The association between neighborhood-level social fragmentation and distressing psychotic-like experiences in early adolescence: the moderating role of close friends

Psychological Medicine, Journal Year: 2024, Volume and Issue: 54(9), P. 2172 - 2180

Published: Feb. 16, 2024

Early exposure to neighborhood social fragmentation has been shown be associated with schizophrenia. The impact of and friendships on distressing psychotic-like experiences (PLE) remains unknown. We investigate the relationships between fragmentation, number friends, PLE among early adolescents.

Language: Английский

---

A meta-analysis of loneliness and risk of dementia using longitudinal data from >600,000 individuals

Nature Mental Health, Journal Year: 2024, Volume and Issue: 2(11), P. 1350 - 1361

Published: Oct. 9, 2024

Language: Английский

---

The Impact of Socioeconomic Factors on Cognitive Ability in Community-Dwelling Older Adults: Mediating Effect of Social Participation and Social Support

Healthcare, Journal Year: 2025, Volume and Issue: 13(5), P. 551 - 551

Published: March 4, 2025

Previous studies have shown that socioeconomic status influences cognitive health in adults. Therefore, it is important for the development of healthy aging policies to further investigate effect specific factors on function older people and possible mechanism. In this study, three (i.e., income, occupation, education) were used as independent variables, social support participation parallel or serial mediating variables community-dwelling adults pathway influence. A cross-sectional study was conducted Pudong New District Shanghai, China. total 970 aged over 60 years old who had lived their current location more than 5 enrolled. Socioeconomic adults, including education level, occupation before retirement, investigated, levels measured using MoCA, MSPSS, quantity activities, respectively. Covariates, lifestyle, status, sleep quality, nutritional assessed a self-designed questionnaire, PSQI, MNA-SF scale. Omnibus mediation analysis adopted examine effect, performed SPSS PROCESS program. Community-dwelling with higher complex level better function, βmedium income = 1.949 βhigh 3.799 compared low-income (all p < 0.001), occupational complexity 1.262 1.574 low 0.01), 1.814 1.511 0.001). Social significantly mediated above relationship 0.001); relative indirect medium high through respectively 0.356 0.777 accounting 18.36% 20.45% effect; (β) 0.358 0.561, 28.36% 35.64% while 0.311 0.562, 17.14% 39.19% effect. being 0.132 0.160, 0.096 0.156, respectively, 4.21% 6.77%, 5.29% 10.32%, effects. Serial showed affected subsequently effects 0.065 0.078, 0.043 0.070, 3.3% 2.0%, 2.4-4.6% This demonstrates independently cumulatively mediate between conditions improving systems encouraging actively participate activities may be beneficial preventing decline The findings also provide new insights future improvement future.

Language: Английский

---

Rural Roads to cognitive Resilience (RRR): A prospective cohort study protocol

PLoS ONE, Journal Year: 2025, Volume and Issue: 20(1), P. e0312660 - e0312660

Published: Jan. 13, 2025

Ambient air pollution, detrimental built and social environments, isolation (SI), low socioeconomic status (SES), rural (versus urban) residence have been associated with cognitive decline risk of Alzheimer's disease related dementias (ADRD). Research is needed to investigate the influence ambient pollution environments on SI among rural, disadvantaged, ethnic minority communities. To address this gap, cohort study will recruit an ethnoracially diverse, Florida sample in geographic proximity seasonal agricultural burning. We (1) examine contributions smoke-related fine particulate matter (PM2.5) exposures function; (2) determine effects (3) contextualize function residents from different ethnoracial groups during burn non-burn seasons. 1,087 community-dwelling, dementia-free, ≥45-year-olds five communities Florida's Lake Okeechobee region. Over 36 months, participants complete baseline visits collect demographics, health history, measurements (e.g., blood pressure, body mass index) 6-month follow-ups assessing at each visit. A subsample 120 representative community wear smartwatches sensor data heart rate) daily routine predefined activities GPS-captured travel, frequent destinations) over two months. Ecological momentary assessments (EMA) whether smoke has bothered participant last 30 minutes) occur months burning non-burning PurpleAir monitors (36 total) be installed continuously monitor outdoor PM2.5 levels. expect identify individual- community-level factors that increase for a vulnerable population.

Language: Английский

---

Loneliness and cognition in older adults: A meta-analysis of harmonized studies from the United States, England, India, China, South Africa, Mexico, and Chile

Psychological Medicine, Journal Year: 2025, Volume and Issue: 55

Published: Jan. 1, 2025

Abstract Background Loneliness is a risk factor for late-life dementia. There less consistent evidence of its association with cognitive performance. This study examined the replicability between loneliness and overall domain-specific function informant-rated decline in cohorts from seven countries: United States, England, India, China, South Africa, Mexico, Chile. Methods Data were Harmonized Cognitive Assessment Protocol administered population-based studies (total N > 20,000). Participants reported their loneliness, completed battery tests, nominated knowledgeable informant to rate decline. Random-effect meta-analyses used summarize associations each cohort. Results was associated poor performance controlling sociodemographic factors (meta-analytic correlation cognition = −.10 [95% CI −.13, −.06] .16 .14, .17]). Despite some heterogeneity, significant across samples Asia, Europe, North, Central, America. The meta-analysis also indicated an specific domains: episodic memory, speed-attention, visuospatial abilities, numeric reasoning, verbal fluency. attenuated but persisted when depressive symptoms added as covariate. Depression, impairment, did not consistently moderate samples. Conclusions multiple domains observer-rated decline, that replicated diverse world regions cultures.

