Biosensors,
Journal Year:
2025,
Volume and Issue:
15(3), P. 155 - 155
Published: March 2, 2025
High-sensitivity
and
high-specificity
biodetection
is
critical
for
advancing
applications
in
life
sciences,
biosafety,
food
safety,
environmental
monitoring.
CRISPR/Cas
systems
have
emerged
as
transformative
tools
biosensing
due
to
their
unparalleled
specificity,
programmability,
unique
enzymatic
activities.
They
exhibit
two
key
cleavage
behaviors:
precise
ON-target
guided
by
specific
protospacers,
which
ensures
accurate
target
recognition,
bystander
activity
triggered
upon
binding,
enables
robust
signal
amplification.
These
properties
make
highly
versatile
designing
biosensors
ultra-sensitive
detection.
This
review
comprehensively
explores
recent
advancements
system-based
biosensors,
highlighting
impact
on
improving
performance.
We
discuss
the
integration
of
with
diverse
readout
mechanisms,
including
electrochemical,
fluorescent,
colorimetric,
surface-enhanced
Raman
scattering
(SERS),
so
on.
Additionally,
we
examine
development
integrated
systems,
such
microfluidic
devices
portable
leverage
technology
point-of-care
testing
(POCT)
high-throughput
analysis.
Furthermore,
identify
unresolved
challenges,
aiming
inspire
innovative
solutions
accelerate
translation
these
technologies
into
practical
diagnostics,
food,
environment
safety.
Analytical Chemistry,
Journal Year:
2024,
Volume and Issue:
96(18), P. 7073 - 7081
Published: April 25, 2024
A
spatial-potential-color-resolved
bipolar
electrode
electrochemiluminescence
biosensor
(BPE-ECL)
using
a
CuMoOx
electrocatalyst
was
constructed
for
the
simultaneous
detection
and
imaging
of
tetracycline
(TET)
lincomycin
(LIN).
HOF-101
emitted
peacock
blue
light
under
positive
potential
scanning,
CdSe
quantum
dots
(QDs)
green
negative
scanning.
could
catalyze
electrochemical
reduction
H2O2
to
greatly
increase
Faradic
current
BPE
realize
ECL
signal
amplification.
In
channel
1,
CuMoOx-Aptamer
II
probes
were
introduced
into
hole
(left
groove
A)
by
dual
aptamer
sandwich
method
TET.
During
polarity
negative,
resulting
in
catalyzed
CuMoOx,
enhanced
detecting
2,
(LIN)
adsorbed
on
MXene
driving
(DVE)
B)
hydrogen-bonding
metal-chelating
interactions.
LIN
bound
with
its
aptamers,
causing
fall
off.
DVE
decreased.
The
QDs
reduced
LIN.
Furthermore,
portable
mobile
phone
platform
built
colorimetric
(CL)
TET
Thus,
multiple
mode-resolved
be
realized
simultaneously
only
one
scan,
which
improved
accuracy
efficiency.
This
study
opened
new
technology
BPE-ECL
sensor
application
is
expected
shine
microchips
point-of-care
testing
(POCT).
Comprehensive Reviews in Food Science and Food Safety,
Journal Year:
2024,
Volume and Issue:
23(3)
Published: April 5, 2024
Abstract
The
importance
of
food
quality
and
safety
lies
in
ensuring
the
best
product
to
meet
consumer
demands
public
health.
Advanced
technologies
play
a
crucial
role
minimizing
risk
foodborne
illnesses,
contamination,
drug
residue,
other
potential
hazards
food.
Significant
materials
technological
advancements
have
been
made
throughout
supply
chain.
Among
them,
quantum
dots
(QDs),
as
class
advanced
nanomaterials
with
unique
physicochemical
properties,
are
progressively
demonstrating
their
value
field
safety.
This
review
aims
explore
cutting‐edge
research
on
different
applications
QDs
safety,
including
encapsulation
bioactive
compounds,
detection
analytes,
preservation
packaging,
intelligent
freshness
indicators.
Moreover,
modification
strategies
toxicities
diverse
outlined,
which
can
affect
performance
hinder
industry.
findings
suggested
that
mainly
used
analyte
active/intelligent
packaging.
Various
analytes
be
detected
using
QD‐based
sensors,
heavy
metal
ions,
pesticides,
antibiotics,
microorganisms,
additives,
functional
components.
QD
incorporation
aided
improving
antibacterial
antioxidant
activities
film/coatings,
resulting
extended
shelf
life
for
packaged
Finally,
perspectives
critical
challenges
productivity,
toxicity,
practical
application
also
summarized.
By
consolidating
these
essential
aspects
into
this
review,
way
developing
high‐performance
is
presented
researchers
technologists
better
capitalize
upon
technology
applications.
