga. This conducted between September November 2021, overlapping by one month with another similar carried out slum Bukavu, using same methodology. unvaccinated participants (n = 796 including 454 vendors 342 customers, 60% whom were women) surveyed. median age customers 34.2 30.1 years, respectively. crude adjusted anti-SARS-CoV-2 antibody rates 70.2% (95 % CI 66.9-73.4%) 98.8% (95% 94.1-100%), respectively, no difference customers. symptoms mild or absent 58.9% 41.1% antibodies did not require hospitalisation for any seropositive participants. These findings are consistent those reported Bukavu. They confirm that SARS-CoV-2 spread without causing severe densely populated settlements suggest many cases went unreported. Based on these results, relevance an untargeted hypothetical vaccination programme communities should be questioned.

Language: Английский

Citations

0
Clinical Profile, Comorbidities, and Outcome of the Unvaccinated and Hospitalized for COVID-19 in Northern Brazil: Retrospective Cohort DOI Creative Commons
Ana Lúcia da Silva Ferreira, Daniele Melo Sardinha,

Daiane Cristina Viana de Moraes

et al.

medRxiv (Cold Spring Harbor Laboratory), Journal Year: 2023, Volume and Issue: unknown

Published: July 1, 2023

Abstract Over the course of pandemic, COVID-19 affected health, economy and quality life in Brazil. The worst years for country were first second. There delays vaccine purchases political reasons at time. northern region had a higher mortality rate compared to other regions, associated with local vulnerabilities fragility surveillance due geographic population characteristics. This study aims investigate clinical profile, comorbidities, outcome unvaccinated people hospitalized state Pará 2022. Retrospective cohort epidemiological study, data from national acute severe respiratory syndromes. Cases reported 2022 vaccinated yes or no field completed doses included. Only closed cases cure death We performed chi-square test on categorical variables Mann-Whitney numerical variables. VS non-vaccinated; we Odds Ratio significant used SPSS 20.0 software. worked 2,634 period, confirmed by RT-PCR (851/32.30%) (1,784/67.70%) rapid antigen test. lethality was (778/29.53%), those two (1,473/55.90%) dose (1,162/44.10%). Death represents p-<0.001 (HR 1.306 - CI 1.124/1.517) risk event occurring cases, followed male sex p-0.004 1.188 1.058/1.334).. Brazil north evaluate patients this Amazon region, which is characterized vulnerability factors unique regions Brazil, showed that males, younger, fewer they deaths.

Language: Английский

Citations

0
Clinical Profile, Comorbidities, and Outcome of the Unvaccinated and Hospitalized for COVID-19 in Northern Brazil: Retrospective Cohort DOI Open Access

Ana Lúcia Da Silva Ferreira,

Daniele Melo Sardinha,

Daiane Cristina Viana de Moraes

et al.

Archives of Current Research International, Journal Year: 2023, Volume and Issue: 23(7), P. 53 - 66

Published: Aug. 9, 2023

Introduction: Over the course of pandemic, COVID-19 affected health, economy and quality life in Brazil. The worst years for country were first second. There delays vaccine purchases political reasons at time. northern region had a higher mortality rate compared to other regions, associated with local vulnerabilities fragility surveillance due geographic population characteristics. Objective: To investigate clinical profile, comorbidities, outcome unvaccinated people hospitalized state Pará 2022. Methods: Retrospective cohort epidemiological study, data from national acute severe respiratory syndromes. Cases reported 2022 vaccinated yes or no field completed doses included. Only closed cases cure death We performed chi-square test on categorical variables Mann-Whitney numerical variables. VS non-vaccinated; we Odds Ratio significant used SPSS 20.0 software. Results: study worked 2,634 period, confirmed by RT-PCR (851/32.30%) (1,784/67.70%) rapid antigen test. lethality was (778/29.53%), those two (1,473/55.90%) dose (1,162/44.10%). Death represents p- <0.001 (HR 1.306 - CI 1.124/1.517) risk event occurring cases, followed male sex p-0.004 1.188 1.058/1.334). Conclusion: Brazil north evaluate patients this Amazon region, which is characterized vulnerability factors unique regions Brazil, showed that males, younger, fewer they deaths.

Language: Английский

Citations

0