Circularly polarized luminescence in chiral materials

Matter, Journal Year: 2022, Volume and Issue: 5(3), P. 837 - 875

Published: Feb. 3, 2022

Language: Английский

---

Metal-organic materials with circularly polarized luminescence

Coordination Chemistry Reviews, Journal Year: 2022, Volume and Issue: 468, P. 214640 - 214640

Published: June 2, 2022

Language: Английский

---

Engineering Au₄₄ Nanoclusters for NIR-II Luminescence Imaging-Guided Photoactivatable Cancer Immunotherapy

ACS Nano, Journal Year: 2023, Volume and Issue: 17(16), P. 15605 - 15614

Published: July 28, 2023

Immunotherapy is an advanced therapeutic strategy of cancer treatment but suffers from the issues off-target adverse effects, lack real-time monitoring techniques, and unsustainable response. Herein, ultrasmall Au nanocluster (NC)-based theranostic probe designed for second near-infrared window (NIR-II) photoluminescence (PL) imaging-guided phototherapies photoactivatable immunotherapy. The (Au44MBA26-NLG short) composed atomically precise NIR-II emitting Au44MBA26 NCs (here MBA denotes water-soluble 4-mercaptobenzoic acid) conjugated with immune checkpoint inhibitor 1-cyclohexyl-2-(5H-imidazo[5,1-a]isoindol-5-yl)ethanol (NLG919) via a singlet oxygen (1O2)-cleavable linker. Upon NIR photoirradiation, Au44MBA26-NLG not only enables PL imaging tumors in deep tissues guiding tumor therapy also allows leverage photothermal property (PTT) photogenerated 1O2 photodynamic (PDT) releasing NLG919 Such multiple effect modulated by prompts proliferation activation effector T cells, upshifts systemic antitumor T-lymphocyte (T cell) immunity, finally suppresses growth both primary distant living mice. Overall, this study may provide promising nanoplatform toward

Language: Английский

---

Chemical Flexibility of Atomically Precise Metal Clusters

Chemical Reviews, Journal Year: 2024, Volume and Issue: 124(11), P. 7262 - 7378

Published: May 2, 2024

Ligand-protected metal clusters possess hybrid properties that seamlessly combine an inorganic core with organic ligand shell, imparting them exceptional chemical flexibility and unlocking remarkable application potential in diverse fields. Leveraging to expand the library of available materials stimulate development new functionalities is becoming increasingly pressing requirement. This Review focuses on origin from structural analysis, including intra-cluster bonding, inter-cluster interactions, cluster-environments metal-to-ligand ratios, thermodynamic effects. In introduction, we briefly outline explain differences commonalities M(I)/M(I/0) coinage clusters. Additionally, distinguish bonding characteristics atoms core, which give rise their distinct flexibility. Section 2 delves into categories, theories related following sections 3 7, primarily elucidate mechanisms trigger flexibility, dynamic processes transformation, resultant alterations structure, ensuing modifications physical–chemical properties. 8 presents notable applications have emerged utilizing assemblies. Finally, section 9, discuss future challenges opportunities within this area.

Language: Английский

---

Molecularly Engineered Room-Temperature Phosphorescence for Biomedical Application: From the Visible toward Second Near-Infrared Window

Chemical Reviews, Journal Year: 2023, Volume and Issue: 123(24), P. 13966 - 14037

Published: Nov. 22, 2023

Phosphorescence, characterized by luminescent lifetimes significantly longer than that of biological autofluorescence under ambient environment, is great value for biomedical applications. Academic evidence fluorescence imaging indicates virtually all metrics (sensitivity, resolution, and penetration depths) are improved when progressing into wavelength regions, especially the recently reported second near-infrared (NIR-II, 1000–1700 nm) window. Although emission probes does matter, it not clear whether guideline "the wavelength, better effect" still suitable developing phosphorescent probes. For tissue-specific bioimaging, long-lived probes, even if they emit visible phosphorescence, enable accurate visualization large deep tissues. studies dealing with bioimaging tiny architectures or dynamic physiopathological activities, prerequisite rigorous planning long-wavelength being aware cooperative contribution long wavelengths improving spatiotemporal depth, sensitivity bioimaging. In this Review, emerging molecular engineering methods room-temperature phosphorescence discussed through lens photophysical mechanisms. We highlight roles from to NIR-II windows toward bioapplications. To appreciate such advances, challenges prospects in rapidly growing described.