Language: Английский

---

Social health and prevention of dementia: Integration of human and mice studies

International Psychogeriatrics, Journal Year: 2025, Volume and Issue: unknown, P. 100054 - 100054

Published: March 1, 2025

Prevention of dementia is considered a healthcare priority. We aimed to identify potentially modifiable risk factors and mechanisms within the social health domain find novel avenues prevent cognitive decline dementia. integrated results eight sub-studies Social Health in Mice Men (SHiMMy) project that were separately published specialized journals, but not yet jointly considered. followed integrative methodology Whittemore Knafl, using conceptual framework for structure integrate human epidemiological qualitative studies experimental mice studies. This multi-method approach. Participants population-based longitudinal cohort Rotterdam study included epidemiolocal (ranging from N = 1259 3.720) (n 17). intervention performed transgenic mouse model Alzheimer's pathology matched controls, under group single housed conditions. Epidemiological include markers (loneliness, perceived support, marital status) magnetic resonance imaging brain. The semi-structured used an interview guide. assessed behavioral histological markers. In studies, we identified several similar (e.g. status, size) protective responses) factors. alignment findings showing may impact brain lend further support our hypothesis. These allow us propose evidence-based targets preventive interventions.

Language: Английский

---

Positive global mental health: an overview

Published: March 6, 2025

At present, most healthcare systems are reactive, focusing on symptom control. They over-emphasize impairments, disorders, disabilities, and risk factors, without sufficient attention to individuals’ communities’ strengths, positive psychosocial characteristics, protective preventive the promotion of well-being. This disorder-oriented approach may contribute a broadening gap between service needs rapidly increasing urbanized world population supply adequately qualified providers. It is critical assess enhance personal such as resilience, wisdom, optimism, compassion, spirituality, purpose in life, along with social connections support. Strong evidence supports value determinants health, which reduce mental illnesses, improve long-term course, promote recovery persons serious illnesses physical maladies. The primary prevention can be operationalized. Appropriate strategies should culturally sensitive, applying interventions that appropriate local community. Interventions informed by biological similarities etiopathology across globe, but also diverse expressions varied people from communities. Recent reports global behavioral pandemic loneliness, isolation, suicides, drug abuse point an urgent need for developing therapeutic at both individual societal levels well-being general population, including illnesses. There potentially exciting examples age-friendly communities, intergenerational activities, digital support well health. important medicine psychiatry their focus diseases factors health factors.

Language: Английский

---

Cognitive Health Behaviours and Their Association with Neuroanatomical Changes in the Progression of Alzheimer's Disease and Cognitive Impairment

American Journal of Health Behavior, Journal Year: 2025, Volume and Issue: 49(1), P. 14 - 22

Published: Jan. 31, 2025

Background: Patients suffering from Alzheimer's disease usually experience different neuroanatomical changes such as depression, apathy and irritability. Other cognitive behaviours found are linked with impairment well disease. Cardiovascular issues also to be common among the patients, Aim of Study: This study aims assess health behavior their association within progression impairment. For this purpose, hyperintensities in white matter (WHM) were observed. Methodology: In current longitudinal study, grey atrophy WMH changes, is observed cohort. regard, 120 participants included while 310 220 control groups incorporated. Neuroanatomical determined by using Neuropsychiatric Inventory, which classified into apathy, affective hyperactivity subsyndromes. Automatic technique was used for measuring WMH. Results: The results obtained linear mixed-effects models show that has a significant other subsyndromes groups. Significant context vascular risks. Conclusion: identified major contributor NPS moderate

Language: Английский

---

Addressing social determinants of health in individuals with mental disorders in clinical practice: review and recommendations

Translational Psychiatry, Journal Year: 2025, Volume and Issue: 15(1)

Published: April 3, 2025

Language: Английский

---

Evidence‐based facilitator strategies for enhancing social engagement in groups of older adults with ADRD

Alzheimer s & Dementia, Journal Year: 2025, Volume and Issue: 21(4)

Published: April 1, 2025

Abstract INTRODUCTION Alzheimer's disease and related dementias (ADRD) is exacerbated by social isolation. One potential intervention for improving the health outcomes of individuals with ADRD providing opportunities socialization that are highly engaging. METHODS To identify strategies enhancing engagement, we studied recorded virtual group sessions older adults aged ≥ 65, mild to moderate who interacted younger adult facilitators. We developed multivariate regression models use data describing behavior, activity, composition predict enhanced engagement. RESULTS identified predictors engagement composition, structure, leadership, mode delivery. These results inform designing settings which maximize using synergistic influence whole groups on individuals. DISCUSSION make evidence‐based treatment recommendations facilitators seeking future research investigating preservation or loss Highlights Social isolation a major contributing factor development dementias. Virtual can help mitigate lack opportunity contact. Audio–video activity were used Group size, time spoken contributed Experienced maximized supporting conversation.

Language: Английский

---