Chemical Engineering Journal, Journal Year: 2025, Volume and Issue: unknown, P. 160763 - 160763
Published: Feb. 1, 2025
Language: Английский
Analytical Chemistry, Journal Year: 2023, Volume and Issue: 95(23), P. 8906 - 8913
Published: June 2, 2023
Developing highly active and sensitive nanozymes for biothiol analysis is of vital significance due to their essential roles in disease diagnosis. Herein, two metal ion-doped carbon dots (M-CDs) with high peroxidase-like activity were designed prepared detection identification through the colorimetric sensor array technique. The M-CDs can strongly catalyze decomposition H2O2, accompanied by color changes 3,3′,5,5′-tetramethylbenzidine (TMB) from colorless blue, indicating peroxidase-mimicking activities M-CDs. Compared pure (CDs), exhibited enhanced owing synergistic effect between ions CDs. However, strong binding affinity biothiols ions, catalytic could be inhibited different diverse degrees. Therefore, using TMB as a chromogenic substrate presence developed form differential fingerprints three most important (i.e., cysteine (Cys), homocysteine (Hcy), glutathione (GSH)), which accurately discriminated pattern recognition methods hierarchical clustering (HCA) principal component (PCA)) limit 5 nM. Moreover, single various concentrations mixtures was also realized. Furthermore, actual samples such cells sera well distinguished as-fabricated array, demonstrating its potential
Language: Английский
Citations
62
Chemical Communications, Journal Year: 2023, Volume and Issue: 59(24), P. 3507 - 3522
Published: Jan. 1, 2023
Recent advances and challenges in developing electrochemiluminescence biosensors for health analysis are reviewed.
Language: Английский
Citations
49
Angewandte Chemie International Edition, Journal Year: 2023, Volume and Issue: 62(44)
Published: Sept. 12, 2023
Copper nanoclusters (CuNCs) are emerging electrochemiluminescence (ECL) emitters with unique molecule-like electronic structures, high abundance, and low cost. However, the synthesis of CuNCs ECL efficiency stability in a scalable manner remains challenging. Here, we report facile gram-scale approach for preparing self-assembled (CuNCsAssy ) induced by ligands exceptionally boosted anodic stability. Compared to disordered aggregates that inactive ECL, CuNCsAssy shows record (10 %, wavelength-corrected, relative Ru(bpy)3 Cl2 /tripropylamine). Mechanism studies revealed unusual dual functions simultaneously facilitating electrochemical excitation radiative transition. Moreover, assembly addressed limitation poor conventional CuNCs. As proof concept, an biosensor alkaline phosphatase detection was successfully constructed ultralow limit 8.1×10-6 U/L.
Language: Английский
Citations
46
Coordination Chemistry Reviews, Journal Year: 2025, Volume and Issue: 531, P. 216520 - 216520
Published: Feb. 12, 2025
Language: Английский
Citations
3
Science China Chemistry, Journal Year: 2022, Volume and Issue: 65(12), P. 2417 - 2436
Published: Oct. 8, 2022
Language: Английский
Citations
48
Materials Chemistry Frontiers, Journal Year: 2023, Volume and Issue: 7(22), P. 5561 - 5660
Published: Jan. 1, 2023
This review provides an overview of the progress in development AIE-based organic small molecule probes for detecting biologically important molecules, drug volatile compounds, and explosives over past five years.
Language: Английский
Citations
40
TrAC Trends in Analytical Chemistry, Journal Year: 2023, Volume and Issue: 169, P. 117376 - 117376
Published: Oct. 18, 2023
Language: Английский
Citations
34
Analytical Chemistry, Journal Year: 2023, Volume and Issue: 95(17), P. 7045 - 7052
Published: April 20, 2023
A novel sandwich electrochemiluminescence (ECL) biosensor based on aggregation-induced resonance energy transfer (AIECL-RET) was designed for the sensitive detection of amyloid β42 (Aβ42). The synthesized silver nanoparticle-functionalized zinc metal–organic framework (Ag@ZnPTC) and gold zirconium organic (Au@UiO-66-NH2) were used as ECL donor acceptor, respectively. AgNPs generated in situ surface ZnPTC, which further improved intensity loading antibody 1 (Ab1). Under optimized experimental conditions, linear range Aβ42 concentration 10 fg/mL to 100 ng/mL, limit 2.4 (S/N = 3). recoveries 99.5–104%. method has good stability, repeatability, specificity. Ag@ZnPTC/Au@UiO-66-NH2 provides an assay disease biomarkers.
Language: Английский
Citations
31
Angewandte Chemie International Edition, Journal Year: 2023, Volume and Issue: 62(46)
Published: Sept. 25, 2023
Abstract The precisely modulated synthesis of programmable light‐emitting materials remains a challenge. To address this challenge, we construct four tetraphenylethylene‐based supramolecular architectures (SA, SB, SC, and SD), revealing that they exhibit higher electrochemiluminescence (ECL) intensities efficiencies than the tetraphenylethylene monomer can be classified as highly efficient intramolecular aggregation–induced (PI‐AIECL) systems. best‐performing system (SD) shows high ECL cathodic efficiency exceeding benchmark tris(2,2′‐bipyridyl)ruthenium(II) chloride in aqueous solution by nearly six‐fold. electrochemical characterization these an organic solvent provides deeper mechanistic insights, SD features lowest band gap. Density functional theory calculations indicate gap guest ligand structure is smallest most closely matched to host scaffold. Finally, used realize ECL‐based cysteine detection (detection limit=14.4 nM) real samples. Thus, study not only strategy allowing chromophores controllably regulated on molecular scale, but also inspires high‐performance aggregation‐induced emitters.
Language: Английский
Citations
27
Sensors and Actuators B Chemical, Journal Year: 2024, Volume and Issue: 405, P. 135383 - 135383
Published: Jan. 25, 2024
Language: Английский
Citations
17