Language: Английский

---

Molecule-like synthesis of ligand-protected metal nanoclusters

Nature Reviews Materials, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 5, 2024

Language: Английский

---

Interactions of Metal Nanoclusters with Light: Fundamentals and Applications

Advanced Materials, Journal Year: 2021, Volume and Issue: 34(25)

Published: Oct. 7, 2021

The interactions of materials with light determine their applications in various fields. In the past decade, ultrasmall metal nanoclusters (NCs) have emerged as a promising class optical due to unique molecular-like properties. Herein, basic principles absorption and photoluminescence NCs, polarized light, light-induced chemical reactions, are discussed, highlighting roles core protecting ligands/motifs NCs light. electronic structures which closely related addition, contribute chiral origin, further promoting through pathways. fundamentals light-NC provide guidance for design applications, discussed second part. last section, some strategies proposed understand interactions, challenges opportunities. It is hoped that this work will stimulate more research on properties

Language: Английский

---

Chiral Superatomic Nanoclusters Ag₄₇ Induced by the Ligation of Amino Acids

Angewandte Chemie International Edition, Journal Year: 2021, Volume and Issue: 60(20), P. 11430 - 11435

Published: Feb. 25, 2021

Abstract Silver nanoclusters containing Ag 0 atoms protected by amino acids were synthesized and characterized. Chiral superatomic silver [Ag 47 L 12 (C≡C t Bu) 16 ]BF 4 (L= l‐/d ‐valine or ‐isoleucine) have been prepared reducing AgC≡C Bu (AAs) with NaBH . Single crystal X‐ray diffraction revealed that these clusters T symmetry, the metal kernel can be viewed as a tetracapped truncated tetrahedron (Ag 17 ) surrounded six W‐shaped 5 units. The are homochiral evidenced CD measurements. As for strong signals, large contributions found from occupied s,p states (superatomic D states) near Fermi level. Electron counting 18‐electron systems, suggesting they clusters. nature 1S 2 1P 6 1D 10 configuration was supported DFT calculations. This work paves way of taking AAs facile chiral induction agents synthesis nanoclusters.

Language: Английский

---

Synthesis and enantioseparation of chiral Au₁₃ nanoclusters protected by bis-N-heterocyclic carbene ligands

Chemical Science, Journal Year: 2021, Volume and Issue: 12(31), P. 10436 - 10440

Published: Jan. 1, 2021

A series of chiral Au 13 nanoclusters were synthesized via the direct reduction achiral dinuclear Au( i ) halide complexes ligated by ortho -xylyl-linked bis- N -heterocyclic carbene (NHC) ligands.

Language: Английский

---

Symmetry Breaking of Atomically Precise Fullerene-like Metal Nanoclusters

Journal of the American Chemical Society, Journal Year: 2021, Volume and Issue: 143(32), P. 12439 - 12444

Published: Aug. 6, 2021

Here we report a neutral fullerene-like core–shell homosilver Ag13@Ag20 nanocluster that is fully protected by an achiral bidentate thiolate ligand (9,12-dimercapto-1,2-closo-carborane, C2B10H10S2H2), which crystallizes in centrosymmetric space group R3̅. Continuous Cu doping the dodecahedral shell first induced symmetry breaking to generate chiral Ag13@Ag20-nCun (6 ≥ n 2) containing two acetonitrile ligands P212121, and then produced symmetric all-thiolated (20 13) higher Im3̅. The selectively copper-doped cluster has its structure reorganized lower shows chiroptical activity. Moreover, structural distortion of further expanded R-/S-propylene oxide, more prominent core-based CD response. This work revealed novel mechanism chirality generation at atomic level through asymmetric shell-doping metal nanoclusters, provides new insight into origin inorganic nanostructures.

Language: Английский

---